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We present a method that compares the protein interaction networks of two species to detect functionally similar (conserved) protein modules between them. The method is based on an algorithm we developed to identify matching subgraphs…

Molecular Networks · Quantitative Biology 2007-05-23 Manikandan Narayanan , Richard M. Karp

Network data are increasingly collected along with other variables of interest. Our motivation is drawn from neurophysiology studies measuring brain connectivity networks for a sample of individuals along with their membership to a low or…

Methodology · Statistics 2018-09-11 Daniele Durante , David B. Dunson

The ability to represent and compare machine learning models is crucial in order to quantify subtle model changes, evaluate generative models, and gather insights on neural network architectures. Existing techniques for comparing data…

It is well-known that biological and social interaction networks have a varying degree of redundancy, though a consensus of the precise cause of this is so far lacking. In this paper, we introduce a topological redundancy measure for…

First we shortly review the different kinds of network modelling methods for systems biology with an emphasis on the different subtypes of logical models, which we review in more detail. Then we show the advantages of Boolean networks…

Molecular Networks · Quantitative Biology 2020-03-03 Gerhard Mayer

The increasing availability of multiple network data has highlighted the need for statistical models for heterogeneous populations of networks. A convenient framework makes use of metrics to measure similarity between networks. In this…

Methodology · Statistics 2026-03-09 Francesco Barile , Simón Lunagómez , Bernardo Nipoti

Most social, technological and biological networks are embedded in a finite dimensional space, and the distance between two nodes influences the likelihood that they link to each other. Indeed, in social systems, the chance that two…

Physics and Society · Physics 2018-06-27 Paul Balister , Chaoming Song , Oliver Riordan , Bela Bollobas , Albert-Laszlo Barabasi

More than ever, today we are left with the abundance of molecular data outpaced by the advancements of the phylogenomic methods. Especially in the case of presence of many genes over a set of species under the phylogeny question, more…

Applications · Statistics 2021-11-29 Ali Amiryousefi

The \textit{biharmonic distance} (BD) is a fundamental metric that measures the distance of two nodes in a graph. It has found applications in network coherence, machine learning, and computational graphics, among others. In spite of BD's…

Social and Information Networks · Computer Science 2024-08-27 Changan Liu , Ahad N. Zehmakan , Zhongzhi Zhang

It has been shown that many complex networks shared distinctive features, which differ in many ways from the random and the regular networks. Although these features capture important characteristics of complex networks, their applicability…

Physics and Society · Physics 2009-11-11 Chang-Yong Lee , Sunghwan Jung

Common measures of neural representational (dis)similarity are designed to be insensitive to rotations and reflections of the neural activation space. Motivated by the premise that the tuning of individual units may be important, there has…

Machine Learning · Computer Science 2023-11-17 Meenakshi Khosla , Alex H. Williams

Most real-world networks are not isolated. In order to function fully, they are interconnected with other networks, and this interconnection influences their dynamic processes. For example, when the spread of a disease involves two species,…

Physics and Society · Physics 2013-08-09 Huijuan Wang , Qian Li , Gregorio D'Agostino , Shlomo Havlin , H. Eugene Stanley , Piet Van Mieghem

Screening mammograms is the gold standard for detecting breast cancer early. While a good amount of work has been performed on mammography image classification, especially with deep neural networks, there has not been much exploration into…

Machine Learning · Computer Science 2020-08-14 Anika Tabassum , Naimul Khan

Trees have long been used as a graphical representation of species relationships. However complex evolutionary events, such as genetic reassortments or hybrid speciations which occur commonly in viruses, bacteria and plants, do not fit into…

Populations and Evolution · Quantitative Biology 2017-07-24 Sebastien Roch , Kun-Chieh Wang

This paper is Part II of a two-part series devoting to the study of systematic measures in a complex bio-network modeled by a system of ordinary differential equations. In this part, we quantify several systematic measures of a biological…

Probability · Mathematics 2016-06-13 Yao Li , Yingfei Yi

Inferring the phylogenetic relationships among a sample of organisms is a fundamental problem in modern biology. While distance-based hierarchical clustering algorithms achieved early success on this task, these have been supplanted by…

Machine Learning · Computer Science 2025-12-03 Benjamin K. Rosenzweig , Matthew W. Hahn

How do social networks differ across platforms? How do information networks change over time? Answering questions like these requires us to compare two or more graphs. This task is commonly treated as a measurement problem, but numerical…

Social and Information Networks · Computer Science 2022-05-10 Corinna Coupette , Jilles Vreeken

Graph theoretical approach has proved an effective tool to understand, characterize and quantify the complex brain network. However, much less attention has been paid to methods that quantitatively compare two graphs, a crucial issue in the…

Neurons and Cognition · Quantitative Biology 2019-08-29 Ahmad Mheich , Fabrice Wendling , Mahmoud Hassan

Comparing weighted networks in neuroscience is hard, because the topological properties of a given network are necessarily dependent on the number of edges of that network. This problem arises in the analysis of both weighted and unweighted…

Applications · Statistics 2014-03-28 Cedric E. Ginestet , Arnaud P. Fournel , Andrew Simmons

Discovering community structure in complex networks is a mature field since a tremendous number of community detection methods have been introduced in the literature. Nevertheless, it is still very challenging for practioners to determine…

Social and Information Networks · Computer Science 2021-04-15 Vinh-Loc Dao , Cécile Bothorel , Philippe Lenca