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Many biological systems dynamically rearrange their components through a sequence of configurations in order to perform their functions. Such dynamic processes have been studied using network models that sequentially retrieve a set of…

Statistical Mechanics · Physics 2022-12-01 Lukas Herron , Pablo Sartori , BingKan Xue

Negative feedback is a powerful approach capable of improving several aspects of a system. In linear electronics, it has been critical for allowing invariance to device properties. Negative feedback is also known to enhance linearity in…

Instrumentation and Detectors · Physics 2016-11-22 Luciano da F. Costa , Filipi N. Silva , Cesar H. Comin

Non-stationary online learning has drawn much attention in recent years. Despite considerable progress, dynamic regret minimization has primarily focused on convex functions, leaving the functions with stronger curvature (e.g., squared or…

Machine Learning · Computer Science 2025-06-13 Yu-Jie Zhang , Peng Zhao , Masashi Sugiyama

In addition to high accuracy, robustness is becoming increasingly important for machine learning models in various applications. Recently, much research has been devoted to improving the model robustness by training with noise…

Machine Learning · Computer Science 2021-03-30 Kun-Peng Ning , Lue Tao , Songcan Chen , Sheng-Jun Huang

Refinement is a powerful mechanism for mastering the complexities that arise when formally modelling systems. Refinement also brings with it additional proof obligations -- requiring a developer to discover properties relating to their…

Logic in Computer Science · Computer Science 2011-06-22 Maria Teresa Llano , Andrew Ireland , Alison Pease

I assess various proposals for the source of the intuition that there is something problematic about contextuality, ultimately concluding that contextuality is best thought of in terms of fine-tuning. I then argue that as with other…

Quantum Physics · Physics 2021-11-24 Emily Adlam

Continual learning can enable neural networks to evolve by learning new tasks sequentially in task-changing scenarios. However, two general and related challenges should be overcome in further research before we apply this technique to…

Machine Learning · Computer Science 2022-02-15 Yujiang He , Zhixin Huang , Bernhard Sick

While Large Language Models (LLMs) have demonstrated exceptional multitasking abilities, fine-tuning these models on downstream, domain-specific datasets is often necessary to yield superior performance on test sets compared to their…

Computation and Language · Computer Science 2024-03-15 Haoran Yang , Yumeng Zhang , Jiaqi Xu , Hongyuan Lu , Pheng Ann Heng , Wai Lam

Context-based fine-tuning methods, including prompting, in-context learning, soft prompting (also known as prompt tuning), and prefix-tuning, have gained popularity due to their ability to often match the performance of full fine-tuning…

Machine Learning · Computer Science 2024-04-10 Aleksandar Petrov , Philip H. S. Torr , Adel Bibi

Reinforcement learning has been successfully applied to the problem of tuning PID controllers in several applications. The existing methods often utilize function approximation, such as neural networks, to update the controller parameters…

Feedback is a most important concept in control systems, its main purpose is to deal with internal and/or external uncertainties in dynamical systems, by using the on-line observed information. Thus, a fundamental problem in control theory…

Optimization and Control · Mathematics 2007-05-23 Lei Guo

Mixed positive and negative feedback loops are often found in biological systems which support oscillations. In this work we consider a prototype of such systems, which has been recently found at the core of many genetic circuits showing…

Statistical Mechanics · Physics 2015-06-03 Ashok Garai , Bartlomiej Waclaw , Hannes Nagel , Hildegard Meyer-Ortmanns

A monotonic, non-kernel density variant of the density-matching technique for optimization under uncertainty is developed. The approach is suited for turbomachinery problems which, by and large, tend to exhibit monotonic variations in the…

Applications · Statistics 2016-05-25 Pranay Seshadri , Geoffrey Parks , Shahrokh Shahpar

Transformers have demonstrated exceptional performance across a wide range of domains. While their ability to perform reinforcement learning in-context has been established both theoretically and empirically, their behavior in…

Machine Learning · Statistics 2025-10-24 Baiyuan Chen , Shinji Ito , Masaaki Imaizumi

Turing patterns play a fundamental role in morphogenesis and population dynamics, encoding key information about the underlying biological mechanisms. Yet, traditional inverse problems have largely relied on non-biological data such as…

Analysis of PDEs · Mathematics 2025-09-10 Yuhan Li , Hongyu Liu , Catharine W. K. Lo

Can transformers generalize efficiently on problems that require dealing with examples with different levels of difficulty? We introduce a new task tailored to assess generalization over different complexities and present results that…

Molecular simulations and biophysical experiments can be used to provide independent and complementary insights into the molecular origin of biological processes. A particularly useful strategy is to use molecular simulations as a modelling…

Chemical Physics · Physics 2019-12-10 Simone Orioli , Andreas Haahr Larsen , Sandro Bottaro , Kresten Lindorff-Larsen

Statistical properties of environments experienced by biological signaling systems in the real world change, which necessitate adaptive responses to achieve high fidelity information transmission. One form of such adaptive response is gain…

Molecular Networks · Quantitative Biology 2012-05-01 Ilya Nemenman

Molecular biology features numerous complexes of proteins that coordinate in an interlocking fashion to fulfill different functions. Adaptive evolution explains some of this complexity, but needn't be the default when neutral explanations…

Neural and Evolutionary Computing · Computer Science 2026-04-21 Andrew Walsh

Traditional methods in educational research often fail to capture the complex and evolving nature of learning processes. This chapter examines the use of complex systems theory in education to address these limitations. The chapter covers…

Computers and Society · Computer Science 2025-02-03 Mohammed Saqr , Daryn Dever , Sonsoles López-Pernas , Christophe Gernigon , Gwen Marchand , Avi Kaplan