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We examine the hydrodynamic performance of two cilia beating patterns reconstructed from experimental data. In their respective natural systems, the two beating patterns correspond to: (A) pumping-specialized cilia, and (B)…

Fluid Dynamics · Physics 2015-06-19 Hanliang Guo , Janna Nawroth , Yang Ding , Eva Kanso

A variety of swimming microorganisms, called ciliates, exploit the bending of a large number of small and densely-packed organelles, termed cilia, in order to propel themselves in a viscous fluid. We consider a spherical envelope model for…

Fluid Dynamics · Physics 2011-08-30 Sebastien Michelin , Eric Lauga

In a variety of biological processes, eukaryotic cells use cilia to transport flow. Although cilia have a remarkably conserved internal molecular structure, experimental observations report very diverse kinematics. To address this…

Biological Physics · Physics 2012-07-19 Christophe Eloy , Eric Lauga

Many biological microswimmers locomote by periodically beating the densely-packed cilia on their cell surface in a wave-like fashion. While the swimming mechanisms of ciliated microswimmers have been extensively studied both from the…

Soft Condensed Matter · Physics 2023-06-22 Hanliang Guo , Hai Zhu , Ruowen Liu , Marc Bonnet , Shravan Veerapaneni

On surfaces with many motile cilia, beats of the individual cilia coordinate to form metachronal waves. We present a theoretical framework that connects the dynamics of an individual cilium to the collective dynamics of a ciliary carpet via…

Soft Condensed Matter · Physics 2021-03-12 Fanlong Meng , Rachel R. Bennett , Nariya Uchida , Ramin Golestanian

Motile cilia are used by many eukaryotic cells to transport flow. Cilia-driven flows are important to many physiological functions, yet a deep understanding of the interplay between the mechanical structure of cilia and their physiological…

Fluid Dynamics · Physics 2016-04-06 Hanliang Guo , Eva Kanso

Large groups of active cilia collectively beat in a fluid medium as metachronal waves, essential for some microorganisms motility and for flow generation in mucociliary clearance. Several models can predict the emergence of metachronal…

Soft Condensed Matter · Physics 2024-05-08 Supravat Dey , Gladys Massiera , Estelle Pitard

Motile cilia beat in an asymmetric fashion in order to propel the surrounding fluid. When many cilia are located on a surface, their beating can synchronise such that their phases form metachronal waves. Here, we computationally study a…

Soft Condensed Matter · Physics 2023-09-29 David J. Hickey , Ramin Golestanian , Andrej Vilfan

Large arrays of active cilia coordinate their beat cycles into metachronal waves. These waves can travel in different directions with respect to the cilium's beat direction and the resulting direction of fluid propulsion. Hydrodynamic…

Biological Physics · Physics 2023-09-18 Rachel R. Bennett

Cells or bacteria carrying cilia on their surface show many striking features : alignment of cilia in an array, two-phase asymmetric beating for each cilium, coordination between cilia and existence of metachronal waves with a constant…

Biological Physics · Physics 2009-11-11 Boris Guirao , Jean-François Joanny

Microorganisms develop coordinated beating patterns on surfaces lined with cilia known as metachronal waves. For a chain of cilia attached to a flat ciliate, it has been shown that hydrodynamic interactions alone can lead the system to…

Fluid Dynamics · Physics 2016-03-23 Babak Nasouri , Gwynn J. Elfring

Ciliated tissues such as in the mammalian lungs, brains, and reproductive tracts, are specialized to pump fluid. They generate flows by the collective activity of hundreds of thousands of individual cilia that beat in a striking metachronal…

Soft Condensed Matter · Physics 2022-11-30 Anup Kanale , Feng Ling , Hanliang Guo , Sebastian Fuerthauer , Eva Kanso

Synchronization among arrays of beating cilia is one of the emergent phenomena in biological processes at meso-scopic scales. Strong inter-ciliary couplings modify the natural beating frequencies, $\omega$, of individual cilia to produce a…

Statistical Mechanics · Physics 2021-06-09 Hyunsuk Hong , Junghyo Jo , Changbong Hyeon , Hyunggyu Park

Motile cilia are a striking example of functional cellular organelle, conserved across all the eukaryotic species. Motile cilia allow swimming of cells and small organisms and transport of liquids across epithelial tissues. Whilst the…

Tissues and Organs · Quantitative Biology 2020-01-13 Pietro Cicuta

Cilia and flagella exhibit regular bending waves that perform mechanical work on the surrounding fluid, to propel cellular swimmers and pump fluids inside organisms. Here, we quantify a force-velocity relationship of the beating flagellum,…

Cell Behavior · Quantitative Biology 2016-12-21 Gary S. Klindt , Christian Ruloff , Christian Wanger , Benjamin M. Friedrich

Ciliated microorganisms near the base of the aquatic food chain either swim to encounter prey or attach at a substrate and generate feeding currents to capture passing particles. Here, we represent attached and swimming ciliates using a…

Fluid Dynamics · Physics 2024-04-23 Jingyi Liu , Yi Man , John H. Costello , Eva Kanso

In this work we study the effect of metachronal waves on the flow created by magnetically-driven plate-like artificial cilia in microchannels using numerical simulations. The simulations are performed using a coupled magneto-mechanical…

Fluid Dynamics · Physics 2015-05-30 Syed Khaderi , Jaap den Toonder , Patrick Onck

One of the vital functions of naturally occurring cilia is fluid transport. Biological cilia use spatially asymmetric strokes to generate a net fluid flow that can be utilized for feeding, swimming, and other functions. Biomimetic synthetic…

Fluid Dynamics · Physics 2018-07-19 Srinivas Hanasoge , Peter J. Hesketh , Alexander Alexeev

Microorganism motility often takes place within complex, viscoelastic fluid environments, e.g., sperm in cervicovaginal mucus and bacteria in biofilms. In such complex fluids, strains and stresses generated by the microorganism are stored…

Synchronisation is often observed in the swimming of flagellated cells, either for multiple appendages on the same organism or between the flagella of nearby cells. Beating cilia are also seen to synchronise their dynamics. In 1951, Taylor…

Biological Physics · Physics 2021-04-28 Weida Liao , Eric Lauga
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