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We study molecular dynamics within populations of diffusively coupled cells under the assumption of fast diffusive exchange. As a technical tool, we propose conditions on boundedness and ultimate boundedness for systems with a singular…
In this document, we deal with the stabilization problem of slow-fast systems (or singularly perturbed Ordinary Differential Equations) at a non-hyperbolic point. The class of systems studied here have the following properties: 1) they have…
On the basis of a mathematical model, we continue the study of the metabolic Krebs cycle (or the tricarboxilic acid cycle). For the first time, we consider its consistency and stability, which depend on the dissipation of a transmembrane…
Clusters of IP3 receptor channels in the membranes of the endoplasmic reticulum (ER) of many non-excitable cells release calcium ions in a cooperative manner giving rise to dynamical patterns such as Ca2+ puffs, waves, and oscillations that…
In this work we show that given a nonlinear programming problem, it is possible to construct a family of dynamical systems defined on the feasible set of the given problem, so that: (a) the equilibrium points are the unknown critical points…
In the context of linear control systems, a commonly-held intuition is that negative and positive feedback cannot both be stability enhancing. The canonical linear prototype is the scalar system $\dot x=u$ which, under negative linear…
The stability of heteroclinic cycles may be obtained from the value of the local stability index along each connection of the cycle. We establish a way of calculating the local stability index for quasi-simple cycles: cycles whose…
This paper investigates the decentralized stabilization problem for a class of interconnected systems in the presence of non-triangular structural uncertainties and time-varying parameters, where each subsystem exchanges information only…
For the discrete-time dynamical system generated by the Poincare map T of a time-periodic closed-loop negative feedback system, we present an amenable condition which enables us to obtain the global convergence of the orbits. This yields…
A fundamental aspect of the three-body problem is its stability. Most stability studies have focused on the co-planar three-body problem, deriving analytic criteria for the dynamical stability of such pro/retrograde systems. Numerical…
Feedback loops are essential for regulating cell proliferation and maintaining the delicate balance between cell division and cell death. Thanks to the exact solution of a few simple models of cell growth it is by now clear that stochastic…
Dynamical properties of tropically discretized and max-plus negative feedback models are investigated. Reviewing the previous study [S. Gibo and H. Ito, J. Theor. Biol. 378, 89 (2015)], the conditions under which the Neimark-Sacker…
This paper develops a sequential-linearization feedback optimization framework for driving nonlinear dynamical systems to an optimal steady state. A fundamental challenge in feedback optimization is the requirement of accurate first-order…
This paper addresses the design of robust dynamic output feedback control for highly uncertain systems in which the unknown disturbance might be excited by the derivative of the control input. This context appears in many industrial…
This paper studies the periodic feedback stabilization for a class of linear $T$-periodic evolution equations.Several equivalent conditions on the linear periodic feedback stabilization are obtained. These conditions are related with the…
We examine the stability of hierarchical triple systems using direct $N$-body simulations without adopting a secular perturbation approximation. We estimate their disruption timescales in addition to the mere stable/unstable criterion, with…
In this paper, the dynamics of a phytoplankton-zooplankton system with linear functional responses are examined. For the continuous-time model, the global asymptotic stability of the fixed points is demonstrated by constructing Lyapunov…
The problem of maintaining the output of a positive time-invariant single-input single-output system within a predefined corridor of values is treated. For third-order plants possessing a certain structure, it is proven that the problem is…
In the paper below we consider a problem of stabilization of a priori unknown unstable periodic orbits in non-linear autonomous discrete dynamical systems. We suggest a generalization of a non-linear DFC scheme to improve the rate of…
In this Letter we show how the nonlinear evolution of a resonant triad depends on the special combination of the modes' phases chosen according to the resonance conditions. This phase combination is called dynamical phase. Its evolution is…