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Subgraph GNNs enhance message-passing GNNs expressivity by representing graphs as sets of subgraphs, demonstrating impressive performance across various tasks. However, their scalability is hindered by the need to process large numbers of…

Machine Learning · Computer Science 2025-06-02 Guy Bar-Shalom , Yam Eitan , Fabrizio Frasca , Haggai Maron

The motivation of this work is to define cohomology classes in the space of knots that are both easy to find and to evaluate, by reducing the problem to simple linear algebra. We achieve this goal by defining a combinatorial graded cochain…

Geometric Topology · Mathematics 2016-01-14 Arnaud Mortier

The problem of RNA secondary structure design (also called inverse folding) is the following: given a target secondary structure, one aims to create a sequence that folds into, or is compatible with, a given structure. In several practical…

Quantitative Methods · Quantitative Biology 2013-08-02 Yu Zhou , Yann Ponty , Stéphane Vialette , Jérôme Waldispühl , Yi Zhang , Alain Denise

We extend our work for compression of currents and varifolds to a compression algorithm for the embedded normal cycles representation of shape, restricted to the constant normal kernel case, using the Nystrom approximation in Reproducing…

Numerical Analysis · Mathematics 2026-05-26 Allen Paul , Neill Campbell , Tony Shardlow

Representation learning on graphs has emerged as a powerful mechanism to automate feature vector generation for downstream machine learning tasks. The advances in representation on graphs have centered on both homogeneous and heterogeneous…

Machine Learning · Statistics 2020-11-23 Piotr Bielak , Kamil Tagowski , Maciej Falkiewicz , Tomasz Kajdanowicz , Nitesh V. Chawla

We introduce a quantum dynamic programming framework that allows us to directly extend to the quantum realm a large body of classical dynamic programming algorithms. The corresponding quantum dynamic programming algorithms retain the same…

We present a new, nucleotide-level model for RNA, oxRNA, based on the coarse-graining methodology recently developed for the oxDNA model of DNA. The model is designed to reproduce structural, mechanical and thermodynamic properties of RNA,…

Biological Physics · Physics 2014-06-18 Petr Šulc , Flavio Romano , Thomas E. Ouldridge , Jonathan P. K. Doye , Ard A. Louis

Many models have been proposed for vision and language tasks, especially the image-text retrieval task. All state-of-the-art (SOTA) models in this challenge contained hundreds of millions of parameters. They also were pretrained on a large…

Computer Vision and Pattern Recognition · Computer Science 2023-01-13 Manh-Duy Nguyen , Binh T. Nguyen , Cathal Gurrin

We study dynamic graph algorithms in the Massively Parallel Computation model, which was inspired by practical data processing systems. Our goal is to provide algorithms that can efficiently handle large batches of edge insertions and…

Data Structures and Algorithms · Computer Science 2021-01-12 Krzysztof Nowicki , Krzysztof Onak

The integration of Spiking Neural Networks (SNNs) and Graph Neural Networks (GNNs) is gradually attracting attention due to the low power consumption and high efficiency in processing the non-Euclidean data represented by graphs. However,…

Neural and Evolutionary Computing · Computer Science 2025-07-15 Nan Yin , Mengzhu Wang , Zhenghan Chen , Giulia De Masi , Bin Gu , Huan Xiong

A useful approach to the mathematical analysis of large-scale biological networks is based upon their decompositions into monotone dynamical systems. This paper deals with two computational problems associated to finding decompositions…

Molecular Networks · Quantitative Biology 2007-05-23 Bhaskar DasGupta , German Andres Enciso , Eduardo Sontag , Yi Zhang

Many complex systems involve interactions between more than two agents. Hypergraphs capture these higher-order interactions through hyperedges that may link more than two nodes. We consider the problem of embedding a hypergraph into…

Social and Information Networks · Computer Science 2023-01-06 Xue Gong , Desmond J. Higham , Konstantinos Zygalakis

We formulate the RNA folding problem as an $N\times N$ matrix field theory. This matrix formalism allows us to give a systematic classification of the terms in the partition function according to their topological character. The theory is…

Statistical Mechanics · Physics 2009-11-07 H. Orland , A. Zee

Graphs are a fundamental representation of complex, nonlinear structured data across various domains, including social networks and quantum systems. Quantum Graph Recurrent Neural Networks (QGRNNs) have been proposed to model quantum…

Quantum Physics · Physics 2025-07-01 Jawaher Kaldari , Saif Al-Kuwari

Recent advances in protein function prediction exploit graph-based deep learning approaches to correlate the structural and topological features of proteins with their molecular functions. However, proteins in vivo are not static but…

Biomolecules · Quantitative Biology 2022-11-22 Yuan Chiang , Wei-Han Hui , Shu-Wei Chang

The task of RNA design given a target structure aims to find a sequence that can fold into that structure. It is a computationally hard problem where some version(s) have been proven to be NP-hard. As a result, heuristic methods such as…

Biomolecules · Quantitative Biology 2024-12-13 Wei Yu Tang , Ning Dai , Tianshuo Zhou , David H. Mathews , Liang Huang

A lattice model of RNA denaturation which fully accounts for the excluded volume effects among nucleotides is proposed. A numerical study shows that interactions forming pseudoknots must be included in order to get a sharp continuous…

Soft Condensed Matter · Physics 2007-05-23 M. Baiesi , E. Orlandini , A. L. Stella

For a required payload, the existing reversible data hiding (RDH) methods always expect to reduce the embedding distortion as much as possible, such as by utilizing a well-designed predictor, taking into account the carrier-content…

Multimedia · Computer Science 2021-10-08 Hanzhou Wu

A hypergraph spectral sparsifier of a hypergraph $G$ is a weighted subgraph $H$ that approximates the Laplacian of $G$ to a specified precision. Recent work has shown that similar to ordinary graphs, there exist $\widetilde{O}(n)$-size…

Data Structures and Algorithms · Computer Science 2025-02-07 Sanjeev Khanna , Huan Li , Aaron Putterman

Deep generative models for graphs have exhibited promising performance in ever-increasing domains such as design of molecules (i.e, graph of atoms) and structure prediction of proteins (i.e., graph of amino acids). Existing work typically…

Machine Learning · Computer Science 2021-01-21 Wenbin Zhang , Liming Zhang , Dieter Pfoser , Liang Zhao
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