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Social distancing strategies have been adopted by governments to manage the COVID-19 pandemic, since the first outbreak began. However, further epidemic waves keep out the return of economic and social activities to their standard levels of…

Optimization and Control · Mathematics 2021-06-07 J. E. Sereno , A. D' Jorge , A. Ferramosca , E. A. Hernandez-Vargas , A. H. Gonzalez

We consider the low-prevalence linearized SEIR epidemic model for a society that has resolved to keep future infections low in anticipation of a vaccine. The society can vary its amount of potentially-infection-spreading activity over time,…

Optimization and Control · Mathematics 2020-09-17 Scott Sheffield

In this paper we consider SIR epidemics on random graphs with clustering. To incorporate group structure of the underlying social network, we use a generalized version of the configuration model in which each node is a member of a specified…

Probability · Mathematics 2018-02-15 Carolina Fransson , Pieter Trapman

We consider the interplay of vaccination and migration rates on disease persistence in epidemiological systems. We show that short-term and long-term migration can inhibit disease persistence. As a result, we show how migration changes how…

Biological Physics · Physics 2012-05-22 Jackson Burton , Lora Billings , Derek A. T. Cummings , Ira B. Schwartz

This paper is a survey paper on stochastic epidemic models. A simple stochastic epidemic model is defined and exact and asymptotic model properties (relying on a large community) are presented. The purpose of modelling is illustrated by…

Probability · Mathematics 2009-11-05 Tom Britton

A generalization of the standard susceptible-infectious-removed (SIR) stochastic model for epidemics in sparse random networks is introduced which incorporates contact tracing in addition to random screening. We propose a deterministic…

Adaptation and Self-Organizing Systems · Physics 2009-11-07 Ramon Huerta , Lev S. Tsimring

We propose an epidemic model for the spread of vector-borne diseases. The model, which is built extending the classical susceptible-infected-susceptible model, accounts for two populations -- humans and vectors -- and for cross-contagion…

Systems and Control · Electrical Eng. & Systems 2025-10-21 Lorenzo Zino , Alessandro Casu , Alessandro Rizzo

In this work we analyze mathematically the consequences and effectiveness of strategies to control an epidemic in the framework of classical SEIR models with multiple parallel infectious stages. We define the mathematical concept of a…

Dynamical Systems · Mathematics 2023-08-17 Annibal Figueiredo , Tarcısio Marciano da Rocha Filho

The goal of this work is to consider widespread use of face masks as a non-pharmaceutical control strategy for the Covid-19 pandemic. A SEIR model that divides the population into individuals that wear masks and those that do not is…

Populations and Evolution · Quantitative Biology 2021-02-03 João A. M. Gondim

We study vaccine control for disease spread on an adaptive network modeling disease avoidance behavior. Control is implemented by adding Poisson distributed vaccination of susceptibles. We show that vaccine control is much more effective in…

Populations and Evolution · Quantitative Biology 2015-05-13 Leah B. Shaw , Ira B. Schwartz

Motivated by the increasing number of COVID-19 cases that have been observed in many countries after the vaccination and relaxation of non-pharmaceutical interventions, we propose a mathematical model on time-varying networks for the spread…

Dynamical Systems · Mathematics 2022-03-09 Kathinka Frieswijk , Lorenzo Zino , Ming Cao

This paper studies an optimal control problem for a class of SIR epidemic models, in scenarios in which the infected population is constrained to be lower than a critical threshold imposed by the ICU (intensive care unit) capacity. The…

Optimization and Control · Mathematics 2024-12-31 Matteo Della Rossa , Lorenzo Freddi , Dan Goreac

This is an epidemiological SIRV model based study that is designed to analyze the impact of vaccination in containing infection spread, in a 4-tiered population compartment comprised of susceptible, infected, recovered and vaccinated…

Populations and Evolution · Quantitative Biology 2018-11-14 Ewa Grela , Michael Stich , Amit K Chattopadhyay

We introduce a multi-layer networked compartmental $SIRS-V_o$ model that captures opinion dynamics, disease spread, risk perception, and self-interest vaccine-uptake behavior in an epidemic process. We characterize the target vaccination…

Physics and Society · Physics 2023-04-26 Humphrey Leung , Zhuocong Li , Baike She , Philip E. Paré

We consider the problem of controlling the propagation of an epidemic outbreak in an arbitrary contact network by distributing vaccination resources throughout the network. We analyze a networked version of the…

Social and Information Networks · Computer Science 2013-03-19 Victor M. Preciado , Michael Zargham , Chinwendu Enyioha , Ali Jadbabaie , George Pappas

The outbreak of mutant strains and vaccination behaviors have been the focus of recent epidemiological research, but most existing epidemic models failed to simultaneously capture viral mutation and consider the complexity and behavioral…

Populations and Evolution · Quantitative Biology 2026-01-16 Wenjie Zhang , Yusheng Li , Qin Li , Guojun Huang , Minyu Feng

In this study, we present an epidemic-controlled SIRD model with two types of control strategies: mask wear and screening. The aim of this study is to minimize the number of deceased keeping a minimal cost of mask advertising and screening.…

Populations and Evolution · Quantitative Biology 2021-09-06 Amira Bouhali , Walid Ben Aribi , Slimane Ben Miled , Amira Kebir

In the framework of homogeneous susceptible-infected-recovered (SIR) models, we use a control theory approach to identify optimal pandemic mitigation strategies. We derive rather general conditions for reaching herd immunity while…

Populations and Evolution · Quantitative Biology 2021-07-05 Prakhar Godara , Stephan Herminghaus , Knut M. Heidemann

This article considers the optimal control of the SIR model with both transmission and treatment uncertainty. It follows the model presented in Gatto and Schellhorn (2021). We make four significant improvements on the latter paper. First,…

Optimization and Control · Mathematics 2021-05-20 Yujia Ding , Henry Schellhorn

SIRS epidemic models assume that individual immunity (from infection and vaccination) wanes in one big leap, from complete immunity to complete susceptibility. For many diseases immunity on the contrary wanes gradually, something that's…

Populations and Evolution · Quantitative Biology 2022-11-17 Mohamed El Khalifi , Tom Britton