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Photoacoustic imaging (PAI) represents an innovative biomedical imaging modality that harnesses the advantages of optical resolution and acoustic penetration depth while ensuring enhanced safety. Despite its promising potential across a…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Lei Wang , Weiming Zeng , Kai Long , Hongyu Chen , Rongfeng Lan , Li Liu , Wai Ting Siok , Nizhuan Wang

Photoacoustic tomography is a hybrid biomedical technology, which combines the advantages of acoustic and optical imaging. However, for the conventional image reconstruction method, the image quality is affected obviously by artifacts under…

Image and Video Processing · Electrical Eng. & Systems 2024-06-26 Bowei Yao , Yi Zeng , Haizhao Dai , Qing Wu , Youshen Xiao , Fei Gao , Yuyao Zhang , Jingyi Yu , Xiran Cai

Purpose: Photoacoustic tomography (PAT) is a novel imaging technique that can spatially resolve both morphological and functional tissue properties, such as the vessel topology and tissue oxygenation. While this capacity makes PAT a…

Photoacoustic image reconstruction often assumes that the restriction of the acoustic pressure on the detection surface is given. However, commonly used detectors often have a certain directivity and frequency dependence, in which case the…

Numerical Analysis · Mathematics 2020-01-08 Gerhard Zangerl , Sunghwan Moon , Markus Haltmeier

The attenuation of ultrasound waves in photoacoustic and thermoacoustic imaging presents an important drawback in the applicability of these modalities. This issue has been addressed previously in the applied and theoretical literature, and…

Analysis of PDEs · Mathematics 2021-09-15 Benjamin Palacios

We study the inverse source problem in photoacoustic tomography (PAT) for mixed data, which denote a weighted linear combination of the acoustic pressure and its normal derivative on an observation surface. We consider in particular the…

Analysis of PDEs · Mathematics 2022-07-06 Florian Dreier , Markus Haltmeier

Photoacoustic tomography (PAT) is a hybrid medical imaging technique that offer high contrast and a high spatial resolution. One challenging mathematical problem associated with PAT is reconstructing the initial pressure of the wave…

Numerical Analysis · Mathematics 2024-07-16 Gyeongha Hwang , Gihyeon Jeon , Sunghwan Moon , Dabin Park

In this article, we study several reconstruction methods for the inverse source problem of photoacoustic tomography (PAT) with spatially variable sound speed and damping. The backbone of these methods is the adjoint operators, which we…

Analysis of PDEs · Mathematics 2018-08-21 Linh V. Nguyen , Markus Haltmeier

Photoacoustic Tomography (PAT) is an emerging biomedical "imaging from coupled physics" technique, in which the image contrast is due to optical absorption, but the information is carried to the surface of the tissue as ultrasound pulses.…

Numerical Analysis · Mathematics 2016-11-03 Simon R. Arridge , Marta M. Betcke , Ben T. Cox , Felix Lucka , Brad E. Treeby

Photoacoustic tomography (PAT) is a newly emerged imaging modality which enables both high optical contrast and acoustic depth of penetration. Reconstructing images of photoacoustic tomography from limited amount of senser data is among one…

Computer Vision and Pattern Recognition · Computer Science 2023-06-27 Shangqing Tong , Hengrong Lan , Liming Nie , Jianwen Luo , Fei Gao

This is the manuscript of the chapter for a planned Handbook of Mathematical Methods in Imaging that surveys the mathematical models, problems, and algorithms of the Thermoacoustic (TAT) and Photoacoustic (PAT) Tomography. TAT and PAT…

Analysis of PDEs · Mathematics 2011-10-04 Peter Kuchment , Leonid Kunyansky

Photoacoustic tomography is an emerging medical imaging technology whose primary aim is to map the high-contrast optical properties of biological tissues by leveraging high-resolution ultrasound measurements. Mathematically, this can be…

Analysis of PDEs · Mathematics 2025-02-14 Alessandro Felisi

We investigate resolution in photoacoustic tomography (PAT). Using Shannon theory, we investigate the theoretical resolution limit of sparse view PAT theoretically, and empirically demonstrate that all reconstruction methods used exceed…

Numerical Analysis · Mathematics 2023-10-17 Markus Haltmeier , Daniel Obmann , Karoline Felbermayer , Florian Hinterleitner , Peter Burgholzer

Optoacoustic tomography (OAT), also known as photoacoustic tomography, is a rapidly emerging hybrid imaging technique that possesses great potential for a wide range of biomedical imaging applications. In OAT, a laser is employed to…

Medical Physics · Physics 2016-12-21 Yang Lou , Kun Wang , Alexander. A. Oraevsky , Mark. A. Anastasio

Applying standard algorithms to sparse data problems in photoacoustic tomography (PAT) yields low-quality images containing severe under-sampling artifacts. To some extent, these artifacts can be reduced by iterative image reconstruction…

Numerical Analysis · Mathematics 2024-12-20 Stephan Antholzer , Johannes Schwab , Robert Nuster , Markus Haltmeier

Photoacoustic computed tomography (PACT) is an emerging computed imaging modality that exploits optical contrast and ultrasonic detection principles to form images of the absorbed optical energy density within tissue. When the imaging…

Medical Physics · Physics 2016-11-15 Qiwei Sheng , Kun Wang , Thomas P. Matthews , Jun Xia , Liren Zhu , Lihong V. Wang , Mark A. Anastasio

Photoacoustic tomography is a hybrid imaging technique that combines high optical tissue contrast with high ultrasound resolution. Direct reconstruction methods such as filtered backprojection, time reversal and least squares suffer from…

Photoacoustic imaging (PAI) is a non-invasive imaging modality that detects the ultrasound signal generated from tissue with light excitation. Photoacoustic computed tomography (PACT) uses unfocused large-area light to illuminate the target…

Image and Video Processing · Electrical Eng. & Systems 2022-04-13 Hengrong Lan , Jiali Gong , Fei Gao

Two-photon absorption photoacoustic tomography (TP-PAT) is a recent hybrid imaging modality that aims at reconstructing two-photon absorption properties of heterogeneous media from measured ultrasound signals generated by the photoacoustic…

Medical Physics · Physics 2018-03-14 Patrick Bardsley , Kui Ren , Rongting Zhang

In photoacoustic tomography (PAT), the computation of the initial pressure distribution within an object from its time-dependent boundary measurements over time is considered. This problem can be approached from two well-established points…

Numerical Analysis · Mathematics 2025-07-04 Jaakko Kultima , Ronny Ramlau , Teemu Sahlström , Tanja Tarvainen