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Large language models (LLMs) have been widely adopted in mathematical optimization in scientific scenarios for their extensive knowledge and advanced reasoning capabilities. Existing methods mainly focus on utilizing LLMs to solve…

Optimization and Control · Mathematics 2025-03-18 Qitan Lv , Tianyu Liu , Hong Wang

We consider the problem of learning a high-dimensional graphical model in which certain hub nodes are highly-connected to many other nodes. Many authors have studied the use of an l1 penalty in order to learn a sparse graph in…

Machine Learning · Statistics 2014-08-12 Kean Ming Tan , Palma London , Karthik Mohan , Su-In Lee , Maryam Fazel , Daniela Witten

Partial least squares (PLS) regression combines dimensionality reduction and prediction using a latent variable model. Since partial least squares regression (PLS-R) does not require matrix inversion or diagonalization, it can be applied to…

Methodology · Statistics 2014-08-05 Tzu-Yu Liu , Laura Trinchera , Arthur Tenenhaus , Dennis Wei , Alfred O. Hero

Generalized Linear Models (GLM) form a wide class of regression and classification models, where prediction is a function of a linear combination of the input variables. For statistical inference in high dimension, sparsity inducing…

Machine Learning · Statistics 2022-08-25 Mathurin Massias , Samuel Vaiter , Alexandre Gramfort , Joseph Salmon

Feature selection is a standard approach to understanding and modeling high-dimensional classification data, but the corresponding statistical methods hinge on tuning parameters that are difficult to calibrate. In particular, existing…

Methodology · Statistics 2019-03-01 Wei Li , Johannes Lederer

We propose a new approach to mixed-frequency regressions in a high-dimensional environment that resorts to Group Lasso penalization and Bayesian techniques for estimation and inference. In particular, to improve the prediction properties of…

Econometrics · Economics 2020-06-12 Matteo Mogliani , Anna Simoni

Penalized least squares methods are commonly used for simultaneous estimation and variable selection in high-dimensional linear models. In this paper we compare several prevailing methods including the lasso, nonnegative garrote, and SCAD…

Computation · Statistics 2014-05-09 Ke Zhang , Fan Yin , Shifeng Xiong

Gaussian Mixture Models (GMMs) range among the most frequently used models in machine learning. However, training large, general GMMs becomes computationally prohibitive for datasets that have many data points $N$ of high-dimensionality…

Machine Learning · Statistics 2025-12-12 Sebastian Salwig , Till Kahlke , Florian Hirschberger , Dennis Forster , Jörg Lücke

Inference for spatial generalized linear mixed models (SGLMMs) for high-dimensional non-Gaussian spatial data is computationally intensive. The computational challenge is due to the high-dimensional random effects and because Markov chain…

Computation · Statistics 2018-10-09 Yawen Guan , Murali Haran

Regularization is widely used in statistics and machine learning to prevent overfitting and gear solution towards prior information. In general, a regularized estimation problem minimizes the sum of a loss function and a penalty term. The…

Computation · Statistics 2012-01-18 Hua Zhou , Yichao Wu

We consider the problem of learning a structured multi-task regression, where the output consists of multiple responses that are related by a graph and the correlated response variables are dependent on the common inputs in a sparse but…

Machine Learning · Statistics 2010-05-21 Xi Chen , Seyoung Kim , Qihang Lin , Jaime G. Carbonell , Eric P. Xing

Variable selection is fundamental to high-dimensional statistical modeling. Many variable selection techniques may be implemented by maximum penalized likelihood using various penalty functions. Optimizing the penalized likelihood function…

Statistics Theory · Mathematics 2007-06-13 David R. Hunter , Runze Li

The linear Support Vector Machine (SVM) is a classic classification technique in machine learning. Motivated by applications in modern high dimensional statistics, we consider penalized SVM problems involving the minimization of a…

Machine Learning · Statistics 2021-08-31 Antoine Dedieu , Rahul Mazumder , Haoyue Wang

Generalized linear mixed-effects models (GLMMs) are widely used to analyze grouped and hierarchical data. In a GLMM, each response is assumed to follow an exponential-family distribution where the natural parameter is given by a linear…

Machine Learning · Statistics 2026-04-14 Yuli Slavutsky , Sebastian Salazar , David M. Blei

Kernel Regularized Least Squares (KRLS) is a popular method for flexibly estimating models that may have complex relationships between variables. However, its usefulness to many researchers is limited for two reasons. First, existing…

Machine Learning · Statistics 2023-09-12 Qing Chang , Max Goplerud

The generalized linear mixed model (GLMM) is widely used for analyzing correlated data, particularly in large-scale biomedical and social science applications. Scalable Bayesian inference for GLMMs is challenging because the marginal…

Computation · Statistics 2026-01-07 Samuel I. Berchuck , Youngsoo Baek , Felipe A. Medeiros , Andrea Agazzi

Mixtures of matrix Gaussian distributions provide a probabilistic framework for clustering continuous matrix-variate data, which are becoming increasingly prevalent in various fields. Despite its widespread adoption and successful…

Computation · Statistics 2023-07-21 Andrea Cappozzo , Alessandro Casa , Michael Fop

We propose the Lasso Weighted $k$-means ($LW$-$k$-means) algorithm as a simple yet efficient sparse clustering procedure for high-dimensional data where the number of features ($p$) can be much larger compared to the number of observations…

Machine Learning · Statistics 2019-03-26 Saptarshi Chakraborty , Swagatam Das

High resolution microarrays and second-generation sequencing platforms are powerful tools to investigate genome-wide alterations in DNA copy number, methylation and gene expression associated with a disease. An integrated genomic profiling…

Applications · Statistics 2013-04-22 Ronglai Shen , Sijian Wang , Qianxing Mo

The Gaussian Process Latent Variable Model (GP-LVM) is a non-linear probabilistic method of embedding a high dimensional dataset in terms low dimensional `latent' variables. In this paper we illustrate that maximum a posteriori (MAP)…

Machine Learning · Statistics 2013-07-02 James Barrett , Anthony C. C. Coolen
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