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Maximum Entropy is a powerful concept that entails a sharp separation between relevant and irrelevant variables. It is typically invoked in inference, once an assumption is made on what the relevant variables are, in order to estimate a…

Statistical Mechanics · Physics 2018-01-09 Luigi Gresele , Matteo Marsili

The problem of interaction selection has recently caught much attention in high dimensional data analysis. This note aims to address and clarify several fundamental issues in interaction selection for linear regression models, especially…

Methodology · Statistics 2015-10-08 Ning Hao , Hao Helen Zhang

Recent work has shown great promise in explaining neural network behavior. In particular, feature attribution methods explain which features were most important to a model's prediction on a given input. However, for many tasks, simply…

Machine Learning · Computer Science 2020-07-01 Joseph D. Janizek , Pascal Sturmfels , Su-In Lee

This paper studies inference in linear models with a high-dimensional parameter matrix that can be well-approximated by a ``spiked low-rank matrix.'' A spiked low-rank matrix has rank that grows slowly compared to its dimensions and nonzero…

Statistics Theory · Mathematics 2023-01-04 Victor Chernozhukov , Christian Hansen , Yuan Liao , Yinchu Zhu

Associative memory models are content-addressable memory systems fundamental to biological intelligence and are notable for their high interpretability. However, existing models evaluate the quality of retrieval based on proximity, which…

Machine Learning · Computer Science 2025-11-26 Shurong Wang , Yuqi Pan , Zhuoyang Shen , Meng Zhang , Hongwei Wang , Guoqi Li

High-dimensional statistical inference with general estimating equations are challenging and remain less explored. In this paper, we study two problems in the area: confidence set estimation for multiple components of the model parameters,…

Methodology · Statistics 2021-04-28 Jinyuan Chang , Song Xi Chen , Cheng Yong Tang , Tong Tong Wu

Recent work has shown that probabilistic models based on pairwise interactions-in the simplest case, the Ising model-provide surprisingly accurate descriptions of experiments on real biological networks ranging from neurons to genes.…

Quantitative Methods · Quantitative Biology 2007-12-18 Tamara Broderick , Miroslav Dudik , Gasper Tkacik , Robert E. Schapire , William Bialek

Many systems exhibit complex interactions between their components: some features or actions amplify each other's effects, others provide redundant information, and some contribute independently. We present a simple geometric method for…

Machine Learning · Computer Science 2025-12-15 Ahmad Shamail , Claire McWhite

To model modern large-scale datasets, we need efficient algorithms to infer a set of $P$ unknown model parameters from $N$ noisy measurements. What are fundamental limits on the accuracy of parameter inference, given finite signal-to-noise…

Machine Learning · Statistics 2016-09-07 Madhu Advani , Surya Ganguli

In this work we approach attractor neural networks from a machine learning perspective: we look for optimal network parameters by applying a gradient descent over a regularized loss function. Within this framework, the optimal…

Machine Learning · Computer Science 2024-02-21 Elena Agliari , Francesco Alemanno , Miriam Aquaro , Alberto Fachechi

Hypergraphs, encoding structured interactions among any number of system units, have recently proven a successful tool to describe many real-world biological and social networks. Here we propose a framework based on statistical inference to…

Social and Information Networks · Computer Science 2022-12-01 Martina Contisciani , Federico Battiston , Caterina De Bacco

Systems of interacting continuous-time Markov chains are a powerful model class, but inference is typically intractable in high dimensional settings. Auxiliary information, such as noisy observations, is typically only available at discrete…

Machine Learning · Statistics 2026-04-21 Giosue Migliorini , Padhraic Smyth

Growing demand for high-speed Ising-computing-specific hardware has prompted a need for determining how the accuracy depends on a hardware implementation with physically limited resources. For instance, in digital hardware such as…

Statistical Mechanics · Physics 2021-10-07 Ryuta Sasaki , Toru Aonishi

Correlations between two variables of a high-dimensional system can be indicative of an underlying interaction, but can also result from indirect effects. Inverse Ising inference is a method to distinguish one from the other. Essentially,…

Populations and Evolution · Quantitative Biology 2014-12-10 Benedikt Obermayer , Erel Levine

In statistical learning framework with regressions, interactions are the contributions to the response variable from the products of the explanatory variables. In high-dimensional problems, detecting interactions is challenging due to…

Methodology · Statistics 2019-10-01 Cheng Yong Tang , Ethan X. Fang , Yuexiao Dong

We give an approximate solution to the difficult inverse problem of inferring the topology of an unknown network from given time-dependent signals at the nodes. For example, we measure signals from individual neurons in the brain, and infer…

Biological Physics · Physics 2021-01-27 Corey Weistuch , Luca Agozzino , Lilianne R. Mujica-Parodi , Ken A. Dill

Advanced inference techniques allow one to reconstruct the pattern of interaction from high dimensional data sets. We focus here on the statistical properties of inferred models and argue that inference procedures are likely to yield models…

Data Analysis, Statistics and Probability · Physics 2013-10-09 Iacopo Mastromatteo , Matteo Marsili

Predicting user influence in social networks is a critical problem, and hypergraphs, as a prevalent higher-order modeling approach, provide new perspectives for this task. However, the absence of explicit cascade or infection probability…

Social and Information Networks · Computer Science 2025-08-22 Su-Su Zhang , JinFeng Xie , Yang Chen , Min Gao , Cong Li , Chuang Liu , Xiu-Xiu Zhan

Our recent paper [Grauwin et al. Sci. Rep. 7 (2017)] demonstrates that community and hierarchical structure of the networks of human interactions largely determines the least and should be taken into account while modeling them. In the…

Social and Information Networks · Computer Science 2017-12-18 Stanislav Sobolevsky

Ising models describe the joint probability distribution of a vector of binary feature variables. Typically, not all the variables interact with each other and one is interested in learning the presumably sparse network structure of the…

Machine Learning · Computer Science 2019-07-09 Frank Nussbaum , Joachim Giesen