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The human brain has been studied at multiple scales, from neurons, circuits, areas with well defined anatomical and functional boundaries, to large-scale functional networks which mediate coherent cognition. In a recent work, we addressed…

Biological Physics · Physics 2012-05-17 Lazaros K. Gallos , Mariano Sigman , Hernan A. Makse

Many fMRI analyses examine functional connectivity, or statistical dependencies among remote brain regions. Yet popular methods for studying whole-brain functional connectivity often yield results that are difficult to interpret. Factor…

Methodology · Statistics 2024-09-24 Kyle Stanley , Nicole Lazar , Matthew Reimherr

With the advances in high resolution neuroimaging, there has been a growing interest in the detection of functional brain connectivity. Complex network theory has been proposed as an attractive mathematical representation of functional…

Neural and Evolutionary Computing · Computer Science 2018-09-18 Arash Golibagh Mahyari , Selin Aviyente

Large-scale white matter pathways crisscrossing the cortex create a complex pattern of connectivity that underlies human cognitive function. Generative mechanisms for this architecture have been difficult to identify in part because little…

Neurons and Cognition · Quantitative Biology 2015-06-16 Florian Klimm , Danielle S. Bassett , Jean M. Carlson , Peter J. Mucha

Comparing weighted networks in neuroscience is hard, because the topological properties of a given network are necessarily dependent on the number of edges of that network. This problem arises in the analysis of both weighted and unweighted…

Applications · Statistics 2014-03-28 Cedric E. Ginestet , Arnaud P. Fournel , Andrew Simmons

Functional MRI is a neuroimaging technique that analyzes the functional activity of the brain by measuring blood-oxygen-level-dependent signals throughout the brain. The derived functional features can be used for investigating brain…

Neurons and Cognition · Quantitative Biology 2026-02-16 Giorgio Dolci , Silvia Saglia , Lorenza Brusini , Vince D. Calhoun , Ilaria Boscolo Galazzo , Gloria Menegaz

The rapid evolution of network services demands new paradigms for studying and designing networks. In order to understand the underlying mechanisms that provide network functions, we propose a framework which enables the functional analysis…

Social and Information Networks · Computer Science 2017-10-09 Merim Dzaferagic , Nicholas Kaminski , Neal McBride , Irene Macaluso , Nicola Marchetti

Complex networks are a powerful modeling tool, allowing the study of countless real-world systems. They have been used in very different domains such as computer science, biology, sociology, management, etc. Authors have been trying to…

Social and Information Networks · Computer Science 2014-02-04 Burcu Kantarcı , Vincent Labatut

Brain Functional Networks (BFNs), graph theoretical models of brain activity data, provide a systems perspective of complex functional connectivity within the brain. Neurological disorders are known to have basis in abnormal functional…

Quantitative Methods · Quantitative Biology 2016-08-30 Megha Singh , Rahul Badhwar , Ganesh Bagler

Quantitative descriptions of network structure in big data can provide fundamental insights into the function of interconnected complex systems. Small-world structure, commonly diagnosed by high local clustering yet short average path…

Neurons and Cognition · Quantitative Biology 2015-05-12 Sarah Feldt Muldoon , Eric W. Bridgeford , Danielle S. Bassett

Modularity is an important topological attribute for functional brain networks. Recent studies have reported that modularity of functional networks varies not only across individuals being related to demographics and cognitive performance,…

Neurons and Cognition · Quantitative Biology 2018-10-05 Makoto Fukushima , Richard F. Betzel , Ye He , Marcel A. de Reus , Martijn P. van den Heuvel , Xi-Nian Zuo , Olaf Sporns

Modeling the behavior of coupled networks is challenging due to their intricate dynamics. For example in neuroscience, it is of critical importance to understand the relationship between the functional neural processes and anatomical…

Machine Learning · Computer Science 2021-04-20 Hongyuan You , Sikun Lin , Ambuj K. Singh

We review the main tools which allow for the statistical characterization of weighted networks. We then present two case studies, the airline connection network and the scientific collaboration network, which are representative of critical…

Statistical Mechanics · Physics 2009-11-10 Marc Barthelemy , Alain Barrat , Romualdo Pastor-Satorras , Alessandro Vespignani

We study functional activity in the human brain using functional Magnetic Resonance Imaging and recently developed tools from network science. The data arise from the performance of a simple behavioural motor learning task. Unsupervised…

Anatomical connectivity between different regions in the brain can be mapped to a network representation, the connectome, where the intensities of the links, the weights, influence its structural resilience and the functional processes it…

Neurons and Cognition · Quantitative Biology 2025-04-09 Laia Barjuan , Muhua Zheng , M. Ángeles Serrano

If brain anatomy and dynamics have a genuine complex network structure as it has become standard to posit, it is also reasonable to assume that such a structure should play a key role not only in brain function but also in brain…

Neurons and Cognition · Quantitative Biology 2025-08-01 David Papo , Javier M. Buldú

Functional connectomes capture brain interactions via synchronized fluctuations in the functional magnetic resonance imaging signal. If measured during rest, they map the intrinsic functional architecture of the brain. With task-driven…

Neurons and Cognition · Quantitative Biology 2013-04-16 Gaël Varoquaux , R. C. Craddock

Graph-theoretical analyses of complex brain networks is a rapidly evolving field with a strong impact for neuroscientific and related clinical research. Due to a number of confounding variables, however, a reliable and meaningful…

Neurons and Cognition · Quantitative Biology 2014-08-27 Gerrit Ansmann , Klaus Lehnertz

Many real-world complex networks exhibit a community structure, in which the modules correspond to actual functional units. Identifying these communities is a key challenge for scientists. A common approach is to search for the network…

Physics and Society · Physics 2016-12-22 Federico Botta , Charo I. del Genio

A good deal of current research in complex networks involves the characterization and/or classification of the topological properties of given structures, which has motivated several respective measurements. This letter proposes a framework…

Physics and Society · Physics 2016-07-26 Cesar H. Comin , Filipi N. Silva , Luciano da F. Costa