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We investigate the influence of indirect connections, interregional distance and collective effects on the large-scale functional networks of the human cortex. We study topologies of empirically derived resting state networks (RSNs),…

Neurons and Cognition · Quantitative Biology 2013-02-18 Vesna Vuksanović , Philipp Hövel

Dynamic networks have been increasingly used to characterize brain connectivity that varies during resting and task states. In such characterizations, a connectivity network is typically measured at each time point for a subject over a…

Methodology · Statistics 2023-03-23 Maoyu Zhang , Biao Cai , Wenlin Dai , Dehan Kong , Hongyu Zhao , Jingfei Zhang

Intrinsic connectivity networks (ICNs) are specific dynamic functional brain networks that are consistently found under various conditions including rest and task. Studies have shown that some stimuli actually activate intrinsic…

Applications · Statistics 2021-07-21 Meini Tang , Chee-Ming Ting , Hernando Ombao

Background: Wide-field calcium imaging (WFCI) with genetically encoded calcium indicators allows for spatiotemporal recordings of neuronal activity in mice. When applied to the study of sleep, WFCI data are manually scored into the sleep…

Image and Video Processing · Electrical Eng. & Systems 2024-01-17 Xiaohui Zhang , Eric C. Landsness , Hanyang Miao , Wei Chen , Michelle Tang , Lindsey M. Brier , Joseph P. Culver , Jin-Moo Lee , Mark A. Anastasio

Early clinical assessment of Alzheimer's disease relies on behavior scores that measure a subject's language, memory, and cognitive skills. On the medical imaging side, functional magnetic resonance imaging has provided invaluable insights…

Signal Processing · Electrical Eng. & Systems 2026-04-14 Javier Salazar Cavazos , Maximillian Egan , Krisanne Litinas , Benjamin Hampstead , Scott Peltier

Background: Recent studies have indicated that functional connectivity is dynamic even during rest. A common approach to modeling the dynamic functional connectivity in whole-brain resting-state fMRI is to compute the correlation between…

Neurons and Cognition · Quantitative Biology 2019-11-05 Shih-Gu Huang , S. Balqis Samdin , Chee-Ming Ting , Hernando Ombao , Moo K. Chung

Global brain activity self-organizes into discrete patterns characterized by distinct behavioral observables and modes of information processing. The human thalamocortical system is a densely connected network where local neural activation…

Increased variability in performance has been associated with the emergence of several neurological and psychiatric pathologies. However, whether and how consistency of neuronal activity may also be indicative of an underlying pathology is…

Neurons and Cognition · Quantitative Biology 2014-10-31 J. H. Martínez , J. M. Pastor , P. Ariza , M. Zanin , D. Papo , F. Maestú , R. Bajo , S. Boccaletti , J. M. Buldú

Resting state functional connectivity estimates from MRI measures has become a promising tool to characterize human brain networks. There are, however, limitations in the method since several sources of errors have been seen to…

Neurons and Cognition · Quantitative Biology 2016-03-04 Pouya Ghaemmaghami

We study the statistical physics of a surprising phenomenon arising in large networks of excitable elements in response to noise: while at low noise, solutions remain in the vicinity of the resting state and large-noise solutions show…

Adaptation and Self-Organizing Systems · Physics 2020-04-01 Jonathan D. Touboul , Charlotte Piette , Laurent Venance , G. Bard Ermentrout

Historically, the analysis of stimulus-dependent time-frequency patterns has been the cornerstone of most electroencephalography (EEG) studies. The abnormal oscillations in high-frequency waves associated with psychotic disorders during…

Neurons and Cognition · Quantitative Biology 2023-01-05 Sadi Md. Redwan , Md Palash Uddin , Anwaar Ulhaq , Muhammad Imran Sharif

An increasingly important brain function analysis modality is functional connectivity analysis which regards connections as statistical codependency between the signals of different brain regions. Graph-based analysis of brain connectivity…

Signal Processing · Electrical Eng. & Systems 2024-01-08 Fengfan Zhao , Ercan Engin Kuruoglu

Brain age prediction based on neuroimaging data could help characterize both the typical brain development and neuropsychiatric disorders. Pattern recognition models built upon functional connectivity (FC) measures derived from resting…

Computer Vision and Pattern Recognition · Computer Science 2018-01-15 Hongming Li , Theodore D. Satterthwaite , Yong Fan

Symbolic methods of analysis are valuable tools for investigating complex time-dependent signals. In particular, the ordinal method defines sequences of symbols according to the ordering in which values appear in a time series. This method…

Data Analysis, Statistics and Probability · Physics 2018-10-17 C. Quintero-Quiroz , Luis Montesano , A. J. Pons , M. C. Torrent , J. García-Ojalvo , C. Masoller

Building comprehensive brain connectomes has proved of fundamental importance in resting-state fMRI (rs-fMRI) analysis. Based on the foundation of brain network, spatial-temporal-based graph convolutional networks have dramatically improved…

Machine Learning · Computer Science 2023-12-19 Rui Yang , Wenrui Dai , Huajun She , Yiping P. Du , Dapeng Wu , Hongkai Xiong

The human brain is a directional network system of brain regions involving directional connectivity. Seizures are a directional network phenomenon as abnormal neuronal activities start from a seizure onset zone (SOZ) and propagate to…

In this paper, we develop an approach to modeling high-dimensional networks with a large number of nodes arranged in a hierarchical and modular structure. We propose a novel multi-scale factor analysis (MSFA) model which partitions the…

Applications · Statistics 2020-04-10 Chee-Ming Ting , Hernando Ombao , Sh-Hussain Salleh

Network science has been extensively developed to characterize structural properties of complex systems, including brain networks inferred from neuroimaging data. As a result of the inference process, networks estimated from experimentally…

Neurons and Cognition · Quantitative Biology 2017-03-10 Catalina Obando , Fabrizio De Vico Fallani

Brain networks from functional MRI have advanced our understanding of cortical activity and its disruption in neurodegenerative disorders. Recent work has increasingly focused on dynamic (time-varying) brain networks that capture both…

Neurons and Cognition · Quantitative Biology 2026-04-14 Nicolas Rubido , Venia Batziou , Marwan Fuad , Vesna Vuksanovic

Creativity is a core cognitive capacity underlying innovation and adaptive problem solving, yet how it is represented in the brain's intrinsic functional architecture is not fully understood. While resting-state fMRI studies have identified…

Neurons and Cognition · Quantitative Biology 2026-01-21 Samir Damji , Simrut Kurry , Shazia'Ayn Babul , Joydeep Bhattacharya , Naznin Virji-Babul
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