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When a system deviates from equilibrium, it is possible to manipulate and control it to drive it towards equilibrium within a finite time $t_f$, even reducing its natural relaxation time scale $\tau_{relax}$. Although numerous theoretical…

Statistical Mechanics · Physics 2024-02-26 Diego Rengifo , Gabriel Téllez

Molecular dynamics is a powerful tool for studying the thermodynamics and kinetics of complex molecular events. However, these simulations can rarely sample the required time scales in practice. Transition path sampling overcomes this…

Chemical Physics · Physics 2023-07-31 Gianmarco Lazzeri , Hendrik Jung , Peter G. Bolhuis , Roberto Covino

Parallel applications often rely on work stealing schedulers in combination with fine-grained tasking to achieve high performance and scalability. However, reducing the total energy consumption in the context of work stealing runtimes is…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-01-31 Jing Chen , Madhavan Manivannan , Mustafa Abduljabbar , Miquel Pericàs

The pseudopotential and free energy models are two popular extensions of the lattice Boltzmann method for multiphase flows. Until now, they have been developed apart from each other in the literature. However, important questions about…

In this paper, we present a study on how to develop an efficient multiscale simulation strategy for the dynamics of chemically active systems on low-dimensional supports. Such reactions are encountered in a wide variety of situations,…

Computational Physics · Physics 2015-06-04 Giacomo Mazzi , Yannick De Decker , Giovanni Samaey

The present paper proposes an adaptive biasing potential for the computation of free energy landscapes. It is motivated by statistical learning arguments and unifies the tasks of biasing the molecular dynamics to escape free energy wells…

Mathematical Physics · Physics 2018-03-05 I. Bilionis , P. S. Koutsourelakis

To directly simulate rare events using atomistic molecular dynamics is a significant challenge in computational biophysics. Well-established enhanced-sampling techniques do exist to obtain the thermodynamic functions for such systems. But…

Statistical Mechanics · Physics 2020-07-21 Dhiman Ray , Ioan Andricioaei

Ensuring a satisfactory statistical convergence of anharmonic thermodynamic properties requires sampling of many atomic configurations, however the methods to obtain those necessarily produce correlated samples, thereby reducing the…

Statistical Mechanics · Physics 2022-06-07 Erki Metsanurk

We derive the optimal estimates of the free energies of an arbitrary number of thermodynamic states from nonequilibrium work measurements; the work data are collected from forward and reverse switching processes and obey a fluctuation…

Statistical Mechanics · Physics 2009-11-11 Paul Maragakis , Martin Spichty , Martin Karplus

Confidence estimation infers a probability for whether each model output is correct or not. While predicting such binary correctness is sensible for tasks with exact answers, free-form generation tasks are often more nuanced, with output…

Computation and Language · Computer Science 2026-01-14 Chi-Yang Hsu , Alexander Braylan , Yiheng Su , Matthew Lease , Omar Alonso

An electrostatic gyrokinetic-based model is applied to simulate parallel plasma transport in the scrape-off layer to a divertor plate. The authors focus on a test problem that has been studied previously, using parameters chosen to model a…

Plasma Physics · Physics 2015-08-18 E. L. Shi , A. H. Hakim , G. W. Hammett

In this contribution I critically revise the alchemical reversible approach in the context of the statistical mechanics theory of non covalent bonding in drug receptor systems. I show that most of the pitfalls and entanglements for the…

Biomolecules · Quantitative Biology 2016-06-29 Piero Procacci

This paper introduces the \emph{serial-parallel decision problem}. Consider an online scheduler that receives a series of tasks, where each task has both a parallel and a serial implementation. The parallel implementation has the advantage…

Data Structures and Algorithms · Computer Science 2024-05-21 William Kuszmaul , Alek Westover

We report the results of intensive numerical calculations for four atomic H2+H2 energy transfer collision. A parallel computing technique based on LAM/MPI functions is used. In this algorithm, the data is distributed to the processors…

Chemical Physics · Physics 2007-05-23 Renat A. Sultanov , Mark Nordby , Dennis Guster

Dissipation and adhesion are important in many areas of materials science, including friction and lubrication, cold spray deposition, and micro-electromechanical systems (MEMS). Another interesting problem is the adhesion of mineral grains…

Materials Science · Physics 2022-05-06 Baochi Doan , Patrick K. Schelling

The nonequilibrium free energy theorems show how distributions of work along nonequilibrium paths are related to free energy differences between the equilibrium states at the end points of these paths. In this paper we develop a natural way…

Statistical Mechanics · Physics 2011-11-09 Stephen R. Williams , Debra J. Searles , Denis J. Evans

Recently, task-based programming models have emerged as a prominent alternative among shared-memory parallel programming paradigms. Inherently asynchronous, these models provide native support for dynamic load balancing and incorporate data…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-09-01 Nicolas Guidotti , Pedro Ceyrat , João Barreto , José Monteiro , Rodrigo Rodrigues , Ricardo Fonseca , Xavier Martorell , Antonio J. Peña

We consider the problem of sampling a high dimensional multimodal target probability measure. We assume that a good proposal kernel to move only a subset of the degrees of freedoms (also known as collective variables) is known a priori.…

Statistical Mechanics · Physics 2025-02-07 Christoph Schönle , Marylou Gabrié , Tony Lelièvre , Gabriel Stoltz

There are two halves to RL systems: experience collection time and policy learning time. For a large number of samples in rollouts, experience collection time is the major bottleneck. Thus, it is necessary to speed up the rollout generation…

Machine Learning · Computer Science 2019-01-29 Tianbing Xu , Andrew Zhang , Liang Zhao

We evaluate the grand potential of a cluster of two molecular species, equivalent to its free energy of formation from a binary vapour phase, using a nonequilibrium molecular dynamics technique where guide particles, each tethered to a…

Statistical Mechanics · Physics 2016-07-12 Jamie Y. Parkinson , Gabriel V. Lau , Ian J. Ford