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Related papers: Towards Modeling HIV Long Term Behavior

200 papers

Recent clinical studies have shown that HIV disease pathogenesis can depend strongly on many factors at the time of transmission, including the strength of the initial viral load and the local availability of CD4+ T-cells. In this article,…

Populations and Evolution · Quantitative Biology 2019-10-15 Stephen Pankavich , Nathan Neri , Deborah Shutt

In this article, we consider an HIV/AIDS epidemic model with four classes of individuals. We have discussed about basic properties of the system and found the basic reproduction number $R_0$ of the system. The stability analysis of the…

Dynamical Systems · Mathematics 2023-04-18 Nouar Chorfi , Salem Abdelmalek , Samir Bendoukha

HIV-1 can disseminate between susceptible cells by two mechanisms: cell-free infection following fluid-phase diffusion of virions and by highly-efficient direct cell-to-cell transmission at immune cell contacts. The contribution of this…

Populations and Evolution · Quantitative Biology 2024-01-02 Changwang Zhang , Shi Zhou , Elisabetta Groppelli , Pierre Pellegrino , Ian Williams , Persephone Borrow , Benjamin M. Chain , Clare Jolly

Oxidative stress, a reaction caused by the imbalance between the reactive oxygen species of human organism and its ability to detoxify reactive intermediates and to repair the resulting damage plays an important role in HIV-infections. On…

Populations and Evolution · Quantitative Biology 2018-08-08 Shaoli Wang , Fei Xu , Xinyu Song

We introduce a model for the evolution of sexually transmitted diseases, in which the social behavior is incorporated as a determinant factor for the further propagation of the infection. The system may be regarded as a society of agents…

Statistical Mechanics · Physics 2009-11-07 Sebatian Goncalves , Marcelo Kuperman

We propose and investigate a delayed model that studies the relationship between HIV and the immune system during the natural course of infection and in the context of antiviral treatment regimes. Sufficient criteria for local asymptotic…

Optimization and Control · Mathematics 2018-03-19 Diana Rocha , Cristiana J. Silva , Delfim F. M. Torres

The search to understand how the HIV virus spreads inside the human body and how the immune response works to control it has motivated studies related to Mathematical Immunology. Actually, researches include the idea of mathematical models…

Populations and Evolution · Quantitative Biology 2016-01-19 Marcelo Margon Rossi , Luis Fernandez Lopez

We establish a stochastic HIV/AIDS model for the individuals with protection awareness and reveal how the protection awareness plays its important role in the control of AIDS. We firstly show that there exists a global positive solution for…

Dynamical Systems · Mathematics 2023-03-01 Xuanpei Zhai , Wenshuang Li , Fengying Wei , Xuerong Mao

We make a mathematical analysis of an age structured HIV infection model with both virus-to-cell and cell-to-cell transmissions to understand the dynamical behavior of HIV infection in vivo. In the model, we consider the proliferation of…

Populations and Evolution · Quantitative Biology 2018-09-26 Xiangming Zhang , Zhihua Liu

HIV/AIDs Regimen specification one of many problems for which bioinformaticians have implemented and trained machine learning methods such as neural networks. Predicting HIV resistance would be much easier, but unfortunately we rarely have…

Computers and Society · Computer Science 2009-12-22 P. Balasubramanie , M. Lilly Florence

The control of opportunistic infections among HIV infected individuals should be one of the major public health concerns in reducing mortality rate of individuals living with HIV/AIDS. In this study a deterministic co-infection mathematical…

Dynamical Systems · Mathematics 2024-08-02 Michael Byamukama , Damian Kajunguri , Martin Karuhanga

In this paper, we develop a dynamic model of HIV infection that incorporates latent hosts, cytotoxic T lymphocyte (CTL) immunity, saturated incidence rates, and two transmission mechanisms: virus-to-cell and cell-to-cell transmission. The…

Dynamical Systems · Mathematics 2025-11-25 Songbo Hou , Xinxin Tian

An investigation was conducted to study the robustness of the results obtained from the cellular automata model which describes the spread of the HIV infection within lymphoid tissues [R. M. Zorzenon dos Santos and S. Coutinho, Phys. Rev.…

Biological Physics · Physics 2008-07-21 P. H. Figueirêdo , S. Coutinho , R. M. Zorzenon dos Santos

We propose a population model for TB-HIV/AIDS coinfection transmission dynamics, which considers antiretroviral therapy for HIV infection and treatments for latent and active tuberculosis. The HIV-only and TB-only sub-models are analyzed…

Optimization and Control · Mathematics 2015-04-16 Cristiana J. Silva , Delfim F. M. Torres

In [Math. Comput. Sci. 12 (2018), no. 2, 111--127], a delayed model describing the dynamics of the Human Immunodeficiency Virus (HIV) with Cytotoxic T Lymphocytes (CTL) immune response is investigated by Allali, Harroudi and Torres. Here,…

Dynamical Systems · Mathematics 2022-10-03 Sandra Vaz , Delfim F. M. Torres

We propose a time-parameterized analogy between the thermodynamic behavior of a 3-level energy system and the progression of the HIV infection described by the cell population evolution generated by an appropriated cellular automata model.…

Populations and Evolution · Quantitative Biology 2020-06-24 Ramón E. R. González , P. H. Figueirêdo , S. Coutinho

We revisit the SICA (Susceptible-Infectious-Chronic-AIDS) mathematical model for transmission dynamics of the human immunodeficiency virus (HIV) with varying population size in a homogeneously mixing population. We consider SICA models…

Populations and Evolution · Quantitative Biology 2020-08-10 Cristiana J. Silva , Delfim F. M. Torres

We propose a fractional order model for HIV/AIDS transmission. Local and uniform stability of the fractional order model is studied. The theoretical results are illustrated through numerical simulations.

Optimization and Control · Mathematics 2019-06-07 Cristiana J. Silva , Delfim F. M. Torres

A virologic marker, the number of HIV RNA copies or viral load, is currently used to evaluate antiretroviral (ARV) therapies in AIDS clinical trials. This marker can be used to assess the ARV potency of therapies, but is easily affected by…

Applications · Statistics 2009-01-27 Yangxin Huang , Tao Lu

We study the relation between different social behaviors and the onset of epidemics in a model for the dynamics of sexual transmitted diseases. The model considers the society as a system of individual sexuated agents that can be organized…

Adaptation and Self-Organizing Systems · Physics 2009-11-10 Sebastian Goncalves , Marcelo Kuperman , Marcelo Ferreira da Costa Gomes