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Recent research has shown the potential for neural networks to improve upon classical survival models such as the Cox model, which is widely used in clinical practice. Neural networks, however, typically rely on data that are centrally…

Machine Learning · Computer Science 2022-07-12 Dekai Zhang , Francesca Toni , Matthew Williams

Variable selection in high dimensional space has challenged many contemporary statistical problems from many frontiers of scientific disciplines. Recent technology advance has made it possible to collect a huge amount of covariate…

Machine Learning · Statistics 2010-05-20 Jianqing Fan , Yang Feng , Yichao Wu

Many existing approaches for generating predictions in settings with distribution shift model distribution shifts as adversarial or low-rank in suitable representations. In various real-world settings, however, we might expect shifts to…

Machine Learning · Statistics 2023-10-31 Kirk Bansak , Elisabeth Paulson , Dominik Rothenhäusler

Survival data with time-varying covariates are common in practice. If relevant, they can improve on the estimation of survival function. However, the traditional survival forests - conditional inference forest, relative risk forest and…

Applications · Statistics 2022-06-06 Weichi Yao , Halina Frydman , Denis Larocque , Jeffrey S. Simonoff

Although the Cox proportional hazards model is well established and extensively used in the analysis of survival data, the proportional hazards (PH) assumption may not always hold in practical scenarios. The class of semiparametric…

Methodology · Statistics 2025-10-21 Junkai Yin , Yue Zhang , Zhangsheng Yu

Ten years ago, CUPED (Controlled Experiments Utilizing Pre-Experiment Data) mainstreamed the idea of variance reduction leveraging pre-experiment covariates. Since its introduction, it has been implemented, extended, and modernized by major…

Applications · Statistics 2023-12-06 Alex Deng , Luke Hagar , Nathaniel Stevens , Tatiana Xifara , Lo-Hua Yuan , Amit Gandhi

The most popular approach for analyzing survival data is the Cox regression model. The Cox model may, however, be misspecified, and its proportionality assumption may not always be fulfilled. An alternative approach for survival prediction…

Machine Learning · Statistics 2018-05-17 Marvin N. Wright , Theresa Dankowski , Andreas Ziegler

Cox proportional hazard regression model is a popular tool to analyze the relationship between a censored lifetime variable with other relevant factors. The semi-parametric Cox model is widely used to study different types of data arising…

Methodology · Statistics 2018-10-09 Abhik Ghosh , Ayanendranath Basu

Artificial Intelligence (AI) is often an integral part of modern decision support systems. The best-performing predictive models used in AI-based decision support systems lack transparency. Explainable Artificial Intelligence (XAI) aims to…

Machine Learning · Computer Science 2025-02-25 Tuwe Löfström , Helena Löfström , Ulf Johansson , Cecilia Sönströd , Rudy Matela

Survival regression aims to predict the time when an event of interest will take place, typically a death or a failure. A fully parametric method [18] is proposed to estimate the survival function as a mixture of individual parametric…

Machine Learning · Computer Science 2024-04-25 Qinxin Wang , Jiayuan Huang , Junhui Li , Jiaming Liu

Recommendation systems (RS) aim to provide personalized content, but they face a challenge in unbiased learning due to selection bias, where users only interact with items they prefer. This bias leads to a distorted representation of user…

Machine Learning · Computer Science 2025-06-10 Shuqiang Zhang , Yuchao Zhang , Jinkun Chen , Haochen Sui

With the current ongoing debate about fairness, explainability and transparency of machine learning models, their application in high-impact clinical decision-making systems must be scrutinized. We consider a real-life example of risk…

Machine Learning · Computer Science 2020-11-13 Sandhya Tripathi , Bradley A. Fritz , Mohamed Abdelhack , Michael S. Avidan , Yixin Chen , Christopher R. King

This paper introduces a new approach to address the issue of class imbalance in graph neural networks (GNNs) for learning on graph-structured data. Our approach integrates imbalanced node classification and Bias-Variance Decomposition,…

Machine Learning · Computer Science 2025-02-26 Liang Yan , Gengchen Wei , Chen Yang , Shengzhong Zhang , Zengfeng Huang

In high-dimensional survival analysis, effective variable selection is crucial for both model interpretation and predictive performance. This paper investigates Cox regression with lasso and adaptive lasso penalties in genomic datasets…

Methodology · Statistics 2025-07-02 Pilar González-Barquero , Rosa E. Lillo , Álvaro Méndez-Civieta

Choosing relevant predictors is central to the analysis of biomedical time-to-event data. Classical frequentist inference, however, presumes that the set of covariates is fixed in advance and does not account for data-driven variable…

Methodology · Statistics 2026-02-10 Lena Schemet , Sarah Friedrich-Welz

We apply Gaussian process (GP) regression, which provides a powerful non-parametric probabilistic method of relating inputs to outputs, to survival data consisting of time-to-event and covariate measurements. In this context, the covariates…

Statistics Theory · Mathematics 2014-09-08 James E. Barrett , Anthony C. C. Coolen

A new modification of the Neural Additive Model (NAM) called SurvNAM and its modifications are proposed to explain predictions of the black-box machine learning survival model. The method is based on applying the original NAM to solving the…

Machine Learning · Computer Science 2021-04-20 Lev V. Utkin , Egor D. Satyukov , Andrei V. Konstantinov

Regression analysis with missing data is a long-standing and challenging problem, particularly when there are many missing variables with arbitrary missing patterns. Likelihood-based methods, although theoretically appealing, are often…

Methodology · Statistics 2024-10-16 Ngok Sang Kwok , Kin Yau Wong

This work addresses inverse linear optimization where the goal is to infer the unknown cost vector of a linear program. Specifically, we consider the data-driven setting in which the available data are noisy observations of optimal…

Optimization and Control · Mathematics 2021-12-07 Rishabh Gupta , Qi Zhang

The difference in restricted mean survival times between two groups is a clinically relevant summary measure. With observational data, there may be imbalances in confounding variables between the two groups. One approach to account for such…

Applications · Statistics 2014-10-17 Andrew Wey , David Vock , John Connett , Kyle Rudser