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Related papers: Clustering of time-course gene expression profiles…

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In this paper, we present a new approach for analyzing gene expression data that builds on topological characteristics of time series. Our goal is to identify cell cycle regulated genes in micro array dataset. We construct a point cloud out…

Quantitative Methods · Quantitative Biology 2014-10-03 Saba Emrani , Hamid Krim

Robust clustering from incomplete data is an important topic because, in many practical situations, real data sets are heavy-tailed, asymmetric, and/or have arbitrary patterns of missing observations. Flexible methods and algorithms for…

Methodology · Statistics 2018-11-13 Yuhong Wei , Yang Tang , Paul D. McNicholas

Clustering multivariate time series data is a crucial task in many domains, as it enables the identification of meaningful patterns and groups in time-evolving data. Traditional approaches, such as crisp clustering, rely on the assumption…

Methodology · Statistics 2025-09-05 Ziling Ma , Ángel López-Oriona , Hernando Ombao , Ying Sun

The class of autoregressive (AR) processes is extensively used to model temporal dependence in observed time series. Such models are easily available and routinely fitted using freely available statistical software like R. A potential…

Methodology · Statistics 2020-10-13 Sigrunn H. Sørbye , Pedro G. Nicolau , Håvard Rue

This paper analyzes the role of time-series clustering in traffic matrix (TM) prediction. Traffic flows within a TM often exhibit heterogeneous behavior, which can reduce the effectiveness of global forecasting models that predict all flows…

Networking and Internet Architecture · Computer Science 2026-04-30 Martha Cash , Charlotte Fowler , Alexander M. Wyglinski

This paper describes characteristic features of networks reconstructed from gene expression time series data. Several null models are considered in order to discriminate between informations embedded in the network that are related to real…

Genomics · Quantitative Biology 2015-06-26 D. Remondini , N. Neretti , J. M. Sedivy , C. Franceschi , L. Milanesi , P. Tieri , G. C. Castellani

Clustering is widely used in unsupervised learning to find homogeneous groups of observations within a dataset. However, clustering mixed-type data remains a challenge, as few existing approaches are suited for this task. This study…

Machine Learning · Statistics 2025-11-26 Badih Ghattas , Alvaro Sanchez San-Benito

Non-Gaussian outcomes are often modeled using members of the so-called exponential family. Notorious members are the Bernoulli model for binary data, leading to logistic regression, and the Poisson model for count data, leading to Poisson…

Missing values are largely inevitable in gene expression microarray studies. Data sets often have significant omissions due to individuals dropping out of experiments, errors in data collection, image corruptions, and so on. Missing data…

Quantitative Methods · Quantitative Biology 2018-09-18 Marie Li

We study the problem of constructing coresets for clustering problems with time series data. This problem has gained importance across many fields including biology, medicine, and economics due to the proliferation of sensors facilitating…

Machine Learning · Computer Science 2021-10-29 Lingxiao Huang , K. Sudhir , Nisheeth K. Vishnoi

We analyze gene expression time-series data of yeast S. cerevisiae measured along two full cell-cycles. We quantify these data by using q-exponentials, gene expression ranking and a temporal mean-variance analysis. We construct gene…

Genomics · Quantitative Biology 2016-09-08 Jelena Zivkovic , Bosiljka Tadic , Nikolaus Wick , Stefan Thurner

We propose a novel model-based clustering approach for samples of time series. We assume as a unique commonality that two observations belong to the same group if structural changes in their behaviours happen at the same time. We resort to…

Methodology · Statistics 2024-10-15 Riccardo Corradin , Luca Danese , Wasiur R. KhudaBukhsh , Andrea Ongaro

Researchers often have to deal with heterogeneous population with mixed regression relationships, increasingly so in the era of data explosion. In such problems, when there are many candidate predictors, it is not only of interest to…

Methodology · Statistics 2021-02-05 Yan Li , Chun Yu , Yize Zhao , Robert H. Aseltine , Weixin Yao , Kun Chen

It is well known that correlations in microarray data represent a serious nuisance deteriorating the performance of gene selection procedures. This paper is intended to demonstrate that the correlation structure of microarray data provides…

Applications · Statistics 2007-12-18 Lev Klebanov , Andrei Yakovlev

Mixtures of multivariate normal inverse Gaussian (MNIG) distributions can be used to cluster data that exhibit features such as skewness and heavy tails. However, for cluster analysis, using a traditional finite mixture model framework,…

Methodology · Statistics 2020-05-13 Yuan Fang , Dimitris Karlis , Sanjeena Subedi

We propose a constructive approach to building temporal point processes that incorporate dependence on their history. The dependence is modeled through the conditional density of the duration, i.e., the interval between successive event…

Methodology · Statistics 2025-10-31 Xiaotian Zheng , Athanasios Kottas , Bruno Sansó

With rapid development of techniques to measure brain activity and structure, statistical methods for analyzing modern brain-imaging play an important role in the advancement of science. Imaging data that measure brain function are usually…

Methodology · Statistics 2023-01-05 Haoyi Fu , Lu Tang , Ori Rosen , Alison E. Hipwell , Theodore J. Huppert , Robert T. Krafty

A model-based approach is developed for clustering categorical data with no natural ordering. The proposed method exploits the Hamming distance to define a family of probability mass functions to model the data. The elements of this family…

Methodology · Statistics 2024-07-02 Raffaele Argiento , Edoardo Filippi-Mazzola , Lucia Paci

Finite mixture models have been used for unsupervised learning for some time, and their use within the semi-supervised paradigm is becoming more commonplace. Clickstream data is one of the various emerging data types that demands particular…

Methodology · Statistics 2020-12-17 Michael P. B. Gallaugher , Paul D. McNicholas

We present a novel probabilistic clustering model for objects that are represented via pairwise distances and observed at different time points. The proposed method utilizes the information given by adjacent time points to find the…

Machine Learning · Computer Science 2015-04-16 Julia E. Vogt , Marius Kloft , Stefan Stark , Sudhir S. Raman , Sandhya Prabhakaran , Volker Roth , Gunnar Rätsch