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Energy functions for pure and heterogenous systems are one of the backbones for molecular simulation of condensed phase systems. With the advent of machine learned potential energy surfaces (ML-PESs) a new era has started. Statistical…

Bond graphs can be used to build thermodynamically-compliant hierarchical models of biomolecular systems. As bond graphs have been widely used to model, analyse and synthesise engineering systems, this paper suggests that they can play the…

Molecular Networks · Quantitative Biology 2016-06-06 Peter Gawthrop , Edmund Crampin

Modern buildings encompass complex dynamics of multiple electrical, mechanical, and control systems. One of the biggest hurdles in applying conventional model-based optimization and control methods to building energy management is the huge…

Optimization and Control · Mathematics 2017-11-08 Yize Chen , Yuanyuan Shi , Baosen Zhang

Control architectures and autonomy stacks for complex engineering systems are often divided into layers to decompose a complex problem and solution into distinct, manageable sub-problems. To simplify designs, uncertainties are often ignored…

Optimization and Control · Mathematics 2021-12-30 Tyler Summers , Maryam Kamgarpour

Model Driven Engineering (MDE) has been widely applied in software development, aiming to facilitate the coordination among various stakeholders. Such a methodology allows for a more efficient and effective development process.…

Software Engineering · Computer Science 2022-03-14 Juri Di Rocco , Davide Di Ruscio , Claudio Di Sipio , Phuong T. Nguyen , Alfonso Pierantonio

Subsurface simulations use computational models to predict the flow of fluids (e.g., oil, water, gas) through porous media. These simulations are pivotal in industrial applications such as petroleum production, where fast and accurate…

Machine Learning · Computer Science 2022-06-16 Tailin Wu , Qinchen Wang , Yinan Zhang , Rex Ying , Kaidi Cao , Rok Sosič , Ridwan Jalali , Hassan Hamam , Marko Maucec , Jure Leskovec

GROMACS is a widely used package for biomolecular simulation, and over the last two decades it has evolved from small-scale efficiency to advanced heterogeneous acceleration and multi-level parallelism targeting some of the largest…

Computational Engineering, Finance, and Science · Computer Science 2015-06-03 Páll Szilárd , Mark James Abraham , Carsten Kutzner , Berk Hess , Erik Lindahl

Monte Carlo simulations are an important tool in statistical physics, complex systems science, and many other fields. An increasing number of these simulations is run on parallel systems ranging from multicore desktop computers to…

Statistical Mechanics · Physics 2009-06-10 Stephan Mertens

We propose a framework for computing, optimizing and integrating with respect to a smooth marginal likelihood in statistical models that involve high-dimensional parameters/latent variables and continuous low-dimensional hyperparameters.…

Methodology · Statistics 2026-02-10 Omiros Papaspiliopoulos , Timothée Stumpf-Fétizon , Jonathan Weare

The cost of moving data between the memory units and the compute units is a major contributor to the execution time and energy consumption of modern workloads in computing systems. At the same time, we are witnessing an enormous amount of…

Hardware Architecture · Computer Science 2022-08-19 Gagandeep Singh

AliEn is a production environment that implements several components of the Grid paradigm needed to simulate, reconstruct and analyse HEP data in a distributed way. The system is built around Open Source components, uses the Web Services…

Distributed, Parallel, and Cluster Computing · Computer Science 2007-05-23 P. Buncic , P. Saiz , A. J. Peters

This paper presents our work on designing a parallel platform for large-scale reservoir simulations. Detailed components, such as grid and linear solver, and data structures are introduced, which can serve as a guide to parallel reservoir…

Computational Engineering, Finance, and Science · Computer Science 2018-09-05 Hui Liu , Kun Wang , Bo Yang , Zhangxin Chen

Interest in parallel architectures applied to real time selections is growing in High Energy Physics (HEP) experiments. In this paper we describe performance measurements of Graphic Processing Units (GPUs) and Intel Many Integrated Core…

Instrumentation and Detectors · Physics 2014-11-26 S. Amerio , D. Bastieri , M. Corvo , A. Gianelle , W. Ketchum , T. Liu , A. Lonardo , D. Lucchesi , S. Poprocki , R. Rivera , L. Tosoratto , P. Vicini , P. Wittich

This paper explores the multi-access distributed computing (MADC) model, a novel distributed computing framework where mapper and reducer nodes are distinct entities. Unlike traditional MapReduce frameworks, MADC leverages coding-theoretic…

Information Theory · Computer Science 2025-08-08 Shanuja Sasi , Onur Günlü

The Massive Parallel Computation (MPC) model is a theoretical framework for popular parallel and distributed platforms such as MapReduce, Hadoop, or Spark. We consider the task of computing a large matching or small vertex cover in this…

Data Structures and Algorithms · Computer Science 2018-07-24 Krzysztof Onak

The use of machine learning techniques has expanded in education research, driven by the rich data from digital learning environments and institutional data warehouses. However, replication of machine learned models in the domain of the…

Computers and Society · Computer Science 2018-08-23 Josh Gardner , Yuming Yang , Ryan Baker , Christopher Brooks

With the rapid advancement of Big Data platforms such as Hadoop, Spark, and Dataflow, many tools are being developed that are intended to provide end users with an interactive environment for large-scale data analysis (e.g., IQmulus).…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-10-25 Amit Kumar Mondal , Banani Roy , Chanchal K. Roy , Kevin A. Schneider

Processing-in-Memory (PIM) has emerged as a promising computing paradigm to address the memory wall and the fundamental bottleneck of the von Neumann architecture by reducing costly data movement between memory and processing units. As with…

Hardware Architecture · Computer Science 2025-12-02 Mahdi Aghaei , Saba Ebrahimi , Mohammad Saleh Arafati , Elham Cheshmikhani , Dara Rahmati , Saeid Gorgin , Jungrae Kim

Brute-force simulations for dynamics on very large networks are quite expensive. While phenomenological treatments may capture some macroscopic properties, they often ignore important microscopic details. Fortunately, one may be only…

Physics and Society · Physics 2016-05-17 Chuansheng Shen , Hanshuang Chen , Zhonghuai Hou , Jürgen Kurths

This paper introduces a novel, open-source MARL simulation framework for studying implicit cooperation in LEMs, modeled as a decentralized partially observable Markov decision process and implemented as a Gymnasium environment for MARL. Our…

Systems and Control · Electrical Eng. & Systems 2026-02-19 Nelson Salazar-Pena , Alejandra Tabares , Andres Gonzalez-Mancera