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Understanding how age-specific social contact patterns and susceptibility influence infectious disease transmission is crucial for accurate epidemic modeling. This study presents an eigenvector-based sensitivity analysis framework to…

Populations and Evolution · Quantitative Biology 2025-11-21 Evans Kiptoo Korir , Zsolt Vizi

The coronavirus disease 2019 (COVID-19) pandemic has quickly become a global public health crisis unseen in recent years. It is known that the structure of the human contact network plays an important role in the spread of transmissible…

Social and Information Networks · Computer Science 2020-10-08 Abby Leung , Xiaoye Ding , Shenyang Huang , Reihaneh Rabbany

The course of an epidemic is not only shaped by infection transmission over face-to-face contacts, but also by preventive behaviour caused by risk perception and social interactions. This study explores the dynamics of coupled awareness and…

Physics and Society · Physics 2025-02-24 Tim Van Wesemael , Luis E. C. Rocha , Jan M. Baetens

To better predict the dynamics of epidemics such as COVID-19, it is important not only to investigate the network of local and long-range contagious contacts but also to understand the temporal dynamics of infectiousness and detectable…

Populations and Evolution · Quantitative Biology 2025-09-03 Miguel A. Cajahuanca Ricaldi , Yaroslav Ispolatov

Most real-world networks are not isolated. In order to function fully, they are interconnected with other networks, and this interconnection influences their dynamic processes. For example, when the spread of a disease involves two species,…

Physics and Society · Physics 2013-08-09 Huijuan Wang , Qian Li , Gregorio D'Agostino , Shlomo Havlin , H. Eugene Stanley , Piet Van Mieghem

Respondent-Driven Sampling (RDS) is an approach to sampling design and inference in hard-to-reach human populations. Typically, a sampling frame is not available, and population members are difficult to identify or recruit from broader…

Methodology · Statistics 2012-09-28 Mark S. Handcock , Krista J. Gile , Corinne M. Mar

This research gives a thorough examination of an HIV infection model that includes quiescent cells and immune response dynamics in the host. The model, represented by a system of ordinary differential equations, captures the complex…

Populations and Evolution · Quantitative Biology 2025-03-04 Ibrahim Nali , Attila Dénes , Abdessamad Tridane , Xueyong Zhou

The initial phase of an epidemic is often characterized by an exponential increase in the number of infected individuals. In this paper, we predict the exponential spreading rate of an epidemic on a complex network. We first find an…

Physics and Society · Physics 2025-04-21 Samuel Cure , Florian G. Pflug , Simone Pigolotti

Empirical studies suggest that contact patterns follow heterogeneous inter-event times, meaning that intervals of high activity are followed by periods of inactivity. Combined with birth and death of individuals, these temporal constraints…

Physics and Society · Physics 2013-03-25 Luis Enrique Correa Rocha , Vincent D. Blondel

Respondent-driven sampling (RDS) is a procedure to sample from hard-to-reach populations. It has been widely used in several countries, especially in the monitoring of HIV/AIDS and other sexually transmitted infections. Hard-to-reach…

Applications · Statistics 2012-06-26 Leonardo S. Bastos , Adriana A. Pinho , Claudia Codeço , Francisco I. Bastos

Network-based epidemic models have been extensively employed to understand the spread of infectious diseases, but have generally overlooked the fact that most realistic networks are dynamical rather than static. In this paper, we study a…

Physics and Society · Physics 2019-02-19 Xiao-Long Peng , Ze-Qiong Zhang , Junyuan Yang , Zhen Jin

We consider the standard three-component differential equation model for the growth of an HIV virion population in an infected host in the absence of drug therapy. The dynamical properties of the model are determined by the set of values of…

Populations and Evolution · Quantitative Biology 2011-07-19 Henry C Tuckwell , Patrick D Shipman

The spread of infectious diseases crucially depends on the pattern of contacts among individuals. Knowledge of these patterns is thus essential to inform models and computational efforts. Few empirical studies are however available that…

HIV-1 can disseminate between susceptible cells by two mechanisms: cell-free infection following fluid-phase diffusion of virions and by highly-efficient direct cell-to-cell transmission at immune cell contacts. The contribution of this…

Populations and Evolution · Quantitative Biology 2024-01-02 Changwang Zhang , Shi Zhou , Elisabetta Groppelli , Pierre Pellegrino , Ian Williams , Persephone Borrow , Benjamin M. Chain , Clare Jolly

In this paper, we study the trajectory of a classic SIR epidemic on a family of dynamic random graphs of fixed size, whose set of edges continuously evolves over time. We set general infection and recovery times, and start the epidemic from…

Probability · Mathematics 2025-01-17 Marta Milewska , Remco van der Hofstad , Bert Zwart

We propose a mixed-methods approach to understanding the human infrastructure underlying StreetNet (SNET), a distributed, community-run intranet that serves as the primary 'Internet' in Havana, Cuba. We bridge ethnographic studies and the…

Social and Information Networks · Computer Science 2020-04-28 Abigail Z. Jacobs , Michaelanne Dye

Social contact studies, investigating social contact patterns in a population sample, have been an important contribution for epidemic models to better fit real life epidemics. A contact matrix $M$, having the \emph{mean} number of contacts…

Populations and Evolution · Quantitative Biology 2024-08-15 Tom Britton , Frank Ball

We formulate and analyze a novel hypothesis testing problem for inferring the edge structure of an infection graph. In our model, a disease spreads over a network via contagion or random infection, where the random variables governing the…

Statistics Theory · Mathematics 2020-05-05 Justin Khim , Po-Ling Loh

HIV transmission within serodiscordant couples remains a significant public health challenge, particularly in sub-Saharan Africa. Estimating the rate of such infection, alongside the rates of introduction of infection from outside the…

Applications · Statistics 2026-02-05 Irene García Muñoz , Ian Hall , Thomas House

Understanding and predicting outbreaks of contagious diseases are crucial to the development of society and public health, especially for underdeveloped countries. However, challenging problems are encountered because of complex epidemic…

Populations and Evolution · Quantitative Biology 2022-02-15 Ruiqi Li , Wenxu Wang , Zengru Di
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