Related papers: Analysis of a non local model for spontaneous cell…
We study the dynamics of a one-dimensional non-linear and non-local drift-di usion equation set in the half-line, with the coupling involving the trace value on the boundary. The initial mass M of the density determines the behaviour of the…
We investigate the one-dimensional Keller-Segel model where the diffusion is replaced by a non-local operator, namely the fractional diffusion with exponent $0<\alpha\leq 2$. We prove some features related to the classical two-dimensional…
We consider a model of cell motion with boundary signal production which describes some aspects of eukaryotic cell migration. Generic polarity markers located in the cell are transported by actin which they help to polymerize. This leads to…
A parabolic-parabolic (Patlak-) Keller-Segel model in up to three space dimensions with nonlinear cell diffusion and an additional nonlinear cross-diffusion term is analyzed. The main feature of this model is that there exists a new entropy…
When it is polarised, a cell develops an asymmetric distribution of specific molecular markers, cytoskeleton and cell membrane shape. Polarisation can occur spontaneously or be triggered by external signals, like gradients of signalling…
We consider a parabolic non-local free boundary problem that has been derived as a limit of a bulk-surface reaction-diffusion system which models cell polarization. The authors have justified the well-posedness of this problem and have…
The Keller-Segel model is a system of partial differential equations modelling chemotactic aggregation in cellular systems. This model has blowing up solutions for large enough initial conditions in dimensions d >= 2, but all the solutions…
A cell is polarised when it has developed a main axis of organisation through the reorganisation of its cytosqueleton and its intracellular organelles. Polarisation can occur spontaneously or be triggered by external signals, like gradients…
This paper aims to develop numerical approximations of the Keller--Segel equations that mimic at the discrete level the lower bounds and the energy law of the continuous problem. We solve these equations for two unknowns: the organism (or…
We propose a model for cell polarization as a response to an external signal which results in a system of PDEs for different variants of a protein on the cell surface and interior respectively. We study stationary states of this model in…
In this paper, we analyze the dynamics of an $N$ particles system evolving according the gradient flow of an energy functional. The particle system is a consistent approximation of the Lagrangian formulation of a one parameter family of…
A Keller-Segel model describes macroscopic dynamics of bacterial colonies and biological cells. Bacteria secret chemical which attracts other bacteria so that they move towards chemical gradient creating nonlocal attraction between…
We develop and analyse a discrete, one-dimensional model of cell motility which incorporates the effects of volume filling, cell-to-cell adhesion and chemotaxis. The formal continuum limit of the model is a nonlinear generalisation of the…
We investigate in this note the dynamics of a one-dimensional Keller-Segel type model on the half-line. On the contrary to the classical configuration, the chemical production term is located on the boundary. We prove, under suitable…
Cell polarity refers to the spatial asymmetry of molecules on the cell membrane. Altschuler, Angenent, Wang and Wu have proposed a stochastic model for studying the emergence of polarity in the presence of feedback between molecules. We…
This paper is devoted to the analysis of the classical Keller-Segel system over $\mathbb{R}^d$, $d\geq 3$. We describe as much as possible the dynamics of the system characterized by various criteria, both in the parabolic-elliptic case and…
The aim of this paper is to analyze a model for chemotaxis based on a local sensing mechanism instead of the gradient sensing mechanism used in the celebrated minimal Keller-Segel model. The model we study has the same entropy as the…
We consider the parabolic-elliptic Keller-Segel system in three dimensions and higher, corresponding to the mass supercritical case. We construct rigorously a solution which blows up in finite time by having its mass concentrating near a…
The motion of a eukaryotic cell presents a variety of interesting and challenging problems from both a modeling and a computational perspective. The processes span many spatial scales (from molecular to tissue) as well as disparate time…
We study the possibility of non-simultaneous blow-up for positive solutions of a coupled system of two semilinear equations, $u_t = J*u-u+ u^\alpha v^p$, $v_t =\Delta v^+u^qv^\beta$, $p, q, \alpha, \beta>0$ with homogeneous Dirichlet…