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Oscillatory behavior is ubiquitous in many natural and engineered systems, often emerging through self-regulating mechanisms. In this paper, we address the challenge of stabilizing a desired oscillatory pattern in a networked system where…

Systems and Control · Electrical Eng. & Systems 2025-02-05 Luis Guillermo Venegas-Pineda , Hildeberto Jardón-Kojakhmetov , Ming Cao

The problem of controlling complex networks is of interest to disciplines ranging from biology to swarm robotics. However, controllability can be too strict a condition, failing to capture a range of desirable behaviors. Herdability, which…

Systems and Control · Computer Science 2018-05-01 Sebastian F. Ruf , Magnus Egersted , Jeff S. Shamma

Complex networks have been shown to be robust against random structural perturbations, but vulnerable against targeted attacks. Robustness analysis usually simulates the removal of individual or sets of nodes, followed by the assessment of…

Molecular Networks · Quantitative Biology 2012-11-13 Oriol Güell , Francesc Sagués , Georg Basler , Zoran Nikoloski , M. Ángeles Serrano

It is a challenge to predict the response of a large, complex system to a perturbation. Recent attempts to predict the behaviour of food webs have revealed that the effort needed to understand a system grows quickly with its complexity,…

Populations and Evolution · Quantitative Biology 2013-11-07 Helge Aufderheide , Lars Rudolf , Thilo Gross , Kevin D. Lafferty

Systematic relations between multiple objects that occur in various fields can be represented as networks. Real-world networks typically exhibit complex topologies whose structural properties are key factors in characterizing and further…

Physics and Society · Physics 2021-04-09 Yoshihisa Tanaka , Ryosuke Kojima , Shoichi Ishida , Fumiyoshi Yamashita , Yasushi Okuno

Random networks are a powerful tool in the analytical modeling of complex networks as they allow us to write approximate mathematical models for diverse properties and behaviors of networks. One notable shortcoming of these models is that…

Physics and Society · Physics 2023-07-10 Laurent Hébert-Dufresne , Márton Pósfai , Antoine Allard

A characteristic property of networks is their ability to propagate influences, such as infectious diseases, behavioral changes, and failures. An especially important class of such contagious dynamics is that of cascading processes. These…

Physics and Society · Physics 2017-01-26 Adilson E. Motter , Yang Yang

Dysregulation in signal transduction pathways can lead to a variety of complex disorders, including cancer. Computational approaches such as network analysis are important tools to understand system dynamics as well as to identify critical…

Molecular Networks · Quantitative Biology 2015-11-12 Bhanwar Lal Puniya , Laura Allen , Colleen Hochfelder , Mahbubul Majumder , Tomáš Helikar

The capacity of cells and organisms to respond to challenging conditions in a repeatable manner is limited by a finite repertoire of pre-evolved adaptive responses. Beyond this capacity, cells can use exploratory dynamics to cope with a…

Molecular Networks · Quantitative Biology 2017-07-05 Hallel I. Schreier , Yoav Soen , Naama Brenner

Compositionality is a key strategy for addressing combinatorial complexity and the curse of dimensionality. Recent work has shown that compositional solutions can be learned and offer substantial gains across a variety of domains, including…

Machine Learning · Computer Science 2019-04-30 Clemens Rosenbaum , Ignacio Cases , Matthew Riemer , Tim Klinger

Modeling biological networks serves as both a major goal and an effective tool of systems biology in studying mechanisms that orchestrate the activities of gene products in cells. Biological networks are context specific and dynamic in…

Molecular Networks · Quantitative Biology 2014-02-20 Ye Tian , Bai Zhang , Eric P. Hoffman , Robert Clarke , Zhen Zhang , Ie-Ming Shih , Jianhua Xuan , David M. Herrington , Yue Wang

The human brain is the gold standard of adaptive learning. It not only can learn and benefit from experience, but also can adapt to new situations. In contrast, deep neural networks only learn one sophisticated but fixed mapping from inputs…

Computer Vision and Pattern Recognition · Computer Science 2021-03-18 Shixian Wen , Amanda Rios , Yunhao Ge , Laurent Itti

This thesis is a compendium of research which brings together ideas from the fields of Complex Networks and Computational Neuroscience to address two questions regarding neural systems: 1) How the activity of neurons, via synaptic changes,…

Neurons and Cognition · Quantitative Biology 2013-02-19 Samuel Johnson

Many complex networks depend upon biological entities for their preservation. Such entities, from human cognition to evolution, must first encode and then replicate those networks under marked resource constraints. Networks that survive are…

Physics and Society · Physics 2021-03-02 Christopher W. Lynn , Danielle S. Bassett

Inferring network topology from dynamical observations is a fundamental problem pervading research on complex systems. Here, we present a simple, direct method to infer the structural connection topology of a network, given an observation…

Chaotic Dynamics · Physics 2015-05-19 Srinivas Gorur Shandilya , Marc Timme

Biochemical networks are used in computational biology, to model the static and dynamical details of systems involved in cell signaling, metabolism, and regulation of gene expression. Parametric and structural uncertainty, as well as…

Molecular Networks · Quantitative Biology 2014-10-15 Ovidiu Radulescu , Alexander N. Gorban , Andrei Zinovyev , Vincent Noel

Catastrophic failures are complete and sudden collapses in the activity of large networks such as economics, electrical power grids and computer networks, which typically require a manual recovery process. Here we experimentally show that…

Neurons and Cognition · Quantitative Biology 2017-07-21 Shira Sardi , Amir Goldental , Hamutal Amir , Roni Vardi , Ido Kanter

The relation between network structure and dynamics is determinant for the behavior of complex systems in numerous domains. An important long-standing problem concerns the properties of the networks that optimize the dynamics with respect…

Adaptation and Self-Organizing Systems · Physics 2017-12-07 Takashi Nishikawa , Jie Sun , Adilson E. Motter

The ability to effectively control brain dynamics holds great promise for the enhancement of cognitive function in humans, and the betterment of their quality of life. Yet, successfully controlling dynamics in neural systems is challenging,…

Quantitative Methods · Quantitative Biology 2018-08-29 Evelyn Tang , Danielle S. Bassett

The inverse statistical problem of finding direct interactions in complex networks is difficult. In the natural sciences, well-controlled perturbation experiments are widely used to probe the structure of complex networks. However, our…

Disordered Systems and Neural Networks · Physics 2019-10-24 Jialong Jiang , David A. Sivak , Matt Thomson