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The bacterial flagellar motor drives the rotation of flagellar filaments and enables many species of bacteria to swim. Torque is generated by interaction of stator units, anchored to the peptidoglycan cell wall, with the rotor. Recent…

Subcellular Processes · Quantitative Biology 2010-08-18 G. Meacci , Y. Tu

Many swimming bacteria are propelled by flagellar motors that stochastically switch between the clockwise and counterclockwise rotation direction. While the switching dynamics are one of the most important characteristics of flagellar…

Subcellular Processes · Quantitative Biology 2008-11-18 Siebe B. van Albada , Sorin Tanase-Nicola , Pieter Rein ten Wolde

The bacterial flagellar motor (BFM) is responsible for driving bacterial locomotion and chemotaxis, fundamental processes in pathogenesis and biofilm formation. In the BFM, torque is generated at the interface between transmembrane proteins…

Biological Physics · Physics 2016-02-17 Kranthi K. Mandadapu , Jasmine A. Nirody , Richard M. Berry , George Oster

Rotation of a single bacterial flagellar motor is powered by multiple stators tethered to the cell wall. In a "power-stroke" model the observed independence of the speed at low load on the number of stators is explained by a…

Subcellular Processes · Quantitative Biology 2010-08-16 Giovanni Meacci , Ganhui Lan , Yuhai Tu

The bacterial flagellar motor is an ion-powered transmembrane protein complex which drives swimming in many bacterial species. The motor consists of a cytoplasmic 'rotor' ring and a number of 'stator' units, which are bound to the cell wall…

Biological Physics · Physics 2020-06-17 Jasmine A Nirody , Ashley L. Nord , Richard M. Berry

Recent experiments on the bacterial flagellar motor have shown that the structure of this nanomachine, which drives locomotion in a wide range of bacterial species, is more dynamic than previously believed. Specifically, the number of…

Biological Physics · Physics 2016-08-24 Jasmine A. Nirody , Richard M. Berry , George Oster

In this supporting information we briefly describe the torque-speed measurement procedure. We show the hook spring compliance used in the simulations. We analyze the distribution functions of the moving and waiting time intervals. We study…

Subcellular Processes · Quantitative Biology 2010-08-18 G. Meacci , Y. Tu

In this article, we develop a mathematical model for the rotary bacterial flagellar motor (BFM) based on the recently discovered structure of the stator complex (MotA$_5$MotB$_2$). The structure suggested that the stator also rotates. The…

Soft Condensed Matter · Physics 2022-02-15 Yuansheng Cao , Tairan Li , Yuhai Tu

A tiny bacterial flagellar motor rotates in both counter-clockwise (CCW) and clockwise (CW) rotational directions. The most important measurable characteristic of the flagellar motor is its torque versus angular speed relationship in CCW or…

Biological Physics · Physics 2021-09-07 Biswajit Das , Hao Ge

Flagellar motors enable bacteria to navigate their environments by switching rotation direction in response to external cues with high sensitivity. Previous work suggested that ultrasensitivity of the flagellar motor originates from…

Biological Physics · Physics 2025-02-06 Henry H. Mattingly , Yuhai Tu

The bacterial flagellar motor is a highly efficient rotary machine used by many bacteria to propel themselves. It has recently been shown that at low speeds its rotation proceeds in steps [Sowa et al. (2005) Nature 437, 916--919]. Here we…

Biological Physics · Physics 2009-10-25 Thierry Mora , Howard Yu , Yoshiyuki Sowa , Ned S. Wingreen

The bacterial flagellar motor (BFM) converts transmembrane ion flux into directed mechanical rotation, driving bacterial motility. Despite extensive study, the frictional forces and energetics governing its torque generation remain poorly…

Biological Physics · Physics 2025-12-18 N. J. Lopez-Alamilla , A. L. Nord , F. Pedaci , J. Palmeri , N. -O. Walliser

Bacterial flagellar motor is one of the most complex and sophisticated nano machineries in nature. A duty ratio $D$ is a fraction of time that the stator and the rotor interact and is a fundamental property to characterize the motor but…

Biological Physics · Physics 2019-06-26 Kento Sato , Shuichi Nakamura , Seishi Kudo , Shoichi Toyabe

In this Supporting information we provide background information on our model of the bacterial flagellar motor. We also derive the analytical solution of our coarse-grained model of the switching dynamics and explain the hybrid stochastic…

Subcellular Processes · Quantitative Biology 2008-11-20 Siebe B. van Albada , Sorin Tanase-Nicola , Pieter Rein ten Wolde

Many types of bacteria swim by rotating a bundle of helical filaments also called flagella. Each filament is driven by a rotary motor and a very flexible hook transmits the motor torque to the filament. We model it by discretizing…

Biological Physics · Physics 2012-01-04 Reinhard Vogel , Holger Stark

Unraveling bacterial strategies for spatial exploration is crucial for understanding the complexity in the organization of life. Bacterial motility determines the spatio-temporal structure of microbial communities, controls infection…

We present a minimal physical model for the flagellar motor that enables bacteria to swim. Our model explains the experimentally measured torque-speed relationship of the proton-driven E. coli motor at various pH and temperature conditions.…

Subcellular Processes · Quantitative Biology 2009-12-11 Thierry Mora , Howard Yu , Ned S. Wingreen

We study the chemotaxis of a population of genetically identical swimming bacteria undergoing run and tumble dynamics driven by stochastic switching between clockwise and counterclockwise rotation of the flagellar rotary system.…

Cell Behavior · Quantitative Biology 2020-07-17 Margaritis Voliotis , Jerko Rosko , Teuta Pilizota , Tanniemola Liverpool

The rotary motor of bacteria is a natural nano-technological marvel that enables cell locomotion by powering the rotation of semi-rigid helical flagellar filaments in fluid environments. It is well known that the motor operates essentially…

Biological Physics · Physics 2018-10-23 Debasish Das , Eric Lauga

Recent advances in microscopy techniques has uncovered unique aspects of flagella-driven motility in bacteria. A remarkable example is the discovery of flagellar wrapping, a phenomenon whereby a bacterium wraps its flagellum (or flagellar…

Soft Condensed Matter · Physics 2025-04-22 Takuro Kataoka , Taiju Yoneda , Daisuke Nakane , Hirofumi Wada
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