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Phase variation, or stochastic switching between alternative states of gene expression, is common among microbes, and may be important in coping with changing environments. We use a theoretical model to assess whether such switching is a…

Populations and Evolution · Quantitative Biology 2010-04-13 Paolo Visco , Rosalind J. Allen , Satya N. Majumdar , Martin R. Evans

The miniaturization of gears towards the nanoscale is a formidable task posing a variety of challenges to current fabrication technologies. In context, the understanding, via computer simulations, of the mechanisms mediating the transfer of…

Mesoscale and Nanoscale Physics · Physics 2020-09-25 Huang-Hsiang Lin , Jonathan Heinze , Alexander Croy , Rafael Gutierrez , Gianaurelio Cuniberti

Magnetotactic bacteria moving on circular orbits form hydrodynamically bound states. When close to a surface and with the tilting of the field in a direction close to the perpendicular to this surface these swarms move perpendicularly to…

Soft Condensed Matter · Physics 2017-07-11 K. Bente , G. Kitenbergs , D. Kriman , K. Erglis , M. Belovs , D. Faivre , A. Cebers

The rotor-router model is a deterministic process analogous to a simple random walk on a graph. This paper is concerned with a generalized model, functional-router model, which imitates a Markov chain possibly containing irrational…

Discrete Mathematics · Computer Science 2015-08-12 Takeharu Shiraga , Yukiko Yamauchi , Shuji Kijima , Masafumi Yamashita

Evolution has provided many organisms with sophisticated sensory systems that enable them to respond to signals in their environment. The response frequently involves alteration in the pattern of movement, such as the chemokinesis of the…

Molecular Networks · Quantitative Biology 2009-11-10 Reka Albert , Yu-wen Chiu , Hans G. Othmer

Mechanical cues like the rigidity of the substrate are main determinants for the decision making of adherent cells. Here we use a mechano-chemical model to predict the cellular response to varying substrate stiffness. The model equations…

Cell Behavior · Quantitative Biology 2010-07-08 A. Besser , U. S. Schwarz

During the past century, biologists and mathematicians investigated two mechanisms underlying bacteria motion: the run phase during which bacteria move in straight lines and the tumble phase in which they change their orientation. When…

Analysis of PDEs · Mathematics 2025-05-19 Alain Blaustein

Resistive switching is one of the foremost candidates for building novel types of non-volatile random access memories. Any practical implementation of such a memory cell calls for a strong miniaturization, at which point fluctuations start…

Materials Science · Physics 2017-10-11 Paul K. Radtke , Andrew L. Hazel , Arthur V. Straube , Lutz Schimansky-Geier

Motivated by observations of the dynamics of {\it Myxococcus xanthus}, we present a self-interacting random walk model that describes the competition between chemokinesis and chemotaxis. Cells are constrained to move in one dimension, but…

Statistical Mechanics · Physics 2016-08-31 Maria R. D'Orsogna , Marc Suchard , Tom Chou

Adhesive cell-substrate interactions are crucial for cell motility and are responsible for the necessary traction that propels cells. These interactions can also change the shape of the cell, analogous to liquid droplet wetting on adhesive…

The reaction-diffusion models have been extensively applied to explain the mechanism of pattern formations in early embryogenesis based on geometrically confined microtissues consisting of human pluripotent stem cells. Recently, mechanical…

Biological Physics · Physics 2022-11-22 Tiankai Zhao , Hongyan Yuan

In many biological systems, the movement of individual agents is commonly characterized as having multiple qualitatively distinct behaviors that arise from various biophysical states. This is true for vesicles in intracellular transport,…

Subcellular Processes · Quantitative Biology 2022-07-25 Maria-Veronica Ciocanel , John Fricks , Peter R. Kramer , Scott A. McKinley

From intracellular protein trafficking to large scale motion of animal groups, the physical concepts driving the self-organization of living systems are still largely unraveled. Selforganization of active entities, leading to novel phases…

Soft Condensed Matter · Physics 2019-11-12 Benoit Vincenti , Gabriel Ramos , Maria Luisa Cordero , Carine Douarche , Rodrigo Soto , Eric Clément

We propose a simple mathematical model that describes the time evolution of a self-propelled object on a liquid surface using such variables as the object location, the surface concentration of active molecules and the hydrodynamic surface…

Adaptation and Self-Organizing Systems · Physics 2020-02-05 Yuki Koyano , Hiroyuki Kitahata , Satoshi Nakata , Jerzy Gorecki

The stochastic driving force exerted by a single molecular motor (e.g., a kinesin, or myosin) moving on a periodic molecular track (microtubule, actin filament, etc.) is discussed from a general viewpoint open to experimental test. An…

Statistical Mechanics · Physics 2009-10-31 Michael E. Fisher , Anatoly B. Kolomeisky

Direct torque control is considered as one of the most efficient techniques for speed and/or position tracking control of induction motor drives. However, this control scheme has several drawbacks: the switching frequency may exceed the…

Systems and Control · Computer Science 2012-09-07 Jean Thomas , Anders Hansson

Transitions between solid-like and fluid-like states in living tissues have been found in steps of embryonic development and in stages of disease progression. Our current understanding of these transitions has been guided by experimental…

Soft Condensed Matter · Physics 2024-11-20 Steven J. Chisolm , Emily Guo , Vignesh Subramaniam , Kyle D. Schulze , Thomas E. Angelini

We investigate the dependence of switching current density on the junction sizes in the spin transfer torque nanopillar structures by using micromagnetic simulations. While the macro spin model predicts weak dependence of switching current…

Materials Science · Physics 2015-06-12 Chun-Yeol You , Myung-Hwa Jung

Cells use genetic switches to shift between alternate gene expression states, e.g., to adapt to new environments or to follow a developmental pathway. Here, we study the dynamics of switching in a generic-feedback on/off switch. Unlike…

Molecular Networks · Quantitative Biology 2015-05-27 Michael Assaf , Elijah Roberts , Zaida Luthey-Schulten

Motility is characteristic of life, but a common basis for movement has remained to be identified. Diverse systems in motion shift between two states depending on interactions that turnover at the rate of an applied cycle of force. Although…

Subcellular Processes · Quantitative Biology 2015-11-03 Henry G. Zot , Javier E. Hasbun , Nguyen Van Minh