Related papers: Towards a New Spatial Representation of Bone Remod…
Living biological tissue is a complex system, constantly growing and changing in response to external and internal stimuli. These processes lead to remarkable and intricate changes in shape. Modeling and understanding both natural and…
Neurological injuries and age-related decline can impair sensory processing and disrupt motor coordination, gait, and balance. As mechanisms of neuroplasticity have become better understood, vibration-based interventions have gained…
Integral-type nonlocal damage models describe the fracture process zones by regular strain profiles insensitive to the size of finite elements, which is achieved by incorporating weighted spatial averages of certain state variables into the…
Many bone shapes in the human skeleton are characterized by profiles that can be associated to equations of algebraic curves. Fixing the parameters in the curve equation, by means of a classical pattern recognition procedure like the Hough…
Large-scale perturbations in the microbiome constitution are strongly correlated, whether as a driver or a consequence, with the health and functioning of human physiology. However, understanding the difference in the microbiome profiles of…
Neurodegenerative diseases are characterized by the accumulation of misfolded proteins and widespread disruptions in brain function. Computational modeling has advanced our understanding of these processes, but efforts have traditionally…
At elevated temperature environments, elastic structures experience a change of the stress-free state of the body that can strongly influence the optimal topology of the structure. This work presents level-set based topology optimization of…
Surface growth, i.e., the addition or removal of mass from the boundary of a solid body, occurs in a wide range of processes, including the growth of biological tissues, solidification and melting, and additive manufacturing. To understand…
Analyzing and inspecting bone marrow cell cytomorphology is a critical but highly complex and time-consuming component of hematopathology diagnosis. Recent advancements in artificial intelligence have paved the way for the application of…
A significant and rising proportion of the global population suffer from non-communicable diseases, such as neurological disorders. Neurorehabilitation aims to restore function and independence of neurological patients through providing…
Partitionings (or segmentations) divide a given domain into disjoint connected regions whose union forms again the entire domain. Multi-dimensional partitionings occur, for example, when analyzing parameter spaces of simulation models,…
Membrane computing is a well-established and successful research field which belongs to the more general area of molecular computing. Membrane computing aims at defining parallel and non-deterministic computing models, called membrane…
The advent of high resolution imaging has made data on surface shape widespread. Methods for the analysis of shape based on landmarks are well established but high resolution data require a functional approach. The starting point is a…
A distinguishing feature of a multicellular living system is that it operates at various scales, from the intracellular to organismal. Very little is known at present on how tissue level properties are related to cell and subcellular…
Humans naturally possess the spatial reasoning ability to form and manipulate images and structures of objects in space. There is an increasing effort to endow Vision-Language Models (VLMs) with similar spatial reasoning capabilities.…
In this study, we investigated a method allowing the determination of the femur bone surface as well as its mechanical axis from some easy-to-identify bony landmarks. The reconstruction of the whole femur is therefore performed from these…
When considering sparse motion capture marker data, one typically struggles to balance its overfitting via a high dimensional blendshape system versus underfitting caused by smoothness constraints. With the current trend towards using more…
Morphogenesis, the process by which an adult organism emerges from a single cell, has fascinated humans for a long time. Modelling this process can provide novel insights into development and the principles that orchestrate the…
The medial axis transform is a well-known tool for shape recognition. Instead of the object contour, it equivalently describes a binary object in terms of a skeleton containing all centres of maximal inscribed discs. While this shape…
The human neuromuscular system consisting of skeletal muscles and neural circuits is a complex system that is not yet fully understood. Surface electromyography (EMG) can be used to study muscle behavior from the outside. Computer…