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The discovery of synthetically accessible organic semiconductors with exceptional performance remains a critical bottleneck in materials science. While these materials offer compelling advantages - structural modularity, mechanical…

Enzyme Commission (EC) numbers, which associate a protein sequence with the biochemical reactions it catalyzes, are essential for the accurate understanding of enzyme functions and cellular metabolism. Many ab-initio computational…

Machine Learning · Computer Science 2023-06-07 Zhenkun Shi , Qianqian Yuan , Ruoyu Wang , Hoaran Li , Xiaoping Liao , Hongwu Ma

High throughput real-time instruments are needed to acquire large data sets for detection and classification of rare events. Enabled by the photonic time stretch digitizer, a new class of instruments with record throughputs have led to the…

Optics · Physics 2015-03-20 Bahram Jalali , Ata Mahjoubfar , Claire L. Chen

Nanopore protein sequencing produces long, noisy ionic current traces in which key molecular phases, such as protein capture and translocation, are embedded. Capture phases mark the successful entry of a protein into the pore and serve as…

Machine Learning · Computer Science 2025-11-04 Annabelle Martin , Daphne Kontogiorgos-Heintz , Jeff Nivala

High-harmonic spectroscopy (HHS) is a nonlinear all-optical technique with inherent attosecond temporal resolution, which has been applied successfully to a broad variety of systems in the gas phase and solid state. Here, we extend HHS to…

Convolutional Neural Networks (CNNs) continue to achieve great success in classification tasks as innovative techniques and complex multi-path architecture topologies are introduced. Neural Architecture Search (NAS) aims to automate the…

Neural and Evolutionary Computing · Computer Science 2023-12-14 Trevor Londt , Xiaoying Gao , Peter Andreae , Yi Mei

HEP-Frame is a new C++ package designed to efficiently perform analyses of data sets from a very large number of events, like those available at the Large Hadron Collider (LHC) at CERN, Geneva. It mainly targets high performance servers and…

High Energy Physics - Experiment · Physics 2023-03-10 A. Pereira , A. Onofre , A. Proenca

Digital PCR (dPCR) has revolutionized nucleic acid diagnostics by enabling absolute quantification of rare mutations and target sequences. However, current detection methodologies face challenges, as flow cytometers are costly and complex,…

Quantitative Methods · Quantitative Biology 2024-03-29 Yuanyuan Wei , Shanhang Luo , Changran Xu , Yingqi Fu , Qingyue Dong , Yi Zhang , Fuyang Qu , Guangyao Cheng , Yi-Ping Ho , Ho-Pui Ho , Wu Yuan

Coherent elastic neutrino-nucleus scattering (CE$\nu$NS) stands out as a pivotal process for precision tests of the Standard Model electroweak sector, investigations of neutrino properties, and searches for new physics (NP). Recent…

High Energy Physics - Phenomenology · Physics 2026-01-28 Gang Li , Chuan-Qiang Song , Feng-Jie Tang , Jiang-Hao Yu

Physicians perform minimally invasive percutaneous procedures under Computed Tomography (CT) image guidance both for the diagnosis and treatment of numerous diseases. For these procedures performed within Computed Tomography Scanners,…

Computer vision technology is widely used in biological and medical data analysis and understanding. However, there are still two major bottlenecks in the field of cell membrane segmentation, which seriously hinder further research: lack of…

Computer Vision and Pattern Recognition · Computer Science 2020-10-19 Ruohua Shi , Wenyao Wang , Zhixuan Li , Liuyuan He , Kaiwen Sheng , Lei Ma , Kai Du , Tingting Jiang , Tiejun Huang

Image registration is a fundamental requirement for medical image analysis. Deep registration methods based on deep learning have been widely recognized for their capabilities to perform fast end-to-end registration. Many deep registration…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Mingyuan Meng , Lei Bi , Michael Fulham , Dagan Feng , Jinman Kim

Using smart wearable devices to monitor patients electrocardiogram (ECG) for real-time detection of arrhythmias can significantly improve healthcare outcomes. Convolutional neural network (CNN) based deep learning has been used successfully…

Machine Learning · Computer Science 2021-09-07 Xiaolin Li , Rajesh Panicker , Barry Cardiff , Deepu John

The recent detection of coherent elastic neutrino-nucleus scattering (CE$\nu$NS) opens the possibility to use neutrinos to explore physics beyond standard model, with small-size detectors. However, the CE$\nu$NS process generates signals at…

High Energy Physics - Experiment · Physics 2024-01-10 A. Simón

Human activity recognition (HAR) research often lacks accessible, comprehensive field data. Commercial systems are rarely open source, hard to expand, and limited by issues like node synchronisation, data throughput, unclear sensor…

Networking and Internet Architecture · Computer Science 2025-07-28 Philipp Lepold , Tobias Röddiger , Michael Beigl

The ALICE (A Large Ion Collider Experiment) detector yields a huge sample of data from different sub-detectors. On-line data processing is applied to select and reduce the volume of the stored data. ALICE applies a multi-level hardware…

Instrumentation and Detectors · Physics 2019-08-14 F. Ronchetti , F. Blanco , M. Figueredo , A. G. Knospe , L. Xaplanteris

Nuclei segmentation is a fundamental task in digital pathology analysis and can be automated by deep learning-based methods. However, the development of such an automated method requires a large amount of data with precisely annotated masks…

Computer Vision and Pattern Recognition · Computer Science 2021-11-25 Jiangbo Shi , Chang Jia , Zeyu Gao , Tieliang Gong , Chunbao Wang , Chen Li

Fully Homomorphic Encryption (FHE) relies heavily on the Number Theoretic Transform (NTT), making NTT a major performance bottleneck due to its intensive polynomial computations. Hybrid Homomorphic Encryption (HHE), which integrates…

Hardware Architecture · Computer Science 2026-03-03 Hang Gu , Teng Wang , Qianyu Cheng , Jinao Li , Zhendong Zheng , Lei Gong , Wenqi Lou , Xi Li , Xuehai Zhou

Rare semantic innovations in high-dimensional, mission-critical domains are often obscured by dense background contexts, a challenge we define as \textit{feature density conflict}. We introduce the \textbf{Hybrid Hierarchical SAE (HH-SAE)}…

Machine Learning · Computer Science 2026-05-12 Honghan Wu , Tianyan Wang , Jiacong Mi , Zhoyang Jiang , Yunsoo Kim

Computational analysis methods including machine learning have a significant impact in the fields of genomics and medicine. High-throughput gene expression analysis methods such as microarray technology and RNA sequencing produce enormous…

Genomics · Quantitative Biology 2022-09-28 Nikita Bhandari , Rahee Walambe , Ketan Kotecha , Satyajeet Khare