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Related papers: Loose mechanochemical coupling of molecular motors

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Molecular motors convert chemical energy into mechanical work while operating in an environment dominated by Brownian motion. The aim of this paper is to explore the flow of energy between the molecular motors and its surroundings, in…

Statistical Mechanics · Physics 2011-05-06 Yunxin Zhang

Molecular motors transduce chemical energy obtained from hydrolizing ATP into mechanical work exerted against an external force. We calculate their efficiency at maximum power output for two simple generic models and show that the…

Statistical Mechanics · Physics 2009-11-13 Tim Schmiedl , Udo Seifert

A molecular motor is made of either a single macromolecule or a macromolecular complex. Just like their macroscopic counterparts, molecular motors "transduce" input energy into mechanical work. All the nano-motors considered here operate…

Biological Physics · Physics 2013-07-18 Debashish Chowdhury

Biological functions in each animal cell depend on coordinated operations of a wide variety of molecular motors. Some of the these motors transport cargo to their respective destinations whereas some others are mobile workshops which…

Biological Physics · Physics 2008-03-07 Debashish Chowdhury

Routinely navigating through an ever-changing and unsteady environment, and utilizing chemical energy, molecular motors transport the cell's crucial components, such as neurotransmitters and organelles. They generate force and pull cargo,…

Biological Physics · Physics 2012-09-28 Bartosz Lisowski , Michał Żabicki

A simple model of the two-state ratchet type is proposed for molecular chemical engines that convert chemical free energy into mechanical work and vice versa. The engine works by catalyzing a chemical reaction and turning a rotor.…

Statistical Mechanics · Physics 2018-05-22 Kazuo Sasaki , Ryo Kanada , Satoshi Amari

We propose a simple theoretical model for a molecular chemical engine that catalyzes a chemical reaction and converts the free energy released by the reaction into mechanical work. Binding and unbinding processes of reactant and product…

Statistical Mechanics · Physics 2018-05-22 Kazuo Sasaki

Microscopic biological systems operate far from equilibrium, are subject to strong fluctuations, and are composed of many coupled components with interactions varying in nature and strength. Researchers are actively investigating the…

Statistical Mechanics · Physics 2023-12-25 Emma Lathouwers , David A. Sivak

We study microscopic engines that use a single active particle as their "working medium". Part of the energy required to drive the directed motion of the particle can be recovered as work, even at constant temperature. A wide class of…

Soft Condensed Matter · Physics 2022-01-20 Thomas Speck

The motion of molecular motor is essential to the biophysical functioning of living cells. In principle, this motion can be regraded as a multiple chemical states process. In which, the molecular motor can jump between different chemical…

Biological Physics · Physics 2015-05-19 Yunxin Zhang

Molecular motors transport various cargos along cytoskeletal filaments, analogous to trucks on roads. In contrast to vehicles, however, molecular motors do not work alone but in small teams. We describe a simple model for the transport of a…

Statistical Mechanics · Physics 2008-07-08 Melanie J. I. Müller , Janina Beeg , Rumiana Dimova , Stefan Klumpp , Reinhard Lipowsky

Particles moving in oscillating potential with broken mirror symmetry are considered. We calculate their energetic efficiency, when acting as molecular motors carrying a load against external force. It is shown that interaction between…

Statistical Mechanics · Physics 2010-09-03 Frantisek Slanina

Processive molecular motors which drive the traffic of organelles in cells move in a directed way along cytoskeletal filaments. On large time scales, they perform motor walks, i.e., peculiar random walks which arise from the repeated…

Statistical Mechanics · Physics 2007-05-23 Stefan Klumpp , Theo M. Nieuwenhuizen , Reinhard Lipowsky

The output of a motor is work, while the output of a clock is information. Here it is discussed how a molecular motor can produce both, work and information, depending on the load. If the ratio of the backward and forward stepping rates of…

Chemical Physics · Physics 2022-04-13 Henry Hess

Chemical gradients provide the primordial energy for biological functions by driving the mechanical movement of microscopic engines. Their thermodynamic properties remain elusive, especially concerning the dynamic change in energy demand in…

Statistical Mechanics · Physics 2025-04-01 Ruo-Xun Zhai , Hui Dong

Understanding the operation of biological molecular motors, nanoscale machines that transduce electrochemical energy into mechanical work, is enhanced by bottom-up strategies to synthesize novel motors.

Biological Physics · Physics 2017-05-15 Chapin Korosec , Nancy R. Forde

In many biological systems localized mechanical information is transmitted by mechanically neutral chemical signals. Typical examples include contraction waves in acto-myosin cortex at cellular scale and peristaltic waves at tissue level.…

Soft Condensed Matter · Physics 2025-11-25 Lev Truskinovsky , Giuseppe Zurlo

Recent experiments reveal both passive subdiffusion of various nanoparticles and anomalous active transport of such particles by molecular motors in the molecularly crowded environment of living biological cells. Passive and active…

Biological Physics · Physics 2014-03-24 Igor Goychuk , Vasyl O. Kharchenko , R. Metzler

Living systems efficiently use chemical fuel to do work, process information, and assemble patterns despite thermal noise. Whether high efficiency arises from general principles or specific fine-tuning is unknown. Here, applying a recent…

Biological Physics · Physics 2022-10-11 Milo M Lin

Molecular motors perform active movements along cytoskeletal filaments and drive the traffic of organelles and other cargo particles in cells. In contrast to the macroscopic traffic of cars, however, the traffic of molecular motors is…

Statistical Mechanics · Physics 2009-12-04 Stefan Klumpp , Melanie J. I. Müller , Reinhard Lipowsky
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