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Drug delivery devices based on nanocomposite membranes containing thermoresponsive nanogels and superparamagnetic nanoparticles have been demonstrated to provide reversible, on-off drug release upon application (and removal) of an…

We report on novel ferrogels derived from polysaccharides (sodium alginate and chitosan) with embedded iron oxide nanoparticles synthesized in situ and their combination with thermally responsive poly (N-isopropylacrylamide) for…

Materials Science · Physics 2011-05-03 R. Hernandez , J. Sacristan , L. Asin , T. E. Torres , M. R. Ibarra , G. F. Goya , C. Mijangos

Hydrophobically modified magnetic nanoparticles (MNPs) were encapsulated within the membrane of poly(trimethylene carbonate)-b-poly(L-glutamic acid) (PTMC-b-PGA) block copolymer vesicles using a nanoprecipitation process. This formulation…

On-demand controlled drug delivery is essential for the treatment of a wide range of chronic diseases. As the drug is released at the time when required, its efficacy is boosted and the side effects are minimized. However, so far, drug…

Robotics · Computer Science 2024-03-06 Yangchao Zhou , Moonkwang Jeong , Meng Zhang , Xuexin Duan , Tian Qiu

Simple and easy to implement testbeds are needed to further advance molecular communication research. To this end, this paper presents an in-vessel molecular communication testbed using magnetic nanoparticles dispersed in an aqueous…

The integration of magnetic nanoparticles within fibrillar structures represents an interesting avenue for the remotely controlled release of therapeutic agents. This work presents a novel drug release platform based on electrospun magnetic…

Programmable materials are desirable for a variety of functional applications that range from biomedical devices, actuators and soft robots to adaptive surfaces and deployable structures. However, current smart materials are often designed…

One of the most important potential applications of self-propelled nano- and microdevices is targeted drug delivery. To realize this, biocompatible particles that can be guided collectively towards a target inside a patient's body are…

Soft Condensed Matter · Physics 2022-09-30 Tobias Nitschke , Joakim Stenhammar , Raphael Wittkowski

Systemic drug administration often causes off-target effects limiting the efficacy of advanced therapies. Targeted drug delivery approaches increase local drug concentrations at the diseased site while minimizing systemic drug exposure. We…

In this work, a novel electrospun conductive polymer nanocomposite made of polycaprolactone with an exohedral complex made of multiwalled carbon nanotubes and fullerene C60 was prepared and characterized. The preparation was straightforward…

Background: The development of smart nanocarriers that enable controlled drug release in response to internal and external triggers is an emerging approach for targeted therapy. This study focused on designing pH-sensitive,…

Ferrofluids are typically suspensions of magnetite nanoparticles, and behave as a homogeneous continuum. The production of nanoparticles with a narrow size distribution and the achievement of colloidal stability are important technological…

Fluid Dynamics · Physics 2017-04-04 S. Afkhami , Y. Renardy

Nanocomposites comprised of insulated magnetic single-domain particles are promising candidates for high-frequency, eddy current free, soft magnetic materials, but tend to suffer from low magnetic susceptibility ($<20$). Particle alignment…

Magnetic composite materials i.e. elastomers, polymer gels, or polymer solutions with embedded magnetic nanoparticles are useful for many technical and bio-medical applications. However, the microscopic details of the coupling mechanisms…

Soft Condensed Matter · Physics 2020-10-30 Patrick Kreissl , Christian Holm , Rudolf Weeber

Nanoparticle drug carriers play an important role in facilitating efficient targeted drug delivery, i.e., improving treatment success and reducing drug costs and side effects. However, the mobility of nanoparticle drug carriers poses a…

The ability to control by physical properties of the thermoresponsive polymer of PNIPAM by magnetocaloric effect was demonstrated by in-situ experiments on PNIPAM/FeRh smart composite. The concept of drug release loaded in smart composite…

Assemblies of magnetic nanoparticles show a great potential for application in biomedicine, in particular, in magnetic hyperthermia. However, to achieve desired therapeutic effect in magnetic hyperthermia the assembly of nanoparticles…

Mesoscale and Nanoscale Physics · Physics 2019-02-07 N. A. Usov

A computational method for magnetically guided drug delivery is presented and the results are compared for the aggregation process of magnetic particles within a fluid environment. The model is developed for the simulation of the…

Soft Condensed Matter · Physics 2015-04-15 N. K. Lampropoulos , E. G. Karvelas , I. E. Sarris

Generating spintronic devices has been a goal for the nano-science. We have used density function theory to determine magnetic phases of single layer and bilayer lithium doped graphene nanoflakes. We have introduced graphene flakes as…

Mesoscale and Nanoscale Physics · Physics 2016-02-03 Narjes Kheirabadi

Micro/nano-scale propulsion has attracted considerable recent attention due to its promise for biomedical applications such as targeted drug delivery. In this paper, we report on a new experimental design and theoretical modelling of…

Fluid Dynamics · Physics 2011-09-09 On Shun Pak , Wei Gao , Joseph Wang , Eric Lauga
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