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A highly-efficient method for optical detection and separation of left- and right-handed chiral molecules is presented. The method utilizes a closed-loop three-state system in which the population dynamics depends on the phases of the three…

Quantum Physics · Physics 2019-05-08 Nikolay V. Vitanov , Michael Drewsen

Particular advantages of chiral molecules for direct detection of the time-dependence of pseudoscalar and the timelike-component of pseudovector cosmic fields are highlighted. Such fields are invoked in different models for cold dark matter…

High Energy Physics - Phenomenology · Physics 2020-09-23 Konstantin Gaul , Mikhail G. Kozlov , Timur A. Isaev , Robert Berger

Chiral spectroscopy is a powerful technique that enables to identify the chirality of matter through optical means. So far, experiments to check the chirality of matter or nanostructures have been carried out using free-space propagating…

Optics · Physics 2019-11-26 J. Enrique Vázquez-Lozano , Alejandro Martínez

Enantiodetection of chiral molecules is important to pharmaceutical drug production, chemical reaction control, and biological function designs. Traditional optical methods of enantiodetection rely on the weak magnetic-dipole or…

Chemical Physics · Physics 2022-09-14 Mao-Rui Cai , Chong Ye , Hui Dong , Yong Li

A novel optical method for distinguishing chiral molecules is proposed and validated within a quantum simulator employing a trapped-ion qudit. This approach correlates the sign disparity of the dipole moment of chiral molecules with…

Quantum Physics · Physics 2024-03-11 Teng Liu , Fa Zhao , Pengfei Lu , Qifeng Lao , Min Ding , Ji Bian , Feng Zhu , Le Luo

We perform experimental quantum polarimetry using a heralded single photon to analyze the optical activity of linearly polarized light traversing a chiral medium. Three kinds of estimators are considered to estimate the concentrations of…

Quantum Physics · Physics 2020-06-17 Seung-Jin Yoon , Joong-Sung Lee , Carsten Rockstuhl , Changhyoup Lee , Kwang-Geol Lee

Chirality is ubiquitous in nature and of fundamental importance in science. The present work focuses on understanding the conditions required to modify the chirality during ultrafast electronic motion by bringing enantiomers…

Chemical Physics · Physics 2021-01-04 Sucharita Giri , Alexandra Maxi Dudzinski , Jean Christophe Tremblay , Gopal Dixit

We introduce chiral rotational spectroscopy: a new technique that enables the determination of the orientated optical activity pseudotensor components $B_{XX}$, $B_{YY}$ and $B_{ZZ}$ of chiral molecules, in a manner that reveals the…

Atomic and Molecular Clusters · Physics 2018-01-16 Robert P. Cameron , Jörg B. Götte , Stephen M. Barnett

This work presents a quantum-limited optomechanical sensing platform for real-time detection and discrimination of chiral molecules, based on a multilayer hybrid plasmonic-mechanical resonator. Leveraging quantum zero-point motion and…

Optics · Physics 2025-07-29 Giuseppina Simone

This paper develops, in precise quantum electrodynamic terms, photonic attributes of the "optical chirality density", one of several measures long known to be conserved quantities for a vacuum electromagnetic field. The analysis lends…

Optics · Physics 2012-06-21 Matt M. Coles , David L. Andrews

The development of quantitative methods for characterizing molecular chirality can provide an important tool for studying chirality induced phenomena in molecular systems. Significant progress has been made in recent years toward…

Chemical Physics · Physics 2025-03-06 Jichen Feng , Ethan Abraham , Joseph Subotnik , Abraham Nitzan

Determination of optical absorption cross-section is always among the central importance of understanding a material. However its realization on individual nanostructures, such as carbon nanotubes, is experimentally challenging due to the…

Characterizing chirality is highly important for applications in the pharmaceutical industry, as well as in the study of dynamical chemical and biological systems. However, this task has remained challenging, especially due to the ongoing…

Chemical Physics · Physics 2022-01-28 Ofer Neufeld , Omri Wengrowicz , Or Peleg , Angel Rubio , Oren Cohen

Electronic circular dichroism (ECD) spectroscopy captures the chiroptical response of molecules, enabling absolute configuration assignment that is vital for enantioselective synthesis and drug design. The practical use of ECD spectra in…

Quantum Physics · Physics 2026-02-04 Amandeep Singh Bhatia , Sabre Kais

Determination of enantiomeric excess is important and remains challenges. We theoretically propose a new spectroscopic method for this issue based on the chirality-dependent AC Stark effects in cyclic three-level models under the…

Optics · Physics 2019-09-17 Chong Ye , Quansheng Zhang , Yu-Yuan Chen , Yong Li

The practical applications of chiral discrimination are usually limited by the weak chiral response of enantiomers and the high complexity of detection methods. Here, we propose to use the C lines (i.e., lines of polarization singularities)…

Optics · Physics 2022-03-22 Shiqi Jia , Jie Peng , Yuqiong Cheng , Shubo Wang

Molecular chirality is conventionally understood as space-inversion-symmetry breaking in the equilibrium structure of molecules. Less well known is that achiral molecules can be made chiral through extreme rotational excitation. Here, we…

Chemical Physics · Physics 2018-11-14 Alec Owens , Andrey Yachmenev , Sergei N. Yurchenko , Jochen Küpper

Metasurfaces, the two-dimensional analogues of metamaterials, are ideal platforms for sensing molecular chirality at the nanoscale, e.g. of inclusions of natural optically active molecules, as they offer large accessible areas (they are…

Applied Physics · Physics 2020-08-19 Sotiris Droulias

Chirality, a pervasive phenomenon in nature, is widely studied across diverse fields including the origins of life, chemical catalysis, drug discovery, and physical optoelectronics. The investigations of natural chiral materials have been…

Mesoscale and Nanoscale Physics · Physics 2025-02-27 Xiu Zhang , Lu Zhang , Junzhi Zhu , Tingxiao Qin , Haiyun Huang , Baixu Xiang , Haiyun Liu , Qihua Xiong

A new scheme for enantiomer differentiation of chiral molecules using a pair of linearly polarized intense ultrashort laser pulses with skewed mutual polarization is presented. The technique relies on the fact that the off-diagonal…

Chemical Physics · Physics 2017-05-04 Andrey Yachmenev , Sergei N. Yurchenko