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In active matter systems, self-propelled particles can self-organize to undergo collective motion, leading to persistent dynamical behavior out of equilibrium. In cells, cytoskeletal filaments and motor proteins self-organize into complex…

Soft Condensed Matter · Physics 2020-05-19 Jeffrey M. Moore , Tyler N. Thompson , Matthew A. Glaser , Meredith D. Betterton

Single and collective cellular oscillations involving the actomyosin cytoskeleton have been observed in numerous biological systems. We show here that a generic model of a contractile material, which is turning over and contracts against an…

Biological Physics · Physics 2014-02-24 Kai Dierkes , Angughali Sumi , Jérôme Solon , Guillaume Salbreux

Motile cilia beat in an asymmetric fashion in order to propel the surrounding fluid. When many cilia are located on a surface, their beating can synchronise such that their phases form metachronal waves. Here, we computationally study a…

Soft Condensed Matter · Physics 2023-09-29 David J. Hickey , Ramin Golestanian , Andrej Vilfan

Motile cilia are a striking example of functional cellular organelle, conserved across all the eukaryotic species. Motile cilia allow swimming of cells and small organisms and transport of liquids across epithelial tissues. Whilst the…

Tissues and Organs · Quantitative Biology 2020-01-13 Pietro Cicuta

Large arrays of active cilia coordinate their beat cycles into metachronal waves. These waves can travel in different directions with respect to the cilium's beat direction and the resulting direction of fluid propulsion. Hydrodynamic…

Biological Physics · Physics 2023-09-18 Rachel R. Bennett

Biological systems are robust to perturbations at both the genetic and environmental levels. Yet, these same perturbations can elicit variation in behavior. The interplay between functional robustness and behavioral variability is…

Biological Physics · Physics 2021-06-03 Veikko Geyer , Jonathon Howard , Pablo Sartori

Spherical cellular aggregates are in vitro systems to study the physical and biophysical properties of tissues. We present a novel approach to characterize the mechanical properties of cellular aggregates using micropipette aspiration…

Ciliated tissues such as in the mammalian lungs, brains, and reproductive tracts, are specialized to pump fluid. They generate flows by the collective activity of hundreds of thousands of individual cilia that beat in a striking metachronal…

Soft Condensed Matter · Physics 2022-11-30 Anup Kanale , Feng Ling , Hanliang Guo , Sebastian Fuerthauer , Eva Kanso

We study a slender filament beating in a viscous fluid with novel curvature-dependent bending stiffness. Our numerical and experimental investigations reveal that such differential stiffness can sustain planar bending waves far along…

Motivated by recent simulations and by experiments on aggregation of gliding bacteria, we study a model of the collective dynamics of self-propelled hard rods on a substrate in two dimensions. The rods have finite size, interact via…

Soft Condensed Matter · Physics 2009-11-13 Aparna Baskaran , M. Cristina Marchetti

Collections of simple, self-propelled colloidal particles exhibit complex, emergent dynamical behavior, with promising applications in microrobotics. When confined within a deformable vesicle, self-propelled rods cluster and align,…

Soft Condensed Matter · Physics 2025-10-28 Sophie Y. Lee , Philipp W. A. Schönhöfer , Sharon C. Glotzer

Propelling microorganisms through fluids and moving fluids along cellular surfaces are essential biological functions accomplished by long, thin structures called motile cilia and flagella, whose regular, oscillatory beating breaks the…

Motile cilia are slender, hair-like cellular appendages that spontaneously oscillate under the action of internal molecular motors and are typically found in dense arrays. These active filaments coordinate their beating to generate…

Soft Condensed Matter · Physics 2022-01-28 Brato Chakrabarti , Sebastian Fürthauer , Michael J. Shelley

Self organization mechanisms are essential for the cytoskeleton to adapt to the requirements of living cells. They rely on the intricate interplay of cytoskeletal filaments, crosslinking proteins and molecular motors. Here we present an in…

Biological Physics · Physics 2015-05-28 Simone Köhler , Volker Schaller , Andreas R. Bausch

Asymmetries and anisotropies are widespread in biological systems, including in the structure and dynamics of cilia and eukaryotic flagella. These microscopic, hair-like appendages exhibit asymmetric beating patterns that break…

Soft Condensed Matter · Physics 2025-08-22 Bethany Clarke , Yongyun Hwang , Eric E Keaveny

Networks of biofilaments are essential for the formation of cellular structures that support various biological functions. For the most part, previous studies have investigated the collective dynamics of rod-like biofilaments; however, the…

Biological Physics · Physics 2016-05-18 Hironobu Nogucci , Shuji Ishihara

A variety of swimming microorganisms, called ciliates, exploit the bending of a large number of small and densely-packed organelles, termed cilia, in order to propel themselves in a viscous fluid. We consider a spherical envelope model for…

Fluid Dynamics · Physics 2011-08-30 Sebastien Michelin , Eric Lauga

Bacteria can spontaneously develop collective motions by aligning their motions in dense systems. Here, we show that bacteria can also respond collectively to an alternating electrical field and form dynamic clusters oscillating at the same…

Soft Condensed Matter · Physics 2022-10-11 Mei Mei Bao , Isaiah Eze Igwe , Kang Chen , Tian Hui Zhang

Active colloids are microscopic particles, which self-propel through viscous fluids by converting energy extracted from their environment into directed motion. We first explain how articial microswimmers move forward by generating…

Soft Condensed Matter · Physics 2016-05-12 Andreas Zöttl , Holger Stark

In this review article, we focus on collective motion in externally driven colloidal suspensions, as well as how these collective effects can be harnessed for use in microfluidic applications. We highlight the leading role of hydrodynamic…

Soft Condensed Matter · Physics 2018-11-01 Michelle Driscoll , Blaise Delmotte