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What are the molecular mechanisms that dictate protein-protein binding stability and whether those are related to the ones behind protein fold stability are still largely open questions. Indeed, despite many past efforts, we still lack…

Biological Physics · Physics 2023-11-28 Fausta Desantis , Mattia Miotto , Lorenzo Di Rienzo , Edoardo Milanetti , Giancarlo Ruocco

We consider the sedimentation of a colloidal gel under confinement in the direction of gravity. The confinement allows us to compare directly experiments and computer simulations, for the same system size in the vertical direction. The…

An important open question in the modeling of biological tissues is how to identify the right scale for coarse-graining, or equivalently, the right number of degrees of freedom. For confluent biological tissues, both vertex and Voronoi…

Tissues and Organs · Quantitative Biology 2023-06-08 Elizabeth Lawson-Keister , Tao Zhang , M. Lisa Manning

A coarse-grained computational model is used to investigate how the bending rigidity of a polymer under tension affects the formation of a trefoil knot. Thermodynamic integration techniques are applied to demonstrate that the free-energy…

Soft Condensed Matter · Physics 2012-11-13 Richard Matthews , Ard A. Louis , Christos N. Likos

Polydispersity is inevitable in industrially produced polymers. Established theories of polymer dynamics and rheology, however, were mostly built on monodisperse linear polymers. Dynamics of polydisperse polymers is yet to be fully explored…

Soft Condensed Matter · Physics 2021-06-29 Oluseye Adeyemi , Shiping Zhu , Li Xi

Both entangled and unentangled polymer melts exhibit stress overshoots when subject to shearing flow. The size of the overshoot depends on the applied shear rate and is related to relaxation mechanisms such as reptation, chain stretch and…

Soft Condensed Matter · Physics 2024-06-19 Marco Aurelio Galvani Cunha , Peter D. Olmsted , Mark O. Robbins

Physically assembled gels have promising applications in many fields because of their tunable mechanical properties. Here, we report the mechanical properties as a function of polymer volume fraction ($\phi$) for a physical gel system…

Soft Condensed Matter · Physics 2020-03-31 Satish Mishra , Rosa Maria Badani Prado , Santanu Kundu

We performed a series of molecular dynamics simulations on monodisperse polymer melts to investigate the formation of shear banding. Under high shear rates, shear banding occurs, which is accompanied with the entanglement heterogeneity…

Soft Condensed Matter · Physics 2023-09-19 Fan Peng , Renkuan Cao , Cui Nie , Tingyu Xu , Liangbin Li

Chain-like macromolecules in solution, whether biological or synthetic, transform from an extended conformation to a compact one when temperature or other system parameters change. This collapse transition is relevant in various phenomena,…

Soft Condensed Matter · Physics 2026-05-18 Yanyan Zhu , Haim Diamant , David Andelman

Synthetic copolymers and biopolymers, such as polypeptides and double-stranded DNA, often exhibit strong variations in bending stiffness along their contour, which can significantly impact conformational behavior at larger scales. To…

Soft Condensed Matter · Physics 2025-11-04 Yannick Witzky , Friederike Schmid , Arash Nikoubashman

The breakage of a polymer chain of segments, coupled by anharmonic bonds with applied constant external tensile force is studied by means of Molecular Dynamics simulation. We show that the mean life time of the chain becomes progressively…

Soft Condensed Matter · Physics 2015-05-27 J. Paturej , A. Milchev , V. G. Rostiashvili , T. A. Vilgis

Rigid, cage-like molecules, like diamondoids, show unique self-assembly behavior, such as templating 1-D nanomaterial assembly via pathways that are typically blocked for such bulky substituents. We investigate molecular forces between…

Materials Science · Physics 2020-10-30 Ella M. King , Matthew A. Gebbie , Nicholas A. Melosh

We investigate the relation between backbone and side-chain ordering in a small protein. For this purpos e we have performed multicanonical simulations of the villin headpiece subdomain HP-36, an often used to y model in protein studies.…

Biological Physics · Physics 2009-11-13 Y. Wei , W. Nadler , U. H. E. Hansmann

We study the structure and interfacial properties of model athermal mixtures of colloids and excluded volume polymers. The colloid particles are modeled as hard spheres whereas the polymer coils are modeled as chains formed from…

Soft Condensed Matter · Physics 2007-05-23 Pawel Bryk

We investigate the influence of static correlations beyond the pair level on the dynamics of selected model glass-formers. We compare the pair structure, angular distribution functions, and statistics of Voronoi polyhedra of two well-known…

Statistical Mechanics · Physics 2011-06-01 Daniele Coslovich

We examine the thermally-induced fracture of an unstrained polymer chain of discrete segments coupled by an anharmonic potential by means of Molecular Dynamics simulation with a Langevin thermostat. Cases of both under- and over-damped…

Soft Condensed Matter · Physics 2015-05-27 J. Paturej , A. Milchev , V. G. Rostiashvili , T. A. Vilgis

The peculiar linear temperature-dependent swelling of core-shell microgels has been conjectured to be linked to the core-shell architecture combining materials of different transition temperatures. Here the structure of pNIPMAM-core and…

Many composite materials, both natural and fabricated, process a Voronoi like architecture or microstructure. Furthermore, the stochasticity and connectivity of Voronoi tessellation endow the composite materials constructed by this kind of…

Materials Science · Physics 2022-09-01 Zhengyang Zhang , Hanxing Zhu , Ru Yuan , Sanmin Wang , Yanming Wang , Tongxiang Fan , Yacine Rezgui , Di Zhang

We study the effect of freeze-thaw cycling on the packing fraction of equal spheres immersed in water. The water located between the grains experiences a dilatation during freezing and a contraction during melting. After several cycles, the…

Disordered Systems and Neural Networks · Physics 2015-03-02 F. Ludewig , N. Vandewalle , S. Dorbolo , M. Pakpour , G. Lumay

Polymer melts undergoing large deformation by uniaxial elongation are studied by molecular dynamics simulations of bead-spring chains in melts. Applying a primitive path analysis to strongly deformed polymer melts, the role of topological…

Soft Condensed Matter · Physics 2019-09-11 Hsiao-Ping Hsu , Kurt Kremer