Related papers: Automatic Network Reconstruction using ASP
Complex networks theory has commonly been used for modelling and understanding the interactions taking place between the elements composing complex systems. More recently, the use of generative models has gained momentum, as they allow…
As a programming paradigm, answer set programming (ASP) brings about the usual issue of the human error. Hence, it is desirable to provide automated techniques that could help the programmer to find the error. This paper addresses the…
Mathematical models are increasingly used in both academia and the pharmaceutical industry to understand how phenotypes emerge from systems of molecular interactions. However, their current construction as monolithic sets of equations…
Optimal control of complex environments with robotic systems faces two complementary and intertwined challenges: efficient organization of sensory state information and far-sighted action planning. Because the reinforcement learning…
Answer Set Programming (ASP) with stable model semantics has proven highly effective for knowledge representation and reasoning. However, the minimality requirement of stable models can be restrictive for applications requiring exploration…
A profound challenge for A-Life is to construct agents whose behavior is 'life-like' in a deep way. We propose an architecture and approach to constructing networks driving artificial agents, using processes analogous to the processes that…
Model-based diagnosis reasons backwards from a functional schematic of a system to isolate faults given observations of anomalous behavior. We develop a fully probabilistic approach to model based diagnosis and extend it to support…
Reconstruction of gene regulatory networks is the process of identifying gene dependency from gene expression profile through some computation techniques. In our human body, though all cells pose similar genetic material but the activation…
The inverse statistical problem of finding direct interactions in complex networks is difficult. In the natural sciences, well-controlled perturbation experiments are widely used to probe the structure of complex networks. However, our…
Biological systems are driven by intricate interactions among the complex array of molecules that comprise the cell. Many methods have been developed to reconstruct network models of those interactions. These methods often draw on large…
Rapid development in numerical modelling of materials and the complexity of new models increases quickly together with their computational demands. Despite the growing performance of modern computers and clusters, calibration of such models…
This paper proposes a novel approach to pattern classification using a probabilistic neural network model. The strategy is based on a compact-sized probabilistic neural network capable of continuous incremental learning and unlearning…
The AHP/ANP are multicriteria decision-making theories that deal with both hierarchic structures when the criteria are independent of the alternatives and with networks when there is any dependence within and between elements of the…
Direct cell reprogramming makes it feasible to reprogram abundant somatic cells into desired cells. It has great potential for regenerative medicine and tissue engineering. In this work, we study the control of biological networks, modelled…
Network models are applied across many domains where data can be represented as a network. Two prominent paradigms for modeling networks are statistical models (probabilistic models for the observed network) and mechanistic models (models…
Neural processes are a family of models which use neural networks to directly parametrise a map from data sets to predictions. Directly parametrising this map enables the use of expressive neural networks in small-data problems where neural…
Metabolic networks perform some of the most fundamental functions in living cells, including energy transduction and building block biosynthesis. While these are the best characterized networks in living systems, understanding their…
Self-adaptation solutions need to periodically monitor, reason about, and adapt a running system. The adaptation step involves generating an adaptation strategy and applying it to the running system whenever an anomaly arises. In this…
Approximate Bayesian Computation is widely used in systems biology for inferring parameters in stochastic gene regulatory network models. Its performance hinges critically on the ability to summarize high-dimensional system responses such…
Biological nervous systems consist of networks of diverse, sophisticated information processors in the form of neurons of different classes. In most artificial neural networks (ANNs), neural computation is abstracted to an activation…