English
Related papers

Related papers: Estimation of Parameters in DNA Mixture Analysis

200 papers

Variational methods for parameter estimation are an active research area, potentially offering computationally tractable heuristics with theoretical performance bounds. We build on recent work that applies such methods to network data, and…

Statistics Theory · Mathematics 2013-10-30 Peter Bickel , David Choi , Xiangyu Chang , Hai Zhang

Previous work on sensitivity analysis in Bayesian networks has focused on single parameters, where the goal is to understand the sensitivity of queries to single parameter changes, and to identify single parameter changes that would enforce…

Artificial Intelligence · Computer Science 2012-07-19 Hei Chan , Adnan Darwiche

We study Bayesian estimation of finite mixture models in a general setup where the number of components is unknown and allowed to grow with the sample size. An assumption on growing number of components is a natural one as the degree of…

Statistics Theory · Mathematics 2022-03-18 Ilsang Ohn , Lizhen Lin

Three-way data structures, characterized by three entities, the units, the variables and the occasions, are frequent in biological studies. In RNA sequencing, three-way data structures are obtained when high-throughput transcriptome…

Methodology · Statistics 2022-06-22 Anjali Silva , Steven J. Rothstein , Paul D. McNicholas , Xiaoke Qin , Sanjeena Subedi

In this paper, we present a novel approach to accelerate the Bayesian inference process, focusing specifically on the nested sampling algorithms. Bayesian inference plays a crucial role in cosmological parameter estimation, providing a…

Instrumentation and Methods for Astrophysics · Physics 2024-10-17 Isidro Gómez-Vargas , J. Alberto Vázquez

The correlated binomial (CB) distribution was proposed by Luce\~no (Computational Statistics $\&$ Data Analysis, 20, 1995, 511-520) as an alternative to the binomial distribution for the analysis of the data in the presence of correlations…

Methodology · Statistics 2022-02-25 Andrea Bennett , Min Wang

When presenting forensic evidence, such as a DNA match, experts often use the Likelihood ratio (LR) to explain the impact of evidence . The LR measures the probative value of the evidence with respect to a single hypothesis such as 'DNA…

Applications · Statistics 2021-06-11 Norman Fenton , Martin Neil

Birnbaum-Saunders models have been widely used to model positively skewed data. In this paper, we introduce a bivariate Birnbaum-Saunders distribution which has the means as parameters. We present some properties of the univariate and…

Methodology · Statistics 2018-05-01 Helton Saulo , Jeremias Leão , Roberto Vila , Victor Leiva , Vera Tomazella

In this paper, distributed Bayesian detection problems with unknown prior probabilities of hypotheses are considered. The sensors obtain observations which are conditionally dependent across sensors and their probability density functions…

Information Theory · Computer Science 2012-09-20 Xiaojing Shen , Pramod K. Varshney , Yunmin Zhu

Recent large scale genome wide association analysis involves large scale linear mixed models. Quantifying (co)-variance parameters in the mixed models with a restricted maximum likelihood method results in a score function which is the…

Numerical Analysis · Mathematics 2016-08-26 Shengxin Zhu

We derive uniform convergence rates for the maximum likelihood estimator and minimax lower bounds for parameter estimation in two-component location-scale Gaussian mixture models with unequal variances. We assume the mixing proportions of…

Statistics Theory · Mathematics 2020-06-02 Tudor Manole , Nhat Ho

We evaluate the uncertainty quality in neural networks using anomaly detection. We extract uncertainty measures (e.g. entropy) from the predictions of candidate models, use those measures as features for an anomaly detector, and gauge how…

Machine Learning · Statistics 2016-12-26 Ramon Oliveira , Pedro Tabacof , Eduardo Valle

Abstract In Extreme Value methodology the choice of threshold plays an important role in efficient modelling of observations exceeding the threshold. The threshold must be chosen high enough to ensure an unbiased extreme value index but…

Methodology · Statistics 2020-06-11 Andréhette Verster , Lizanne Raubenheimer

We introduce a novel class of Bayesian mixtures for normal linear regression models which incorporates a further Gaussian random component for the distribution of the predictor variables. The proposed cluster-weighted model aims to…

Methodology · Statistics 2026-05-26 Panagiotis Papastamoulis , Konstantinos Perrakis

Complex interactions between genes or proteins contribute a substantial part to phenotypic evolution. Here we develop an evolutionarily grounded method for the cross-species analysis of interaction networks by {\em alignment}, which maps…

Molecular Networks · Quantitative Biology 2009-11-13 Johannes Berg , Michael Lässig

This paper studies fundamental aspects of modelling data using multivariate Watson distributions. Although these distributions are natural for modelling axially symmetric data (i.e., unit vectors where $\pm \x$ are equivalent), for…

Computation · Statistics 2012-05-28 Suvrit Sra , Dmitrii Karp

Optimum parameter estimation methods require knowledge of a parametric probability density that statistically describes the available observations. In this work we examine Bayesian and non-Bayesian parameter estimation problems under a…

Applications · Statistics 2022-02-01 George V. Moustakides

A new maximum likelihood method for deconvoluting a continuous density with a positive lower bound on a known compact support in additive measurement error models with known error distribution using the approximate Bernstein type polynomial…

Methodology · Statistics 2018-01-30 Zhong Guan

Microarray data are often used to determine which genes are differentially expressed between groups, for example, between treatment and control groups. There are methods of determining which genes have a high probability of differential…

Quantitative Methods · Quantitative Biology 2007-05-23 David R. Bickel

Designing equivariance as an inductive bias into deep-nets has been a prominent approach to build effective models, e.g., a convolutional neural network incorporates translation equivariance. However, incorporating these inductive biases…

Machine Learning · Computer Science 2022-04-08 Raymond A. Yeh , Yuan-Ting Hu , Mark Hasegawa-Johnson , Alexander G. Schwing