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In high dimensions, the classical Hotelling's $T^2$ test tends to have low power or becomes undefined due to singularity of the sample covariance matrix. In this paper, this problem is overcome by projecting the data matrix onto lower…

Methodology · Statistics 2014-05-09 Radhendushka Srivastava , Ping Li , David Ruppert

We propose a two-sample test for the means of high-dimensional data when the data dimension is much larger than the sample size. Hotelling's classical $T^2$ test does not work for this "large $p$, small $n$" situation. The proposed test…

Statistics Theory · Mathematics 2010-02-25 Song Xi Chen , Ying-Li Qin

We propose novel methodology for testing equality of model parameters between two high-dimensional populations. The technique is very general and applicable to a wide range of models. The method is based on sample splitting: the data is…

Methodology · Statistics 2013-01-17 Nicolas Städler , Sach Mukherjee

A common problem in genetics is that of testing whether a set of highly dependent gene expressions differ between two populations, typically in a high-dimensional setting where the data dimension is larger than the sample size. Most…

Methodology · Statistics 2015-03-11 Måns Thulin

We consider testing for two-sample means of high dimensional populations by thresholding. Two tests are investigated, which are designed for better power performance when the two population mean vectors differ only in sparsely populated…

Methodology · Statistics 2014-10-13 Song Xi Chen , Jun Li , Ping-Shou Zhong

Nonparametric two sample testing deals with the question of consistently deciding if two distributions are different, given samples from both, without making any parametric assumptions about the form of the distributions. The current…

Statistics Theory · Mathematics 2014-11-25 Aaditya Ramdas , Sashank J. Reddi , Barnabas Poczos , Aarti Singh , Larry Wasserman

We propose a two-sample test for detecting the difference between mean vectors in a high-dimensional regime based on a ridge-regularized Hotelling's $T^2$. To choose the regularization parameter, a method is derived that aims at maximizing…

Methodology · Statistics 2018-02-20 Haoran Li , Alexander Aue , Debashis Paul , Jie Peng , Pei Wang

Asymptotic methods for hypothesis testing in high-dimensional data usually require the dimension of the observations to increase to infinity, often with an additional relationship between the dimension (say, $p$) and the sample size (say,…

Methodology · Statistics 2025-12-11 Ritabrata Karmakar , Joydeep Chowdhury , Subhajit Dutta , Marc G. Genton

The classic likelihood ratio test for testing the equality of two covariance matrices breakdowns due to the singularity of the sample covariance matrices when the data dimension $p$ is larger than the sample size $n$. In this paper, we…

Methodology · Statistics 2015-11-06 Tung-Lung Wu , Ping Li

Statistical techniques are used in all branches of science to determine the feasibility of quantitative hypotheses. One of the most basic applications of statistical techniques in comparative analysis is the test of equality of two…

Methodology · Statistics 2018-05-01 Ayanendranath Basu , Abhijit Mandal , Nirian Martin , Leandro Pardo

Estimation and hypothesis tests for the covariance matrix in high dimensions is a challenging problem as the traditional multivariate asymptotic theory is no longer valid. When the dimension is larger than or increasing with the sample…

Methodology · Statistics 2020-11-18 Deepak Nag Ayyala , Santu Ghosh , Daniel F. Linder

Asymptotic methods for hypothesis testing in high-dimensional data usually require the dimension of the observations to increase to infinity, often with an additional condition on its rate of increase compared to the sample size. On the…

Statistics Theory · Mathematics 2024-03-26 Joydeep Chowdhury , Subhajit Dutta , Marc G. Genton

Testing differences in mean vectors is a fundamental task in the analysis of high-dimensional compositional data. Existing methods may suffer from low power if the underlying signal pattern is in a situation that does not favor the deployed…

Methodology · Statistics 2025-03-11 Danning Li , Lingzhou Xue , Haoyi Yang , Xiufan Yu

We consider multivariate two-sample tests of means, where the location shift between the two populations is expected to be related to a known graph structure. An important application of such tests is the detection of differentially…

Quantitative Methods · Quantitative Biology 2014-05-16 Laurent Jacob , Pierre Neuvial , Sandrine Dudoit

Hypothesis testing in high dimensional data is a notoriously difficult problem without direct access to competing models' likelihood functions. This paper argues that statistical divergences can be used to quantify the difference between…

Data Analysis, Statistics and Probability · Physics 2024-08-02 Jeremy J. H. Wilkinson , Christopher G. Lester

It has been a long history in testing whether a mean vector with a fixed dimension has a specified value. Some well-known tests include the Hotelling $T^2$-test and the empirical likelihood ratio test proposed by Owen [Biometrika 75 (1988)…

Methodology · Statistics 2014-05-21 Liang Peng , Yongcheng Qi , Fang Wang

High-dimensional data, where the dimension of the feature space is much larger than sample size, arise in a number of statistical applications. In this context, we construct the generalized multivariate sign transformation, defined as a…

Methodology · Statistics 2021-07-05 Subhabrata Majumdar , Snigdhansu Chatterjee

Power-enhanced tests with high-dimensional data have received growing attention in theoretical and applied statistics in recent years. Existing tests possess their respective high-power regions, and we may lack prior knowledge about the…

Methodology · Statistics 2021-10-01 Xiufan Yu , Danning Li , Lingzhou Xue , Runze Li

In this paper, we study the problem of testing the mean vectors of high dimensional data in both one-sample and two-sample cases. The proposed testing procedures employ maximum-type statistics and the parametric bootstrap techniques to…

Statistics Theory · Mathematics 2018-01-23 Jinyuan Chang , Chao Zheng , Wen-Xin Zhou , Wen Zhou

Motivated by the likelihood ratio test under the Gaussian assumption, we develop a maximum sum-of-squares test for conducting hypothesis testing on high dimensional mean vector. The proposed test which incorporates the dependence among the…

Methodology · Statistics 2015-10-21 Xianyang Zhang
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