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We propose and investigate a delayed model that studies the relationship between HIV and the immune system during the natural course of infection and in the context of antiviral treatment regimes. Sufficient criteria for local asymptotic…

Optimization and Control · Mathematics 2018-03-19 Diana Rocha , Cristiana J. Silva , Delfim F. M. Torres

In this paper, we present a methodology for stability analysis of a general class of systems defined by coupled Partial Differential Equations (PDEs) with spatially dependent coefficients and a general class of boundary conditions. This…

Optimization and Control · Mathematics 2016-03-28 Evgeny Meyer , Matthew M. Peet

We study convergence properties of competing epidemic models of the Susceptible-Infected-Susceptible (SIS) type. The SIS epidemic model has seen widespread popularity in modelling the spreading dynamics of contagions such as viruses,…

Systems and Control · Electrical Eng. & Systems 2022-10-12 Vishwaraj Doshi , Shailaja Mallick , Do Young eun

The world is still fighting against COVID-19, which has been lasting for more than a year. Till date, it has been a greatest challenge to human beings in fighting against COVID-19 since, the pathogen SARS-COV-2 that causes COVID-19 has…

Populations and Evolution · Quantitative Biology 2021-06-17 P. Tamilalagan , B. Krithika , P. Manivannan

Mathematical models describing SARS-CoV-2 dynamics and the corresponding immune responses in patients with COVID-19 can be critical to evaluate possible clinical outcomes of antiviral treatments. In this work, based on the concept of virus…

Mathematical models for physiological processes aid qualitative understanding of the impact of various parameters on the underlying process. We analyse two such models for human physiological processes: the Mackey-Glass and the Lasota…

Systems and Control · Computer Science 2018-10-12 Sreelakshmi Manjunath , Gopal Krishna Kamath , Gaurav Raina

We present a nonlinear dynamical approximation method for time-dependent Partial Differential Equations (PDEs). The approach makes use of parametrized decoder functions, and provides a general, and principled way of understanding and…

Numerical Analysis · Mathematics 2025-05-20 Daan Bon , Benjamin Caris , Olga Mula

We study an epidemic model for a constant population by taking into account four compartments of the individuals characterizing their states of health. Each individual is in one of the compartments susceptible (S); incubated - infected yet…

Populations and Evolution · Quantitative Biology 2023-04-20 Teo Granger , Thomas M. Michelitsch , Michael Bestehorn , Alejandro P. Riascos , Bernard A. Collet

In [Math. Comput. Sci. 12 (2018), no. 2, 111--127], a delayed model describing the dynamics of the Human Immunodeficiency Virus (HIV) with Cytotoxic T Lymphocytes (CTL) immune response is investigated by Allali, Harroudi and Torres. Here,…

Dynamical Systems · Mathematics 2022-10-03 Sandra Vaz , Delfim F. M. Torres

Viral kinetics have been extensively studied in the past through the use of spatially well-mixed ordinary differential equations describing the time evolution of the diseased state. However, emerging spatial structures such as localized…

Cell Behavior · Quantitative Biology 2024-04-02 Catherine Beauchemin

Experiments have shown that hepatitis C virus (HCV) infections in vitro disseminate both distally via the release and diffusion of cell-free virus through the medium, and locally via direct, cell-to-cell transmission. To determine the…

Cell Behavior · Quantitative Biology 2021-02-11 Kenneth Blahut , Christian Quirouette , Jordan J. Feld , Shingo Iwami , Catherine A. A. Beauchemin

Using dynamic cluster quantum Monte Carlo simulations, we study the superconducting behavior of a 1/8 doped two-dimensional Hubbard model with imposed uni-directional stripe-like charge density wave modulation. We find a significant…

Superconductivity · Physics 2015-05-14 T. A. Maier , G. Alvarez , M. Summers , T. C. Schulthess

The classical theory of Kosambi-Cartan-Chern (KCC) developed in differential geometry provides a powerful method for analyzing the behaviors of dynamical systems. In the KCC theory, the properties of a dynamical system are described in…

Symbolic Computation · Computer Science 2024-06-18 Bo Huang , Dongming Wang , Jing Yang

In this paper we study a discrete-time SIS (susceptible-infected-susceptible) model, where the infection and healing parameters and the underlying network may change over time. We provide conditions for the model to be well-defined and…

Systems and Control · Electrical Eng. & Systems 2020-10-23 Philip E Pare , Sebin Gracy , Henrik Sandberg , Karl Henrik Johansson

Pattern formation analysis of eco-epidemiological models with cannibalism and disease has been less explored in the literature. Therefore, motivated by this, we have proposed a diffusive eco-epidemiological model and performed pattern…

Analysis of PDEs · Mathematics 2021-03-09 Nitu Kumari , Vikas Kumar , Ravi P. Agarwal

Subject-specific modeling is a powerful tool in cardiovascular research, providing insights beyond the reach of current clinical diagnostics. Limitations in available clinical data require the incorporation of uncertainty into models to…

Applications · Statistics 2025-07-16 Amirreza Kachabi , Sofia Altieri Correa , Naomi C. Chesler , Mitchel J. Colebank

This article conducts an in-depth investigation of a new spatio-temporal model for the cocaine-heroin epidemiological model with vital dynamics, incorporating the Laplacian operator. The study rigorously establishes the existence,…

Dynamical Systems · Mathematics 2025-05-13 Achraf Zinihi , Moulay Rchid Sidi Ammi , Matthias Ehrhardt , Ahmed Bachir

We study a disordered system of interacting bosons described by the Bose-Hubbard Hamiltonian with random tunneling amplitudes. We derive the condition for the stability of the replica-symmetric solution for this model. Following the scheme…

Disordered Systems and Neural Networks · Physics 2026-03-24 Anna M. Piekarska , Tadeusz K. Kopeć

Latin hypercube sampling (LHS) is generalized in terms of a spectrum of stratified sampling (SS) designs referred to as partially stratified sample (PSS) designs. True SS and LHS are shown to represent the extremes of the PSS spectrum. The…

Computation · Statistics 2015-12-14 Michael D. Shields , Jiaxin Zhang

In this paper, we propose a delayed cytokine-enhanced viral infection model incorporating saturation incidence and immune response. We compute the basic reproduction numbers and introduce a convex cone to discuss the impact of non-negative…

Dynamical Systems · Mathematics 2024-09-17 Xiaodong Cao , Songbo Hou , Xiaoqing Kong
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