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We consider a stochastic individual-based model in continuous time to describe a size-structured population for cell divisions. This model is motivated by the detection of cellular aging in biology. We address here the problem of…

Statistics Theory · Mathematics 2020-09-28 Van Ha Hoang , Thanh Mai Pham Ngoc , Vincent Rivoirard , Viet Chi Tran

We consider a size-structured model for cell division and address the question of determining the division (birth) rate from the measured stable size distribution of the population. We formulate such question as an inverse problem for an…

Analysis of PDEs · Mathematics 2009-11-11 Benoit Perthame , Jorge P. Zubelli

We consider a size-structured model for cell division and address the question of determining the division (birth) rate from the measured stable size distribution of the population. We propose a new regularization technique based on a…

Numerical Analysis · Mathematics 2013-01-21 Marie Doumic Jauffret , Benoît Perthame , Jorge P. Zubelli

We model the growth of a cell population by a piecewise deterministic Markov branching tree. Each cell splits into two offsprings at a division rate $B(x)$ that depends on its size $x$. The size of each cell grows exponentially in time, at…

Probability · Mathematics 2015-05-29 Marie Doumic , Marc Hoffmann , Nathalie Krell , Lydia Robert

We consider a size-structured population describing the cell divisions. The cell population is described by an empirical measure and we observe the divisions in the continuous time interval [0, T ]. We address here the problem of estimating…

Statistics Theory · Mathematics 2016-05-20 Van Ha Hoang

We consider a binary branching process structured by a stochastic trait that evolves according to a diffusion process that triggers the branching events, in the spirit of Kimmel's model of cell division with parasite infection. Based on the…

Statistics Theory · Mathematics 2019-02-27 Marc Hoffmann , Aline Marguet

This paper analyzes a stochastic logistic difference equation under the assumption that the population distribution follows a normal distribution. Our focus is on the mathematical relationship between the average growth rate and a newly…

Probability · Mathematics 2025-04-22 Haiyan Wang

The multivariate hypergeometric distribution describes sampling without replacement from a discrete population of elements divided into multiple categories. Addressing a gap in the literature, we tackle the challenge of estimating discrete…

Machine Learning · Computer Science 2024-06-11 Liam Hodgson , Danilo Bzdok

Is it possible to estimate the dependence of a growing and dividing population on a given trait in the case where this trait is not directly accessible by experimental measurements, but making use of measurements of another variable? This…

Statistics Theory · Mathematics 2019-07-12 Marie Doumic , Adélaïde Olivier , Lydia Robert

Many unicellular organisms allocate their key proteins asymmetrically between the mother and daughter cells, especially in a stressed environment. A recent theoretical model is able to predict when the asymmetry in segregation of key…

Populations and Evolution · Quantitative Biology 2021-08-11 Jiseon Min , Ariel Amir

The growth-fragmentation equation arises in many different contexts, ranging from cell division, protein polymerization, biopolymers, neurosciences etc. Direct observation of temporal dynamics being often difficult, it is of main interest…

Analysis of PDEs · Mathematics 2013-01-21 Marie Doumic Jauffret , Leon M. Null Tine

We study the nonparametric estimation of the branching rate $B(x)$ of a supercritical Bellman-Harris population: a particle with age $x$ has a random lifetime governed by $B(x)$; at its death time, it gives rise to $k \geq 2$ children with…

Other Statistics · Statistics 2015-10-14 Marc Hoffmann , Adélaïde Olivier

In many statistical and econometric applications, we gather individual samples from various interconnected populations that undeniably exhibit common latent structures. Utilizing a model that incorporates these latent structures for such…

Methodology · Statistics 2023-09-19 Archer Gong Zhang , Jiahua Chen

This paper develops a threshold regression model where an unknown relationship between two variables nonparametrically determines the threshold. We allow the observations to be cross-sectionally dependent so that the model can be applied to…

Econometrics · Economics 2021-01-29 Yoonseok Lee , Yulong Wang

In this paper, we propose a numerical scheme for structured population models defined on a separable and complete metric space. In particular, we consider a generalized version of a transport equation with additional growth and non-local…

Numerical Analysis · Mathematics 2026-03-19 Carolin Lindow , Christian Düll , Piotr Gwiazda , Błażej Miasojedow , Anna Marciniak-Czochra

In this paper, we consider nonparametric multidimensional finite mixture models and we are interested in the semiparametric estimation of the population weights. Here, the i.i.d. observations are assumed to have at least three components…

Statistics Theory · Mathematics 2017-12-14 Elisabeth Gassiat , Judith Rousseau , Elodie Vernet

In this paper, we study the classical problem of estimating the proportion of a finite population. First, we consider a fixed sample size method and derive an explicit sample size formula which ensures a mixed criterion of absolute and…

Statistics Theory · Mathematics 2009-02-03 Xinjia Chen

We consider a hierarchically structured population in which the amount of resources an individual has access to is affected by individuals that are larger, and that the intake of resources by an individual only affects directly the growth…

Analysis of PDEs · Mathematics 2024-07-15 Carles Barril , Àngel Calsina , József Z. Farkas

A scheme is developed for estimating state-dependent drift and diffusion coefficients in a stochastic differential equation from time-series data. The scheme does not require to specify parametric forms for the drift and diffusion…

Biological Physics · Physics 2012-09-28 Jun Ohkubo

We study a class of nonlinear nonparametric inverse problems. Specifically, we propose a nonparametric estimator of the dynamics of a monotonically increasing trajectory defined on a finite time interval. Under suitable regularity…

Statistics Theory · Mathematics 2014-08-25 Debashis Paul , Jie Peng , Prabir Burman
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