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The expression of survival factors for radiation damaged cells is based on probabilistic assumptions and experimentally fitted for each tumor, radiation and conditions. Here we show how the simplest of these radiobiological models can be…

Quantitative Methods · Quantitative Biology 2015-05-19 Oscar Sotolongo-Grau , Daniel Rodríguez-Pérez , José Carlos Antoranz , Oscar Sotolongo-Costa

A time-dependent statistical description of multiple particle breakage is presented. The approach combines the Tsallis non-extensive entropy with a fractal kinetic equation for the time variation of the number of fragments. The obtained…

Statistical Mechanics · Physics 2014-12-04 Oscar Sotolongo-Costa , Luis Manuel Gaggero-Sager , Miguel Eduardo Mora-Ramos

A mathematical model of radiotherapy is proposed. The study used the classical 24 hours way of fractionation with a weekend pause. We introduce the matrices of ``radiotherapy'' and ``growth''. We developed an equation of the fraction cell…

Dynamical Systems · Mathematics 2007-05-23 K. Malachowski , M. Wolf

The expression of survival factors for radiation damaged cells is empirical and based on probabilistic assumptions. We obtain it either from the maximum entropy principle for the classical Boltzmann-Gibbs entropy and/or from the Tsallis…

It has long been known that radiation biology plays an important role and it is necessary for radiotherapy treatments. The radiation effects on normal and malignant tissues after exposure range from a femtosecond to months and years…

Medical Physics · Physics 2017-04-24 Cyril Voyant , Daniel Julian

Thermodynamical quantities of the blackbody radiation, such as free energy, entropy, total radiation energy, specific heat are calculated within the Tsallis thermostatistics where factorization method is incorparated. It is shown that basic…

Statistical Mechanics · Physics 2007-05-23 F. Buyukkilic , I. Sokmen , D. Demirhan

The form invariance of the statement of the maximum entropy principle and the metric structure in quantum density matrix theory, when generalized to nonextensive situations, is shown here to determine the structure of the nonextensive…

Quantum Physics · Physics 2009-01-23 A. K. Rajagopal , Sumiyoshi Abe

By means of a recently-proposed metric or structural derivative, called scale-q-derivative approach, we formulate differential equation that models the cell death by a radiation exposure in tumor treatments. The considered independent…

Medical Physics · Physics 2017-04-13 José Weberszpil , Oscar Sotolongo-Costa

Examples of joint probability distributions are studied in terms of Tsallis' nonextensive statistics both for correlated and uncorrelated variables, in particular it is explicitely shown how correlations in the system can make Tsallis…

Statistical Mechanics · Physics 2008-11-26 G. Wilk , Z. Wlodarczyk

A study of the effects of non-extensivity on the modelling of atomic physics in hot dense plasmas is proposed within Tsallis' statistics. The electronic structure of the plasma is calculated through an average-atom model based on the…

Plasma Physics · Physics 2015-05-30 Jean-Christophe Pain , Denis Teychenné , Franck Gilleron

We are witnessing the birth of a new variety of pharmacokinetics where non-integer-order differential equations are employed to study the time course of drugs in the body: this is dubbed "fractional pharmacokinetics." The presence of…

Dynamical Systems · Mathematics 2019-04-25 Pantelis Sopasakis , Haralambos Sarimveis , Panos Macheras , Aristides Dokoumetzidis

The nonextensive statistical ensembles are revisited for the complex systems with long-range interactions and long-range correlations. An approximation, the value of nonextensive parameter (1-q) is assumed to be very tiny, is adopted for…

Statistical Mechanics · Physics 2020-02-26 Yahui Zheng , Jiulin Du , Linxia Liu , Huijun Kong

Based on the Tsallis entropy, the nonextensive thermodynamic properties are studied as a q-deformation of classical statistical results using only probabilistic methods and straightforward calculations. It is shown that the constant in the…

Statistical Mechanics · Physics 2007-05-23 Franck Jedrzejewski

Gibbs-Boltzmann entropy leads to systems that have a strong dependence on initial conditions. In reality, most materials behave quite independently of initial conditions. Nonextensive entropy or Tsallis entropy leads to nonextensive…

Statistical Mechanics · Physics 2022-07-01 Saman Amiri , Mahdi Mirzaee , Mohammad Mazhari

The Tsallis entropy, which is a generalization of the Boltzmann-Gibbs entropy, plays a central role in nonextensive statistical mechanics of complex systems. A lot of efforts have recently been made on establishing a dynamical foundation…

Statistical Mechanics · Physics 2009-11-11 Sumiyoshi Abe , Yutaka Nakada

The role played by non extensive thermodynamics in physical systems has been under intense debate for the last decades. With many applications in several areas, the Tsallis statistics has been discussed in details in many works and…

Statistical Mechanics · Physics 2018-10-17 Airton Deppman , Eugenio Megias , Debora P. Menezes , Tobias Frederico

There is evidence that the population of cells that experience fluctuating oxygen levels are more radioresistant than chronically hypoxic ones and hence, this population may determine radiotherapy (RT) response, in particular for…

Medical Physics · Physics 2023-03-28 Edward Taylor

Non-extensive statistical physics has allowed to generalize mathematical functions such as exponential and logarithms. The same framework is used to generalize sum and product so that the operations allow a more fluid way to work with…

Biological Physics · Physics 2009-08-19 O. Sotolongo-Grau , D. Rodriguez-Perez , J. C. Antoranz , Oscar Sotolongo-Costa

This paper studies the identification of causal effects of a continuous treatment using a new difference-in-difference strategy. Our approach allows for endogeneity of the treatment, and employs repeated cross-sections. It requires an…

Econometrics · Economics 2023-04-18 Xavier D'Haultfoeuille , Stefan Hoderlein , Yuya Sasaki

This is a study of the information evolution of complex systems by geometrical consideration. We look at chaotic systems evolving in fractal phase space. The entropy change in time due to the fractal geometry is assimilated to the…

Statistical Mechanics · Physics 2009-11-10 Q. A. Wang , L. Nivanen , A. Le Mehaute , M. Pezeril
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