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Generating molecular graphs is crucial in drug design and discovery but remains challenging due to the complex interdependencies between nodes and edges. While diffusion models have demonstrated their potentiality in molecular graph design,…

Machine Learning · Computer Science 2024-11-11 Xiaoyang Hou , Tian Zhu , Milong Ren , Dongbo Bu , Xin Gao , Chunming Zhang , Shiwei Sun

A simple algorithm for constructing an effective traffic model is presented. The algorithm uses statistically well-defined quantities extracted from the flow-density plot, and the resulting effective model naturally captures and predicts…

Adaptation and Self-Organizing Systems · Physics 2014-12-16 Bo Yang , Christopher Monterola

Multivariate time series forecasting is a challenging task because the data involves a mixture of long- and short-term patterns, with dynamic spatio-temporal dependencies among variables. Existing graph neural networks (GNN) typically model…

Machine Learning · Computer Science 2021-12-08 Zhuoling Li , Gaowei Zhang , Lingyu Xu , Jie Yu

We analyse a dynamic control problem for scalar reaction-diffusion equations, focusing on the emulation of pattern formation through the selection of appropriate active controls. While boundary controls alone prove inadequate for…

Optimization and Control · Mathematics 2024-07-26 Domènec Ruiz-Balet , Enrique Zuazua

Phenotypical variability in the absence of genetic variation often reflects complex energetic landscapes associated with underlying gene regulatory networks (GRNs). In this view, different phenotypes are associated with alternative states…

Molecular Networks · Quantitative Biology 2018-06-27 M. Ali Al-Radhawi , Domitilla Del Vecchio , Eduardo D. Sontag

Retrosynthesis, which aims to identify viable synthetic pathways for target molecules by decomposing them into simpler precursors, is often treated as a search problem. However, its complexity arises from multi-branched tree-structured…

Artificial Intelligence · Computer Science 2025-11-25 Chengyang Tian , Yuhang Chang , Yangpeng Zhang , Yang Liu

Network sampling is integral to the analysis of social, information, and biological networks. Since many real-world networks are massive in size, continuously evolving, and/or distributed in nature, the network structure is often sampled in…

Social and Information Networks · Computer Science 2012-11-16 Nesreen K. Ahmed , Jennifer Neville , Ramana Kompella

Probabilistic message-passing algorithms are developed for routing transmissions in multi-wavelength optical communication networks, under node and edge-disjoint routing constraints and for various objective functions. Global routing…

Physics and Society · Physics 2022-04-25 Yi-Zhi Xu , Ho Fai Po , Chi Ho Yeung , David Saad

Using the growing volumes of vehicle trajectory data, it becomes increasingly possible to capture time-varying and uncertain travel costs in a road network, including travel time and fuel consumption. The current paradigm represents a road…

Databases · Computer Science 2015-12-07 Jian Dai , Bin Yang , Chenjuan Guo , Christian S. Jensen

The pathway is a biological term that refers to a series of interactions between molecules in a cell that causes a certain product or a change in the cell. Pathway analysis is a powerful method for gene expression analysis. Through pathway…

Data Structures and Algorithms · Computer Science 2022-01-11 Lingran Xiao , Yanfei Wang , Shiying Li , Lingxi Chen , Shuaicheng Li

In this article, we investigate an artificial traffic model on scale-free networks. Instead of using the routing strategy of the shortest path, a generalized routing algorithm is introduced to improve the transportation throughput, which is…

Physics and Society · Physics 2007-05-23 Shi-Min Cai , Gang Yan , Tao Zhou , Pei-Ling Zhou , Zhong-Qian Fu , Bing-Hong Wang

Graphs are essential representations of many real-world data such as social networks. Recent years have witnessed the increasing efforts made to extend the neural network models to graph-structured data. These methods, which are usually…

Machine Learning · Computer Science 2018-11-07 Yao Ma , Ziyi Guo , Zhaochun Ren , Eric Zhao , Jiliang Tang , Dawei Yin

Modern processing networks often consist of heterogeneous servers with widely varying capabilities, and process job flows with complex structure and requirements. A major challenge in designing efficient scheduling policies in these…

Probability · Mathematics 2016-10-13 Ramtin Pedarsani , Jean Walrand , Yuan Zhong

This paper introduces a new macroscopic perspective for simulating transportation networks. The idea is to look at the network as connected nodes. Each node sends an information package to its neighbors. Basically, the information package…

Dynamical Systems · Mathematics 2024-07-19 Omar Mansour , Tomer Toledo , Shadi Haj-Yahia , Wafa Elias

We introduce a new approach to model and analyze \emph{Mobility}. It is fully based on discrete mathematics and yields a class of mobility models, called the \emph{Markov Trace} Model. This model can be seen as the discrete version of the…

Discrete Mathematics · Computer Science 2010-02-05 Andrea Clementi , Angelo Monti , Riccardo Silvestri

The fast evolving nature of modern cyber threats and network monitoring needs calls for new, "software-defined", approaches to simplify and quicken programming and deployment of online (stream-based) traffic analysis functions. StreaMon is…

Networking and Internet Architecture · Computer Science 2013-11-12 Giuseppe Bianchi , Marco Bonola , Giulio Picierro , Salvatore Pontarelli , Marco Monaci

Mobile robots frequently navigate on roadmaps, i.e., graphs where edges represent safe motions, in applications such as healthcare, hospitality, and warehouse automation. Often the environment is quasi-static, i.e., it is sufficient to…

Robotics · Computer Science 2025-04-25 Christian Henkel , Marc Toussaint , Wolfgang Hönig

The paper presents an exponential pheromone deposition approach to improve the performance of classical Ant System algorithm which employs uniform deposition rule. A simplified analysis using differential equations is carried out to study…

Artificial Intelligence · Computer Science 2016-11-15 Ayan Acharya , Deepyaman Maiti , Aritra Banerjee , R. Janarthanan , Amit Konar

Optimal paths connecting randomly selected network nodes and fixed routers are studied analytically in the presence of non-linear overlap cost that penalizes congestion. Routing becomes increasingly more difficult as the number of selected…

Disordered Systems and Neural Networks · Physics 2012-05-15 Chi Ho Yeung , David Saad

Stochastic effects significantly influence the dynamics of traffic flows. Many dynamic traffic assignment (DTA) models attempt to capture these effects by prescribing a specific ratio that determines how flow splits across different routes…

Optimization and Control · Mathematics 2024-09-20 Lukas Graf , Tobias Harks , Michael Markl