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Novel radiotherapy techniques like synchrotron X-ray microbeam radiation therapy (MRT), require fast dose distribution predictions that are accurate at the sub-mm level, especially close to tissue/bone/air interfaces. Monte Carlo physics…

The Distributed Electronic Cosmic-ray Observatory (DECO) is a cell phone app that uses a cell phone camera image sensor to detect cosmic-ray particles and particles from radioactive decay. Images recorded by DECO are classified by a…

Instrumentation and Methods for Astrophysics · Physics 2023-11-30 Runze Li , Alex Pizzuto , Justin Vandenbroucke , Brent Mode

The XIFU X-ray spectrometer instrument on the future Athena mission needs X-ray calibration sources to calibrate the gains of the individual detector pixels. For this purpose, electronically controlled Modulated X-ray Sources (MXS) are…

Instrumentation and Methods for Astrophysics · Physics 2018-06-21 C. P. de Vries , V. Fioretti , J. W. den Herder , E Schyns , S. D. Pinto

Monte-Carlo simulations of a focusing supermirror guide after the monochromator on the IN14 cold neutron three-axis spectrometer, I.L.L. were carried out using the instrument simulation programs RESTRAX and McSTAS. The simulations were…

Materials Science · Physics 2009-10-31 A. R. Wildes , J. Saroun , E. Farhi , I. Anderson , P. Hoghoj , A. Brochier

Calorimeters with a high granularity are a fundamental requirement of the Particle Flow paradigm. This paper focuses on the prototype of a hadron calorimeter with analog readout, consisting of thirty-eight scintillator layers alternating…

Instrumentation and Detectors · Physics 2014-06-17 C. Adloff , J. Blaha , J. -J. Blaising , C. Drancourt , A. Espargilière , R. Gaglione , N. Geffroy , Y. Karyotakis , J. Prast , G. Vouters , K. Francis , J. Repond , J. Schlereth , J. Smith , L. Xia , E. Baldolemar , J. Li , S. T. Park , M. Sosebee , A. P. White , J. Yu , T. Buanes , G. Eigen , Y. Mikami , N. K. Watson , G. Mavromanolakis , M. A. Thomson , D. R. Ward , W. Yan , D. Benchekroun , A. Hoummada , Y. Khoulaki , J. Apostolakis , A. Dotti , G. Folger , V. Ivantchenko , V. Uzhinskiy , M. Benyamna , C. Cârloganu , F. Fehr , P. Gay , S. Manen , L. Royer , G. C. Blazey , A. Dyshkant , J. G. R. Lima , V. Zutshi , J. -Y. Hostachy , L. Morin , U. Cornett , D. David , G. Falley , K. Gadow , P. Göttlicher , C. Günter , B. Hermberg , S. Karstensen , F. Krivan , A. -I. Lucaci-Timoce , S. Lu , B. Lutz , S. Morozov , V. Morgunov , M. Reinecke , F. Sefkow , P. Smirnov , M. Terwort , A. Vargas-Trevino , N. Feege , E. Garutti , I. Marchesinik , M. Ramilli , P. Eckert , T. Harion , A. Kaplan , H. -Ch. Schultz-Coulon , W. Shen , R. Stamen , B. Bilki , E. Norbeck , Y. Onel , G. W. Wilson , K. Kawagoe , P. D. Dauncey , A. -M. Magnan , V. Bartsch , M. Wing , F. Salvatore , E. Calvo Alamillo , M. -C. Fouz , J. Puerta-Pelayo , B. Bobchenko , M. Chadeeva , M. Danilov , A. Epifantsev , O. Markin , R. Mizuk , E. Novikov , V. Popov , V. Rusinov , E. Tarkovsky , N. Kirikova , V. Kozlov , P. Smirnov , Y. Soloviev , P. Buzhan , A. Ilyin , V. Kantserov , V. Kaplin , A. Karakash , E. Popova , V. Tikhomirov , C. Kiesling , K. Seidel , F. Simon , C. Soldner , M. Szalay , M. Tesar , L. Weuste , M. S. Amjad , J. Bonis , S. Callier , S. Conforti di Lorenzo , P. Cornebise , Ph. Doublet , F. Dulucq , J. Fleury , T. Frisson , N. van der Kolk , H. Li , G. Martin-Chassard , F. Richard , Ch. de la Taille , R. Pöschl , L. Raux , J. Rouëné , N. Seguin-Moreau , M. Anduze , V. Boudry , J-C. Brient , D. Jeans , P. Mora de Freitas , G. Musat , M. Reinhard , M. Ruan , H. Videau , B. Bulanek , J. Zacek , J. Cvach , P. Gallus , M. Havranek , M. Janata , J. Kvasnicka , D. Lednicky , M. Marcisovsky , I. Polak , J. Popule , L. Tomasek , M. Tomasek , P. Ruzicka , P. Sicho , J. Smolik , V. Vrba , J. Zalesak , B. Belhorma , H. Ghazlane , T. Takeshita , S. Uozumi , M. Götze , O. Hartbrich , J. Sauer , S. Weber , C. Zeitnitz

