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Modeling the time evolution of discrete sets of items (e.g., genetic mutations) is a fundamental problem in many biomedical applications. We approach this problem through the lens of continuous-time Markov chains, and show that the…

Machine Learning · Computer Science 2021-07-08 Alkis Gotovos , Rebekka Burkholz , John Quackenbush , Stefanie Jegelka

We consider large linear and nonlinear fixed point problems, and solution with proximal algorithms. We show that there is a close connection between two seemingly different types of methods from distinct fields: 1) Proximal iterations for…

Numerical Analysis · Computer Science 2019-09-05 Dimitri P. Bertsekas

In cancer research, clustering techniques are widely used for exploratory analyses and dimensionality reduction, playing a critical role in the identification of novel cancer subtypes, often with direct implications for patient management.…

Spatiotemporal data mining aims to discover interesting, useful but non-trivial patterns in big spatial and spatiotemporal data. They are used in various application domains such as public safety, ecology, epidemiology, earth science, etc.…

Databases · Computer Science 2022-06-28 Arun Sharma , Zhe Jiang , Shashi Shekhar

We present a novel probabilistic clustering model for objects that are represented via pairwise distances and observed at different time points. The proposed method utilizes the information given by adjacent time points to find the…

Machine Learning · Computer Science 2015-04-16 Julia E. Vogt , Marius Kloft , Stefan Stark , Sudhir S. Raman , Sandhya Prabhakaran , Volker Roth , Gunnar Rätsch

Background: Current research suggests that a small set of "driver" mutations are responsible for tumorigenesis while a larger body of "passenger" mutations occurs in the tumor but does not progress the disease. Due to recent pharmacological…

Genomics · Quantitative Biology 2013-10-30 Gregory Ryslik , Yuwei Cheng , Kei-Hoi Cheung , Robert Bjornson , Daniel Zelterman , Yorgo Modis , Hongyu Zhao

We study hierarchical clusterings of metric spaces that change over time. This is a natural geometric primitive for the analysis of dynamic data sets. Specifically, we introduce and study the problem of finding a temporally coherent…

Data Structures and Algorithms · Computer Science 2017-10-23 Tamal K. Dey , Alfred Rossi , Anastasios Sidiropoulos

In online video platforms, accurate watch time prediction has become a fundamental and challenging problem in video recommendation. Previous research has revealed that the accuracy of watch time prediction highly depends on both the…

Information Retrieval · Computer Science 2025-08-26 Xiaokai Chen , Xiao Lin , Changcheng Li , Peng Jiang

Clustering techniques are very attractive for extracting and identifying patterns in datasets. However, their application to very large spatial datasets presents numerous challenges such as high-dimensionality data, heterogeneity, and high…

Databases · Computer Science 2018-02-27 Malika Bendechache , Nhien-An Le-Khac , M-Tahar Kechadi

Spectral clustering techniques are valuable tools in signal processing and machine learning for partitioning complex data sets. The effectiveness of spectral clustering stems from constructing a non-linear embedding based on creating a…

Machine Learning · Computer Science 2021-02-02 Farhad Pourkamali-Anaraki

A fine-grained data recipe is crucial for pre-training large language models, as it can significantly enhance training efficiency and model performance. One important ingredient in the recipe is to select samples based on scores produced by…

Computation and Language · Computer Science 2026-01-01 Ziqing Fan , Yuqiao Xian , Yan Sun , Li Shen

We study the problem of list-decodable mean estimation, where an adversary can corrupt a majority of the dataset. Specifically, we are given a set $T$ of $n$ points in $\mathbb{R}^d$ and a parameter $0< \alpha <\frac 1 2$ such that an…

Data Structures and Algorithms · Computer Science 2021-11-15 Ilias Diakonikolas , Daniel M. Kane , Daniel Kongsgaard , Jerry Li , Kevin Tian

Time Series Clustering is an important subroutine in many higher-level data mining analyses, including data editing for classifiers, summarization, and outlier detection. It is well known that for similarity search the superiority of…

Machine Learning · Computer Science 2016-12-05 Nurjahan Begum , Liudmila Ulanova , Hoang Anh Dau , Jun Wang , Eamonn Keogh

We propose a new computational framework that combines the recently developed time-parallel (TP) and the compound wavelet matrix (CWM) methods. The framework, termed tpCWM, offers significant computational acceleration by making…

Computational Physics · Physics 2009-09-29 George Frantziskonis , Krishna Muralidharan , Pierre Deymier , Srdjan Simunovic , Sreekanth Pannala

Matching corresponding features between two images is a fundamental task to computer vision with numerous applications in object recognition, robotics, and 3D reconstruction. Current state of the art in image feature matching has focused on…

Computer Vision and Pattern Recognition · Computer Science 2019-09-05 Chen Zhao , Jiaqi Yang , Ke Xian , Zhiguo Cao , Xin Li

Scientists in many fields have the common and basic need of dimensionality reduction: visualizing the underlying structure of the massive multivariate data in a low-dimensional space. However, many dimensionality reduction methods confront…

Machine Learning · Statistics 2015-03-19 Teng Qiu , Yongjie Li

Quantitative proteomics plays a central role in uncovering regulatory mechanisms, identifying disease biomarkers, and guiding the development of precision therapies. These insights are often obtained through complex Bayesian models, whose…

Quantitative Methods · Quantitative Biology 2025-09-11 Matthew Carter , Lee Devlin , Alexander Philips , Edward Pyzer-Knapp , Paul Spirakis , Simon Maskell

Projective clustering is a problem with both theoretical and practical importance and has received a great deal of attentions in recent years. Given a set of points $P$ in $\mathbb{R}^{d}$ space, projective clustering is to find a set…

Computational Geometry · Computer Science 2015-03-20 Hu Ding , Jinhui Xu

The time series cluster kernel (TCK) provides a powerful tool for analysing multivariate time series subject to missing data. TCK is designed using an ensemble learning approach in which Bayesian mixture models form the base models. Because…

Machine Learning · Computer Science 2019-07-12 Karl Øyvind Mikalsen , Cristina Soguero-Ruiz , Filippo Maria Bianchi , Arthur Revhaug , Robert Jenssen

Rectangular treemaps are often the method of choice to visualize large hierarchical datasets. Nowadays such datasets are available over time, hence there is a need for (a) treemaps that can handle time-dependent data, and (b) corresponding…

Computational Geometry · Computer Science 2020-01-10 Eduardo Vernier , Max Sondag , Joao Comba , Bettina Speckmann , Alexandru Telea , Kevin Verbeek
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