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Learning across domains is challenging when data cannot be centralized due to privacy or heterogeneity, which limits the ability to train a single comprehensive model. Model merging provides an appealing alternative by consolidating…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-04-16 Junming Liu , Yusen Zhang , Rongchao Zhang , Wenkai Zhu , Tian Wu

An elastic rod model for semi-flexible polymers is presented. Theory for a continuum rod is reviewed, and it is shown that a popular discretised model used in numerical simulations gives the correct continuum limit. Correlation functions…

Biological Physics · Physics 2014-04-08 C. A. Brackley , A. N. Morozov , D. Marenduzzo

While Large Language Model (LLM) multi-agent systems (MAS) offer a transformative approach to simulating human behavior in complex systems, it remains largely unexplored whether these simulations can replicate realistic structural and…

Social and Information Networks · Computer Science 2026-05-14 Siqi Miao , Ziyang Chen , Yuhong Luo , Hans Hao-Hsun Hsu , Mufei Li , Kaiqing Zhang , Pan Li

MLMOD is a software package for incorporating machine learning approaches and models into simulations of microscale mechanics and molecular dynamics in LAMMPS. Recent machine learning approaches provide promising data-driven approaches for…

Machine Learning · Computer Science 2023-10-24 Paul J. Atzberger

Molecular Relational Learning (MRL) aims to understand interactions between molecular pairs, playing a critical role in advancing biochemical research. With the recent development of large language models (LLMs), a growing number of studies…

Machine Learning · Computer Science 2025-06-03 Zhuo Chen , Yizhen Zheng , Huan Yee Koh , Hongxin Xiang , Linjiang Chen , Wenjie Du , Yang Wang

We present a continuum model trained on molecular dynamics (MD) simulations for cellular membranes composed of an arbitrary number of lipid types. The model is constructed within the formalism of dynamic density functional theory and can be…

We propose Deep Residual Mixture Models (DRMMs), a novel deep generative model architecture. Compared to other deep models, DRMMs allow more flexible conditional sampling: The model can be trained once with all variables, and then used for…

Machine Learning · Computer Science 2021-07-22 Perttu Hämäläinen , Martin Trapp , Tuure Saloheimo , Arno Solin

Neural networks (NNs) are emerging as powerful tools to represent the dynamics of control systems with complicated physics or black-box components. Due to complexity of NNs, however, existing methods are unable to synthesize complex…

Systems and Control · Electrical Eng. & Systems 2022-03-22 Steven Adams , Morteza Lahijanian , Luca Laurenti

Large Action Models (LAMs) for AI Agents offer incredible potential but face challenges due to the need for high-quality training data, especially for multi-steps tasks that involve planning, executing tool calls, and responding to…

Warm dense matter systems created in the laboratory are highly dynamical. In such cases electron dynamics is often needed to accurately simulate the evolution and properties of the system. Large systems force one to make simple…

Quantum Gases · Physics 2014-08-13 Paul E. Grabowski

We study DNA self-assembly and DNA computation using a coarse-grained DNA model within the directional dynamic bonding framework {[}C. Svaneborg, Comp. Phys. Comm. 183, 1793 (2012){]}. In our model, a single nucleotide or domain is…

Soft Condensed Matter · Physics 2012-06-13 Carsten Svaneborg , Harold Fellermann , Steen Rasmussen

A fundamental objective of materials modeling is identifying atomic structures that align with experimental observables. Conventional approaches for disordered materials involve sampling from thermodynamic ensembles and hoping for an…

Materials Science · Physics 2025-09-30 Tigany Zarrouk , Miguel A. Caro

Molecular dynamics (MD) simulations are essential for understanding atomic-scale behaviors in materials science, yet writing LAMMPS scripts remains highly specialized and time-consuming tasks. Although LLMs show promise in code generation…

Computational Engineering, Finance, and Science · Computer Science 2026-02-09 Zhuofan Shi , Hubao A , Yufei Shao , Dongliang Huang , Hongxu An , Chunxiao Xin , Haiyang Shen , Zhenyu Wang , Yunshan Na , Gang Huang , Xiang Jing

Peridynamics (PD) is widely used to simulate structural failure. However, PD models are time-consuming. To improve the computational efficiency, we developed an adaptive coupling model between PD and classical continuum mechanics (PD-CCM)…

Computational Engineering, Finance, and Science · Computer Science 2024-10-24 JiuYi Li , ShanKun Liu , Fei Han , Yong Mei , YunHou Sun , FengJun Zhou

Large Atomistic Models (LAMs) have undergone remarkable progress recently, emerging as universal or fundamental representations of the potential energy surface defined by the first-principles calculations of atomistic systems. However, our…

Matched molecular pairs (MMPs) capture the local chemical edits that medicinal chemists routinely use to design analogs, but existing ML approaches either operate at the whole-molecule level with limited edit controllability or learn…

Machine Learning · Computer Science 2026-02-19 Bo Pan , Peter Zhiping Zhang , Hao-Wei Pang , Alex Zhu , Xiang Yu , Liying Zhang , Liang Zhao

DNA has the potential to realize a controllable liquid-liquid phase separation (LLPS) system, because the design of its base sequences results in programmable interactions. Here, we have developed a novel DNA-based LLPS system which enables…

Soft Condensed Matter · Physics 2019-07-25 Yusuke Sato , Tetsuro Sakamoto , Masahiro Takinoue

To fully understand, analyze, and determine the behavior of dynamical systems, it is crucial to identify their intrinsic modal coordinates. In nonlinear dynamical systems, this task is challenging as the modal transformation based on the…

Machine Learning · Computer Science 2025-03-13 Abdolvahhab Rostamijavanani , Shanwu Li , Yongchao Yang

Dynamic metasurface antennas (DMAs) are an emerging technology for next-generation wireless base stations, distinguished by hybrid analog/digital beamforming capabilities with low hardware complexity. However, the intrinsic coupling between…

Applied Physics · Physics 2025-07-11 Hugo Prod'homme , Philipp del Hougne

The mechanical model based on beads and springs, which we recently proposed to study non-specific DNA-protein interactions [J. Chem. Phys. 130, 015103 (2009)], was improved by describing proteins as sets of interconnected beads instead of…

Biological Physics · Physics 2009-10-29 Ana-Maria Florescu , Marc Joyeux