Background: FLASH radiotherapy is a treatment regime that delivers therapeutic dose to tumors at an ultra-high dose rate while maintaining adequate normal tissue sparing. However, a comprehensive understanding of the underlying mechanisms,…

Alignment of the ILC main linac will be more critical than for any currently existing accelerators due to its long length and the ultra low emittance required. There are several techniques for measuring the ILC reference network; in this…

Instrumentation and Detectors · Physics 2009-02-02 John Dale , Armin Reichold

Background and purpose: To propose a novel machine learning-based method for reliable and accurate modeling of linac beam data applicable to the processes of linac commissioning and QA. Materials and methods: We hypothesize that the beam…

Medical Physics · Physics 2020-10-07 Wei Zhao , Ishan Patil , Bin Han , Yong Yang , Lei Xing , Emil Schüler

In this manuscript, we investigated the accuracy of the entire chain of phase space files generated by the TrueBeam VirtuaLinac system in clinical treatment plans. Good agreement was obtained between the MC simulation and the clinical…

Medical Physics · Physics 2015-09-24 Yue Yan , Poonam Yadav , Daniel Saenz , Bhudatt R. Paliwal

General description of an on-line procedure of calibration for IGRT (Image Guided Radiotherapy) is given. The algorithm allows to improve targeting cancer by estimating its position in space and suggests appropriate correction of the…

Medical Physics · Physics 2019-04-02 R. A. Kycia , Z. Tabor , A. Woszczyna , D. Kabat , M. Tulik , Z. Latała

Purpose: The XCAT phantom allows for highly sophisticated multimodality imaging research. It includes a complete set of organs, muscle, bone, soft tissue, while also accounting for age, sex, and body mass index (BMI), which allows phantom…

A central tracker based on silicon microstrip sensors has been envisaged for the e+e- linear collider experiments. A full simulation program based on GEANT4 has been developed to study performance of the tracker. We report some preliminary…

High Energy Physics - Experiment · Physics 2007-05-23 M. Iwasaki

The Fast Dose Calculator (FDC), a track repeating algorithm Monte Carlo method was initially developed for proton therapy. The validation for proton therapy has been demonstrated in a previous work. This method can be expanded to ion…

Medical Physics · Physics 2018-09-18 Qianxia Wang , Antony Adair , Yu Deng , Hongliang Chen , M Moyers , James Lin , Pablo Yepes

A macroscopic reconstruction is developed to infer iRPC performance using Geant4 observables and one experimental anchor. The Geant4 energy deposition is used to estimate the primary ionization yield, while the efficiency turn-on is modeled…

Instrumentation and Detectors · Physics 2025-12-17 V. O. Ramirez-Beltran , Cecilia Uribe Estrada , Mauricio Flores Geronimo , François Lagarde

Here, we introduce Linac_Gen, a tool developed at Fermilab, which combines machine learning algorithms with Particle-in-Cell methods to advance beam dynamics in linacs. Linac_Gen employs techniques such as Random Forest, Genetic Algorithms,…

Accelerator Physics · Physics 2024-06-25 Abhishek Pathak

The simulation of the instruments based on the cascade multiplication of electrons has always been an important and challenging subject in no matter high energy physics, astrophysics, radiography and other fields. In this work, a generic…

Instrumentation and Detectors · Physics 2023-10-10 Han Miao , Huaxing Peng , Baojun Yan , Shulin Liu , Hai-Bo Li

Current Total Skin Electron Therapy (TSET) Stanford technique for cutaneous lymphoma, established in the 70's, involves a unique irradiation setup, i.e. patient's position and beam arrangement, for all patients with ensuing great…

This study investigates the sensitivity and specificity of the MapCHECK phantom housed in MapPHAN to errors in conformal arc Stereotactic Ablative Body Radiotherapy (SABR). A specific focus is applied to Organ At Risk (OAR) dosimetry.…

Medical Physics · Physics 2025-08-22 Nathan I. N. Henry , Christopher M. Thompson , Steven Marsh , Jack D. Aylward

Patient-derived cells (PDC) mouse xenografts are increasingly important tools in glioblastoma (GBM) research, essential to investigate case-specific growth patterns and treatment responses. Despite the central role of xenograft models in…

Quantitative Methods · Quantitative Biology 2024-03-15 Adam A. Malik , Cecilia Krona , Soumi Kundu , Philip Gerlee , Sven Nelander

Radiation detection is vital for space, medical imaging, homeland security, and environmental monitoring applications. In the past, the Monte Carlo radiation transport toolkit, Geant4, has been employed to enable the effective development…

Instrumentation and Detectors · Physics 2024-10-14 Lysander Miller , Airlie Chapman , Katie Auchettl , Jeremy M. C. Brown
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