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We present a framework for discriminative sequence classification where the learner works directly in the high dimensional predictor space of all subsequences in the training set. This is possible by employing a new coordinate-descent…

Machine Learning · Computer Science 2010-08-04 Georgiana Ifrim , Carsten Wiuf

We tackle the problem of unsupervised visual descriptors compression, which is a key ingredient of large-scale image retrieval systems. While the deep learning machinery has benefited literally all computer vision pipelines, the existing…

Machine Learning · Computer Science 2019-08-13 Stanislav Morozov , Artem Babenko

The growing volume of scientific simulation data presents a significant challenge for storage and transfer. Error-bounded lossy compression has emerged as a critical solution for mitigating these challenges, providing a means to reduce data…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-01-29 Arshan Khan , Rohit Deshmukh , Ben O'Neill

In the supervised learning domain, considering the recent prevalence of algorithms with high computational cost, the attention is steering towards simpler, lighter, and less computationally extensive training and inference approaches. In…

Machine Learning · Computer Science 2022-09-02 Antonello Rosato , Massimo Panella , Denis Kleyko

The vast parallelism, exceptional energy efficiency and extraordinary information inherent in DNA molecules are being explored for computing, data storage and cryptography. DNA cryptography is a emerging field of cryptography. In this paper…

Cryptography and Security · Computer Science 2011-01-14 D. Prabhu , M. Adimoolam

We study the amount of reliable information that can be stored in a DNA-based storage system composed of short DNA molecules. In this regime, Shomorony and Heckel (2022) put forward a conjecture on the scaling of the number of information…

Information Theory · Computer Science 2025-11-19 Ran Tamir , Nir Weinberger , Albert Guillén i Fàbregas

DNA is not only the genetic material of life, but also a favorable material for a new computing model. Various research works based on DNA computing have been carried out in recent years. DNA sequence design is the foundation of such…

Emerging Technologies · Computer Science 2023-11-10 Yao Yao , Xun Zhang , Xin Liu , Yuan Liu , Xiaokang Zhang , Qiang Zhang

This paper describes a method to efficiently retrieve protein database sequences similar to a query sequence, while allowing for significant numbers of mutations. We call this method SEQR for SEQuence Retrieval. This approach increases the…

Genomics · Quantitative Biology 2018-11-05 David I. Hurwitz , Lianyi Han , Lewis Y. Geer

Encoding data as a set of unordered strings is receiving great attention as it captures one of the basic features of DNA storage systems. However, the challenge of constructing optimal redundancy codes for this channel remained elusive. In…

Information Theory · Computer Science 2023-08-16 Jin Sima , Netanel Raviv , Jehoshua Bruck

Compression refers to encoding data using bits, so that the representation uses as few bits as possible. Compression could be lossless: i.e. encoded data can be recovered exactly from its representation) or lossy where the data is…

Information Theory · Computer Science 2012-10-19 Narayana Santhanam , Dharmendra Modha

Due to their sequential nature, traditional DNA synthesis methods are expensive in terms of time and resources. They also fabricate multiple copies of the same strand, introducing redundancy. This redundancy can be leveraged to enhance the…

Information Theory · Computer Science 2025-10-29 Frederik Walter , Yonatan Yehezkeally

Exponential increase of data has motivated advances of data storage technologies. As a promising storage media, DeoxyriboNucleic Acid (DNA) storage provides a much higher data density and superior durability, compared with state-of-the-art…

Information Theory · Computer Science 2023-11-14 Luping Xiang , Qiang Liu , Sirong Chen , Kang Yan , Wenfeng Wu , Kun Yang

We present a parallel algorithm and scalable implementation for genome analysis, specifically the problem of finding overlaps and alignments for data from "third generation" long read sequencers. While long sequences of DNA offer enormous…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-01-29 Marquita Ellis , Giulia Guidi , Aydın Buluç , Leonid Oliker , Katherine Yelick

Due to its longevity and enormous information density, DNA is an attractive medium for archival storage. In this work, we study the fundamental limits and trade-offs of DNA-based storage systems by introducing a new channel model, which we…

Information Theory · Computer Science 2020-01-20 Ilan Shomorony , Reinhard Heckel

In this paper, we propose a novel iterative encoding algorithm for DNA storage to satisfy both the GC balance and run-length constraints using a greedy algorithm. DNA strands with run-length more than three and the GC balance ratio far from…

Information Theory · Computer Science 2023-01-04 Seong-Joon Park , Yongwoo Lee , Jong-Seon No

People tend to store a lot of files inside theirs storage. When the storage nears it limit, they then try to reduce those files size to minimum by using data compression software. In this paper we propose a new algorithm for data…

Data Structures and Algorithms · Computer Science 2012-09-06 I. Made Agus Dwi Suarjaya

The synthesis of DNA strands remains the most costly part of the DNA storage system. Thus, to make DNA storage system more practical, the time and materials used in the synthesis process have to be optimized. We consider the most common…

Information Theory · Computer Science 2023-05-15 Johan Chrisnata , Han Mao Kiah , Van Long Phuoc Pham

As deep neural networks (DNNs) grow in complexity and size, the resultant increase in communication overhead during distributed training has become a significant bottleneck, challenging the scalability of distributed training systems.…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-02-13 Haoyu Li , Yuchen Xu , Jiayi Chen , Rohit Dwivedula , Wenfei Wu , Keqiang He , Aditya Akella , Daehyeok Kim

In scientific simulations, observations, and experiments, the cost of transferring data to and from disk and across networks has become a significant bottleneck that particularly impacts subsequent data analysis and visualization. To…

Databases · Computer Science 2023-08-24 Victor A. P. Magri , Peter Lindstrom

The Jaccard similarity index is an important measure of the overlap of two sets, widely used in machine learning, computational genomics, information retrieval, and many other areas. We design and implement SimilarityAtScale, the first…

Computational Engineering, Finance, and Science · Computer Science 2020-11-12 Maciej Besta , Raghavendra Kanakagiri , Harun Mustafa , Mikhail Karasikov , Gunnar Rätsch , Torsten Hoefler , Edgar Solomonik
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