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We investigate membrane-mediated interactions between transmembrane proteins using coarse-grained models. We compare the effective potential of mean force (PMF) between two proteins, which are always aligned parallel to the z-axis of the…

Biological Physics · Physics 2012-04-11 Joerg Neder , Beate West , Peter Nielaba , Friederike Schmid

Nonequilibrium dynamics in correlated materials has attracted attention due to the possibility of characterizing, tuning, and creating complex ordered states. To understand the photoinduced microscopic dynamics, especially the linkage under…

Strongly Correlated Electrons · Physics 2017-12-27 Yao Wang , Martin Claassen , B. Moritz , T. P. Devereaux

In this paper, phase field models are developed for multi-component vesicle membranes with different lipid compositions and membranes with free boundary. These models are used to simulate the deformation of membranes under the elastic…

Biological Physics · Physics 2007-05-23 Xiaoqiang Wang , Qiang Du

The effect of fluctuations on the conductivity of ion channels is investigated. It is shown that modulation of the potential barrier at the selectivity site due to electrostatic amplification of charge fluctuations at the channel mouth…

Biological Physics · Physics 2009-11-13 D. G. Luchinsky , R. Tindjong , I. Kaufman , P. V. E. McClintock , R. S. Eisenberg

We investigate the outflux of ions through the channels in a cell membrane. The channels undergo an open/close cycle according to a periodic schedule. Our study is based both on theoretical considerations relying on homogenization theory,…

Analysis of PDEs · Mathematics 2014-11-21 D. Andreucci , D. Bellaveglia , E. N. M. Cirillo

Many lipid membrane-mediated transport processes--such as mechanically-gated channel activation and solute transport--involve structural and dynamical features on membrane thickness length scales. Most existing membrane models, however,…

Soft Condensed Matter · Physics 2025-08-29 Zachary G. Lipel , Yannick A. D. Omar , Dimitrios Fraggedakis

The organization of live cells into tissues and their subsequent biological function involves inter-cell mechanical interactions, which are mediated by their elastic environment. To model this interaction, we consider cells as spherical…

Soft Condensed Matter · Physics 2024-02-20 Roman Golkov , Yair Shokef

We study fluctuations of particle absorption by a three-dimensional domain with multiple absorbing patches. The domain is in contact with a gas of interacting diffusing particles. This problem is motivated by living cell sensing via…

Statistical Mechanics · Physics 2017-06-28 Tal Agranov , Baruch Meerson

Complex fluids subjected to localized microscopic energy inputs, typical of active microrheology setups, exhibit poorly understood nonequilibrium behaviors because of the intricate self-organization of their mesoscopic constituents. In this…

Statistical Mechanics · Physics 2025-12-15 Danilo Forastiere , Emanuele Locatelli , Gianmaria Falasco , Enzo Orlandini , Marco Baiesi

For many biotechnological applications it would be useful to better understand the effects produced by electric fields on lipid membranes. This review discusses several aspects of the electrostatic properties of a planar lipid membrane with…

Soft Condensed Matter · Physics 2014-11-25 Falko Ziebert , David Lacoste

Multiplicity fluctuations are one of the most crucial observables in the Beam Energy Scan program of the Relativistic Heavy Ion Collider. It is understood that they can be utilized to probe the whereabouts of the critical point on the phase…

Nuclear Theory · Physics 2020-02-12 Hong-Hao Ma , Dan Wen , Kai Lin , Wei-Liang Qian , Bin Wang , Yogiro Hama , Takeshi Kodama

Tissue-scale shape changes are driven by ensembles of intracellular forces. However measuring force in these contexts remains a difficult challenge. Here we perform spectral analysis of transverse fluctuations of cell-cell junctions in…

Soft Condensed Matter · Physics 2026-05-13 Brian Huynh , Shinuo Weng , José Alvarado

Lipid bilayers forming biological membranes are known to behave as viscous 2D fluids on submicrometer scales; usually they contain a large number of active protein inclusions. Recently, it has been shown [Proc. Nat. Acad. Sci. USA 112,…

Soft Condensed Matter · Physics 2016-08-31 Yuki Koyano , Hiroyuki Kitahata , Alexander S. Mikhailov

The recent discovery of electro-active polymers has shown great promises in the field of soft robotics, and was logically followed by experimental, numerical and theoretical developments. Most of these studies were concerned with systems…

Soft Condensed Matter · Physics 2020-12-07 Hadrien Bense , Benoît Roman , Bruno Andreotti

We theoretically investigate the thermally-driven curvature and lipid density fluctuations of a quasi-spherical vesicle, accounting for the dissipation due to monolayer viscosity and intermonolayer friction. The theory predicts that…

Soft Condensed Matter · Physics 2026-05-06 Petia M. Vlahovska , Rony Granek

We use nonequilibrium molecular dynamics simulations to verify recent tube-model predictions that associative polymer networks exhibit broad stretch fluctuations during elongational flow. Simulations further show that these fluctuating…

Soft Condensed Matter · Physics 2025-04-11 Songyue Liu , Thomas C. O'Connor

The space-time dynamics of rigid inhomogeneities (inclusions) free to move in a randomly fluctuating fluid bio-membrane is derived and numerically simulated as a function of the membrane shape changes. Both vertically placed (embedded)…

Computational Physics · Physics 2007-05-23 H. Rafii-Tabar , H. R. Sepangi

Many biological functions rely on the reshaping of cell membranes, in particular into nanotubes, which are covered in vivo by dynamic actin networks. Nanotubes are subject to thermal fluctuations, but the effect of these on cell functions…

Biological Physics · Physics 2020-12-01 Antoine Allard , Fabrice Valentino , Cécile Sykes , Timo Betz , Clément Campillo

Ultrasound is increasingly being used to modulate the properties of biological membranes for applications in drug delivery and neuromodulation. While various studies have investigated the mechanical aspect of the interaction such as…

Soft Condensed Matter · Physics 2018-11-19 Shamit Shrivastava , Robin O. Cleveland , Matthias F. Schneider

We investigate the influence of a self-propelling, out-of-equilibrium active particle on generalized elastic systems, including flexible and semiflexible polymers, fluid membranes, and fluctuating interfaces, while accounting for…

Soft Condensed Matter · Physics 2024-01-25 Alessandro Taloni