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Related papers: Viscosity and Diffusion: Crowding and Salt Effects…

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Stochasticity plays a fundamental role in various biochemical processes, such as cell regulatory networks and enzyme cascades. Isothermal, well-mixed systems can be modelled as Markov processes, typically simulated using the Gillespie…

Molecular Networks · Quantitative Biology 2016-10-12 Andrew Duncan , Radek Erban , Konstantinos Zygalakis

We report on a comprehensive theory-simulation-experimental study of collective and self-diffusion in suspensions of charge-stabilized colloidal spheres. In simulation and theory, the spheres interact by a hard-core plus screened Coulomb…

Soft Condensed Matter · Physics 2018-04-13 Adolfo J. Banchio , Marco Heinen , Peter Holmqvist , Gerhard Nägele

The Enskog kinetic theory is applied to compute the mean square displacement of intruders immersed in a granular gas of smooth inelastic hard spheres (grains). Both species (intruders and grains) are surrounded by an interstitial molecular…

Soft Condensed Matter · Physics 2023-08-30 Rubén Gómez González , Enrique Abad , Santos Bravo Yuste , Vicente Garzó

In recent years, diffusion models trained on equilibrium molecular distributions have proven effective for sampling biomolecules. Beyond direct sampling, the score of such a model can also be used to derive the forces that act on molecular…

Machine Learning · Computer Science 2026-01-15 Michael Plainer , Hao Wu , Leon Klein , Stephan Günnemann , Frank Noé

The vibrational anomalies of glasses, in particular the boson peak, are addressed from the standpoint of heterogeneous elasticity, namely the spatial fluctuations of elastic constants caused by the structural disorder of the amorphous…

Disordered Systems and Neural Networks · Physics 2020-09-15 Walter Schirmacher , Giancarlo Ruocco

In this letter, following an extensive experimental validation, we perform constant-volume shearing simulations of non-Brownian granular suspensions using the discrete element method coupled with the lattice Boltzmann method. We choose a…

Soft Condensed Matter · Physics 2023-07-18 Zaohui Zhang , Teng Man , Herbert E. Huppert , Sergio Andres Galindo-Torres

Enormous enhancement in the viscosity of a liquid near its glass transition is generally connected to the growing many-body static correlations near the transition, often coined as `amorphous ordering'. Estimating the length scales of such…

We use X-ray imaging to study viscous resuspension. In a Taylor-Couette geometry, we shear an initially settled layer of spherical glass particles immersed in a Newtonian fluid and measure the local volume fraction profiles. In this…

Soft Condensed Matter · Physics 2019-12-19 Brice Saint-Michel , Sébastien Manneville , Steven Meeker , Guillaume Ovarlez , Hugues Bodiguel

Glycerol acts as a natural cryoprotectant by depressing the temperature of ice nucleation and slowing down the dynamics of water mixtures. In this work we characterize dynamics -- diffusion, viscosity, and hydrogen-bond dynamics -- as well…

The interest in the extracellular vesicles (EVs) is rapidly growing as they became reliable biomarkers for many diseases. For this reason, fast and accurate techniques of EVs size characterization are the matter of utmost importance. One…

Biological Physics · Physics 2018-03-26 M. Majka , M. Durak-Kozica , A. Kamińska , A. Opalińska , M. Szczęch , E. Stępień

Supercooled liquids exhibit complicated dynamical behaviors: At the microscopic level, the dynamics is heterogeneous spatially, known as dynamic heterogeneity. At the macroscopic level, the shear viscosity $\eta$ decreases as shear rate…

Soft Condensed Matter · Physics 2025-09-01 Ke-Qi Zeng , Dong-Xu Yu , Zhe Wang

In this paper, we propose a Generalized Langevin Equation (GLE)-based model to describe the lateral diffusion of a protein in a lipid bilayer. The memory kernel is represented in terms of a viscous (instantaneous) and an elastic (non…

Biological Physics · Physics 2021-11-24 Loris Di Cairano , Benjamin Stamm , Vania Calandrini

Self Consistent Normal Mode Analysis (SCNMA) is applied to heme c type cytochrome f to study temperature dependent protein motion. Classical Normal Mode Analysis (NMA) assumes harmonic behavior and the protein Mean Square Displacement (MSD)…

Biological Physics · Physics 2013-05-29 Jianguang Guo , Timo Budarz , Joshua M. Ward , Earl W. Prohofsky

We study the dynamics of hydration water/protein association in folded proteins, using lysozyme and myoglobin as examples. Extensive molecular dynamics simulations are performed to identify underlying mechanisms of the dynamical transition…

Soft Condensed Matter · Physics 2015-05-13 J. Servantie , C. Atilgan , A. R. Atilgan

Monoclonal antibodies are among the most promising therapeutic agents in modern medicine, yet their formulation into high-concentration solutions for subcutaneous self-administration poses a major challenge. A key obstacle is the marked…

Soft Condensed Matter · Physics 2025-01-14 Fabrizio Camerin , Marco Polimeni , Anna Stradner , Emanuela Zaccarelli , Peter Schurtenberger

We investigated the viscoelastic response of model interphase chromosomes by tracking the three-dimensional motion of hundreds of dispersed Brownian particles of sizes ranging from the thickness of the chromatin fiber up to slightly above…

Biomolecules · Quantitative Biology 2015-01-06 Manon Valet , Angelo Rosa

Phase change materials are exploited in non-volatile electronic memories and photonic devices that rely on a fast and reversible transformation between the amorphous and crystalline phase upon heating. The recrystallization of the amorphous…

Disordered Systems and Neural Networks · Physics 2025-10-24 Simone Marcorini , Rocco Pomodoro , Omar Abou El Kheir , Marco Bernasconi

The first paper of this series [J. Chem. Phys. 158, 034103 (2023)] demonstrated that excess entropy scaling holds for both fine-grained and corresponding coarse-grained (CG) systems. Despite its universality, a more exact determination of…

Chemical Physics · Physics 2023-01-18 Jaehyeok Jin , Kenneth S. Schweizer , Gregory A. Voth

Diffusion models have emerged as a powerful class of generative models by learning to iteratively reverse the noising process. Their ability to generate high-quality samples has extended beyond high-dimensional image data to other complex…

Machine Learning · Computer Science 2025-09-03 Srinivas Anumasa , Barath Chandran. C , Tingting Chen , Dianbo Liu

A discretization scheme is introduced for a set of convection-diffusion equations with a non-linear reaction term, where the convection velocity is constant for each reactant. This constancy allows a transformation to new spatial variables,…

Computational Physics · Physics 2017-09-19 József Vass , Sergey N. Krylov