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The relationship between epidemiology, mathematical modeling and computational tools allows to build and test theories on the development and battling of a disease. This PhD thesis is motivated by the study of epidemiological models applied…

Optimization and Control · Mathematics 2014-01-30 Helena Sofia Rodrigues

The resurgence of vector-borne diseases is an increasing public health concern, and there is a need for a better understanding of their dynamics. For a number of diseases, e.g. dengue and chikungunya, this resurgence occurs mostly in urban…

Populations and Evolution · Quantitative Biology 2017-04-14 Abderrahman Iggidr , Gauthier Sallet , Max O. Souza

Dengue transmission is shaped by the population dynamics of the Aedes aegypti mosquito, making vector control a central strategy for disease mitigation. The impact of interventions such as larvicide, adulticide, and breeding-site reduction…

Dynamical Systems · Mathematics 2026-05-13 Aram Vajdi , Lee W. Cohnstaedt , Caterina M. Scoglio , Heman Shakeri

According to the World Health Organization the global incidence rate of dengue infections have risen drastically in recent years. It is estimated that globally the number of new infections is in the range of $100$ to $400$ million per…

Populations and Evolution · Quantitative Biology 2021-11-09 Jozsef Z. Farkas , Stephen A. Gourley , Rongsong Liu

In this paper we propose some mathematical models for the transmission of dengue using a system of reaction-diffusion equations. The mosquitoes are divided into infected, uninfected and aquatic subpopulations, while the humans, which are…

Analysis of PDEs · Mathematics 2018-11-21 Felipo Bacani , Stylianos Dimas , Igor Leite Freire , Norberto Anibal Maidana , Mariano Torrisi

After their re-emergence in the last decades, dengue fever and other vector-borne diseases are a potential threat to the lives of millions of people. Based on a data set of dengue cases in the Brazilian city of Fortaleza, collected from…

We investigate how key epidemiological parameters shape both seasonal epidemics and the persistence of dengue transmission. Our findings confirm known mechanistic drivers of epidemic variability and introduce a ranking of parameter…

Populations and Evolution · Quantitative Biology 2026-05-22 Cesar Alberto Rosales-Alcantar , Marcos A. Capistrán

We present a SIR+ASI epidemic model to describe the interaction between human and dengue fever mosquito populations. A control strategy in the form of vaccination, to decrease the number of infected individuals, is used. An optimal control…

Optimization and Control · Mathematics 2011-09-19 Helena Sofia Rodrigues , M. Teresa T. Monteiro , Delfim F. M. Torres

Dengue is a vector borne disease transmitted to humans by {\it{Aedes Aegypti}} mosquitoes carrying Dengue virus of different serotypes. Primarily an urban epidemic, Dengue exhibits complex spatial and temporal dynamics, influenced by many…

Populations and Evolution · Quantitative Biology 2015-04-30 Murali Krishna Enduri , Shivakumar Jolad

The current manuscript introduce a single-strain dengue model developed from stochastic processes incorporating fractional order transmission and recovery. The fractional derivative has been introduced within the context of transmission and…

Dynamical Systems · Mathematics 2024-10-28 Tahajuddin Sk , Kaushik Bal , Santosh Biswas , Tridip Sardar

Controlling diseases such as dengue fever, chikungunya and zika fever by introduction of the intracellular parasitic bacterium Wolbachia in mosquito populations which are their vectors, is presently quite a promising tool to reduce their…

Optimization and Control · Mathematics 2019-03-05 Pierre-Alexandre Bliman

As the development of a dengue vaccine is ongoing, we simulate an hypothetical vaccine as an extra protection to the population. In a first phase, the vaccination process is studied as a new compartment in the model, and different ways of…

Optimization and Control · Mathematics 2013-11-26 Helena Sofia Rodrigues , M. Teresa T. Monteiro , Delfim F. M. Torres

Dengue control in India is a challenging task due to complex healthcare settings. In yesteryears, an amplification of dengue infections in India posed the need for introspection of existing dengue control policies. Prior understanding of…

Populations and Evolution · Quantitative Biology 2021-06-29 Indrajit Ghosh , Pankaj Kumar Tiwari , Joydev Chattopadhyay

A two-patch mathematical model of Dengue virus type 2 (DENV-2) that accounts for vectors' vertical transmission and between patches human dispersal is introduced. Dispersal is modeled via a Lagrangian approach. A host-patch residence-times…

Populations and Evolution · Quantitative Biology 2016-01-26 Derdei Bichara , Susan A. Holechek , Jorge Velazquez-Castro , Anarina L. Murillo , Carlos Castillo-Chavez

Epidemiological models may give some basic guidelines for public health practitioners, allowing to analyze issues that can influence the strategies to prevent and fight a disease. To be used in decision-making, however, a mathematical model…

Populations and Evolution · Quantitative Biology 2013-08-15 Helena Sofia Rodrigues , M. Teresa T. Monteiro , Delfim F. M. Torres

Medical statistics reveal a significant dependence of hospitalized dengue patient on the patient's age. To incorporate an age-dependence into a mathematical model, we extend the classical ODE system of disease dynamics to a PDE system. The…

Populations and Evolution · Quantitative Biology 2019-08-27 N. C. Ganegoda , T. Götz , K. P. Wijaya

Vector-transmitted diseases such as dengue fever and chikungunya have been spreading rapidly in many parts of the world. The Zika virus has been known since 1947 and invaded South America in 2013. It can be transmitted not only by…

Populations and Evolution · Quantitative Biology 2016-08-23 Fred Brauer , Carlos Castillo-Chavez , Anuj Mubayi , Sherry Towers

In mathematical epidemiology, epidemic control often aims at driving the number of infected individuals to zero, asymptotically. However , during the transitory phase, the number of infected can peak at high values. In this paper, we…

Optimization and Control · Mathematics 2015-10-06 Michel De Lara , Lilian Sofia Sepulveda Salcedo

Dengue is a serious health problem in the Philippines. In 2016, the Department of Health of the country launched a dengue vaccination campaign using Dengvaxia. However, the campaign was mired with controversy and the use of Dengvaxia was…

Populations and Evolution · Quantitative Biology 2019-08-07 Michelle N. Raza , Randy L. Caga-anan

Dengue is a vector-borne disease transmitted by Aedes mosquitoes. The worldwide spread of these mosquitoes and the increasing disease burden have emphasized the need for a spatio-temporal risk map capable of assessing dengue outbreak…

Applications · Statistics 2023-10-11 Aram Vajdi , Lee W. Cohnstaedt , Caterina M. Scoglio