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Patterns that appear rarely or unusually in the data can be defined as outlier patterns. The basic idea behind detecting outlier patterns is comparison of their relative frequencies with frequent patterns. Their frequencies of appearance…

Databases · Computer Science 2015-07-08 Archana N. , S. S. Pawar

We study the effects of the sequence on the propagation of nonlinear excitations in simple models of DNA, and how those effects are modified by noise. Starting from previous results on soliton dynamics on lattices defined by aperiodic…

Biomolecules · Quantitative Biology 2009-11-10 Sara Cuenda , Angel Sanchez

Biological cells replicate their genomes in a well-planned manner. The DNA replication program of an organism determines the timing at which different genomic regions are replicated, with fundamental consequences for cell homeostasis and…

Subcellular Processes · Quantitative Biology 2024-05-28 Florian Pflug , Deepak Bhat , Simone Pigolotti

We analyze the spectral distribution of symmetric random matrices with correlated entries. While we assume that the diagonals of these random matrices are stochastically independent, the elements of the diagonals are taken to be correlated.…

Probability · Mathematics 2012-05-31 Olga Friesen , Matthias Löwe

The spectra of random feature matrices provide essential information on the conditioning of the linear system used in random feature regression problems and are thus connected to the consistency and generalization of random feature models.…

Machine Learning · Statistics 2022-12-13 Zhijun Chen , Hayden Schaeffer , Rachel Ward

The mitotic cell cycle governs DNA replication and cell division. The effectiveness of radiotherapy and chemotherapy depends on cell-cycle position, with increased resistance during DNA replication and mitosis. Thus, accurate mathematical…

Cell Behavior · Quantitative Biology 2026-03-10 Ruby E. Nixson , Helen M. Byrne , Joe M. Pitt-Francis , Philip K. Maini

It is basic question in biology and other fields to identify the char- acteristic properties that on one hand are shared by structures from a particular realm, like gene regulation, protein-protein interaction or neu- ral networks or…

Quantitative Methods · Quantitative Biology 2012-10-19 Anirban Banerjee , Jürgen Jost

Subdivision schemes are iterative methods for the design of smooth curves and surfaces. Any linear subdivision scheme can be identified by a sequence of Laurent polynomials, also called subdivision symbols, which describe the linear rules…

Numerical Analysis · Mathematics 2014-11-14 Costanza Conti , Luca Gemignani , Lucia Romani

The aim of this article is to establish asymptotic distributions and consistency of subsampling for spectral density and for magnitude of coherence for non-stationary, almost periodically correlated time series. We show the asymptotic…

Statistics Theory · Mathematics 2011-02-11 Łukasz Lenart

Interpretable classification of time series presents significant challenges in high dimensions. Traditional feature selection methods in the frequency domain often assume sparsity in spectral density matrices (SDMs) or their inverses, which…

Machine Learning · Statistics 2024-08-19 Sarbojit Roy , Malik Shahid Sultan , Hernando Ombao

In recent work, we considered the frequencies of patterns of consecutive primes $\pmod{q}$ and numerically found biases toward certain patterns and against others. We made a conjecture explaining these biases, the dominant factor in which…

Number Theory · Mathematics 2017-09-20 Robert J. Lemke Oliver , Kannan Soundararajan

Using a nonperturbative approach we examine the large frequency asymptotics of the two-point level density correlator in weakly disordered metallic grains. This allows us to study the behavior of the two-level structure factor close to the…

Condensed Matter · Physics 2016-08-31 A. V. Andreev , B. L. Altshuler

The spectral fluctuations of complex quantum systems, in appropriate limit, are known to be consistent with that obtained from random matrices. However, this relation between the spectral fluctuations of physical systems and random matrices…

Quantum Physics · Physics 2020-09-16 S. Harshini Tekur , M. S. Santhanam

In this paper, we develop a structure theory for generalized spectral sequences, which are derived from chain complexes that are filtered over arbitrary partially ordered sets. Also, a more general construction method reminiscent of exact…

Algebraic Topology · Mathematics 2022-03-21 Benjamin Matschke

Deep generative models for anomaly detection in multivariate time-series are typically trained by maximizing data likelihood. However, likelihood in observation space measures marginal density rather than conformity to structured temporal…

Artificial Intelligence · Computer Science 2026-03-13 David Baumgartner , Eliezer de Souza da Silva , Iñigo Urteaga

A three-dimensional model of the genetic vocabulary is proposed in terms of determinative degree, an introduced characteristic of nucleotide, which reflects absolute difference between purin and pyrimidin bases in one DNA strand. In the…

Chemical Physics · Physics 2007-05-23 Diana Duplij , Steven Duplij

In this paper we treat some fractal and statistical features of the DNA sequences. First, a fractal record model of DNA sequence is proposed by mapping DNA sequences to integer sequences, followed by R/S analysis of the model and…

Biological Physics · Physics 2018-01-17 Zu-Guo Yu , Guo-Yi Chen

Tools that effectively analyze and compare sequences are of great importance in various areas of applied computational research, especially in the framework of molecular biology. In the present paper, we introduce simple geometric criteria…

Quantitative Methods · Quantitative Biology 2013-08-14 Boris Brimkov , Valentin E. Brimkov

Important aspects of the process of information storage and retrieval in DNA and RNA, and its evolution, are the role of the anticodons and associated $t$RNA's, and correlations between anticodons and amino acids; the degeneracy of the…

Biological Physics · Physics 2007-05-23 P. D. Jarvis , J. D. Bashford

Genomic phenotypes, such as DNA methylation and chromatin accessibility, can be used to characterize the transcriptional and regulatory activity of DNA within a cell. Recent technological advances have made it possible to measure such…

Methodology · Statistics 2016-11-15 Jean Morrison , Noah Simon , Daniela Witten