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Evolutionary branching is analysed in a stochastic, individual-based population model under mutation and selection. In such models, the common assumption is that individual reproduction and life career are characterised by values of a…

Populations and Evolution · Quantitative Biology 2025-10-01 S. Sagitov , B. Mehlig , P. Jagers , V. Vatutin

The random walk process in a nonhomogeneous medium, characterised by a L\'evy stable distribution of jump length, is discussed. The width depends on a position: either before the jump or after that. In the latter case, the density slope is…

Statistical Mechanics · Physics 2017-03-29 Tomasz Srokowski

Large sets of genotypes give rise to the same phenotype because phenotypic expression is highly redundant. Accordingly, a population can accept mutations without altering its phenotype, as long as thegenotype mutates into another one on the…

Populations and Evolution · Quantitative Biology 2015-02-18 Susanna Manrubia , José A. Cuesta

Genetic diversity is central to the process of evolution. Both natural selection and random genetic drift are influenced by the level of genetic diversity of a population; selection acts on diversity while drift samples from it. At a given…

Populations and Evolution · Quantitative Biology 2024-11-12 Nikolas Vellnow , Toni I. Gossmann , David Waxman

We study a minimal model for the growth of a phenotypically heterogeneous population of cells subject to a fluctuating environment in which they can replicate (by exploiting available resources) and modify their phenotype within a given…

Populations and Evolution · Quantitative Biology 2019-01-23 Andrea De Martino , Thomas Gueudré , Mattia Miotto

Evolution depends on the fitness of organisms, the expected rate of reproducing. Directly getting offspring is the most basic form of fitness, but fitness can also be increased indirectly by helping genetically related individuals (such as…

Populations and Evolution · Quantitative Biology 2015-12-17 J. H. van Hateren

A population evolving in an inhomogeneous environment will adapt differently to different regions. We study the conditions under which such a population can maintain adaptations to a particular region when that region is not stationary, but…

Populations and Evolution · Quantitative Biology 2007-05-23 Michael M. Desai , David R. Nelson

Natural selection drives populations towards higher fitness, but crossing fitness valleys or plateaus may facilitate progress up a rugged fitness landscape involving epistasis. We investigate quantitatively the effect of subdividing an…

Populations and Evolution · Quantitative Biology 2014-08-18 Anne-Florence Bitbol , David J. Schwab

The genetic diversity of a species is shaped by its recent evolutionary history and can be used to infer demographic events or selective sweeps. Most inference methods are based on the null hypothesis that natural selection is a weak or…

Populations and Evolution · Quantitative Biology 2013-03-05 Richard A. Neher , Oskar Hallatschek

The dynamics of populations is rich, taking into account that both, the individual's actions and the population's fitness are coupled. The way in which an individual chooses a strategy depends off course on the interaction with other…

Biological Physics · Physics 2007-07-20 Juan G. Diaz Ochoa

The tempo and mode of an adaptive process is strongly determined by the structure of the fitness landscape that underlies it. In order to be able to predict evolutionary outcomes (even on the short term), we must know more about the nature…

Populations and Evolution · Quantitative Biology 2013-02-28 Bjørn Østman , Christoph Adami

A simulation model of a population having internal (genetic) structure is presented. The population is subject to selection pressure coming from the environment which is the same in the whole system but changes in time. Reproduction has a…

Adaptation and Self-Organizing Systems · Physics 2012-08-31 Andrzej Pekalski , Marcel Ausloos

An organism that is newly introduced into an existing population has a survival probability that is dependent on both the population density of its environment and the competition it experiences with the members of that population.…

Populations and Evolution · Quantitative Biology 2024-12-17 Jason M. Gray , Rowan J. Barker-Clarke , Jacob G. Scott , Michael Hinczewski

The mechanisms by which adaptive phenotypes spread within an evolving population after their emergence are understood fairly well. Much less is known about the factors that influence the evolutionary accessibility of such phenotypes, a…

Populations and Evolution · Quantitative Biology 2015-05-13 Wilfred Ndifon , Joshua B. Plotkin , Jonathan Dushoff

Stochastic phenotype switching has been suggested to play a beneficial role in microbial populations by leading to the division of labour among cells, or ensuring that at least some of the population survives an unexpected change in…

Populations and Evolution · Quantitative Biology 2016-02-02 Andrew C. Tadrowski , Martin R. Evans , Bartlomiej Waclaw

Predicting fitness of biologically-active populations, communities or systems in fluctuating environments is a long-standing challenge. Phenotypic plasticity and bet-hedging strategy, two key evolutionary traits living systems harness to…

Populations and Evolution · Quantitative Biology 2024-10-24 Sumana Bhattacharyya , Uttam Singh , Anupam Sengupta

We study the evolution of preferences in multi-population settings that allow matches across distinct populations. Each individual has subjective preferences over potential outcomes, and chooses a best response based on his preferences and…

Computer Science and Game Theory · Computer Science 2024-09-20 Yu-Sung Tu , Wei-Torng Juang

The importance of mutator clones in the adaptive evolution of asexual populations is not fully understood. Here we address this problem by using an ab initio microscopic model of living cells, whose fitness is derived directly from their…

Biomolecules · Quantitative Biology 2009-02-17 Muyoung Heo , Louis Kang , Eugene Shakhnovich

Mounting evidence suggests that natural populations can harbor extensive fitness diversity with numerous genomic loci under selection. It is also known that genealogical trees for populations under selection are quantifiably different from…

Populations and Evolution · Quantitative Biology 2013-01-04 Adel Dayarian , Boris I Shraiman

We compare the speed with which a sexual, respectively an asexual, population is able to respond to a biased selective pressure. Our model focuses on the Weismann hypothesis that the extra variation caused by crossing-over and recombination…

Condensed Matter · Physics 2007-05-23 Kerstin Holmstrom , Henrik Jeldtoft Jensen