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Random allocation is essential for causal inference, but practical constraints often require assigning participants in clusters. They may be stratified pre-assignment, either of necessity or to reduce differences between treatment and…

Methodology · Statistics 2025-05-27 Xinhe Wang , Ben B. Hansen

Social scientists have increasingly turned to audit experiments to investigate discrimination in the market for jobs, loans, housing and other opportunities. In a typical audit experiment, researchers assign ``signals'' (the treatment) to…

Methodology · Statistics 2025-03-14 Nicole Pashley , Brian Libgober , Tirthankar Dasgupta

Response-adaptive designs allow the randomization probabilities to change during the course of a trial based on cumulated response data, so that a greater proportion of patients can be allocated to the better performing treatments. A major…

Methodology · Statistics 2020-06-03 David S. Robertson , James M. S. Wason

This letter presents a novel adaptive power division strategy, which uses two rectifying diodes with nonlinear impedance characteristics that are configured in parallel to function optimally at their individual power levels. Through the…

Applied Physics · Physics 2026-01-09 Zhongqi He , Liping Yan , Changjun Liu

There has been a split in the statistics community about the need for taking covariates into account in the design phase of a clinical trial. There are many advocates of using stratification and covariate-adaptive randomization to promote…

Methodology · Statistics 2011-02-21 William F. Rosenberger , Oleksandr Sverdlov

We consider how increasingly available observational data can be used to improve the design of randomized controlled trials (RCTs). We seek to design a prospective RCT, with the intent of using an Empirical Bayes estimator to shrink the…

Methodology · Statistics 2022-04-15 Evan T. R. Rosenman , Luke Miratrix

Completely randomized experiments have been the gold standard for drawing causal inference because they can balance all potential confounding on average. However, they may suffer from unbalanced covariates for realized treatment…

Statistics Theory · Mathematics 2022-10-18 Yuhao Wang , Xinran Li

We propose a novel adaptive design for clinical trials with time-to-event outcomes and covariates (which may consist of or include biomarkers). Our method is based on the expected entropy of the posterior distribution of a proportional…

Applications · Statistics 2016-03-29 James E. Barrett

Optimal block designs for additive models achieve their efficiency by dividing experimental units among relatively homogenous blocks and allocating treatments equally to blocks. Responses in many modern experiments, however, are drawn from…

Methodology · Statistics 2016-01-05 Stephen Bush , Katya Ruggiero

Randomized saturation designs are a family of designs which assign a possibly different treatment proportion to each cluster of a population at random. As a result, they generalize the well-known (stratified) completely randomized designs…

Methodology · Statistics 2022-03-21 Chencheng Cai , Jean Pouget-Abadie , Edoardo M. Airoldi

A recent method using Dynamic Linear Models to improve preferred treatment allocation budget in random allocation models was proposed by Lee, Boone, et al (2020). However this model failed to include the impact covariates such as smoking,…

Applications · Statistics 2020-09-24 Albert H. Lee

In randomized experiments, the actual treatments received by some experimental units may differ from their treatment assignments. This non-compliance issue often occurs in clinical trials, social experiments, and the applications of…

Methodology · Statistics 2022-04-19 Jiyang Ren

Response-adaptive allocation designs refer to a class of designs where the probability an observation is assigned to a treatment is changed throughout an experiment based on the accrued responses. Such procedures result in random treatment…

Methodology · Statistics 2022-08-04 Adam Lane

We study clustered multitask learning in a semiparametric setting where tasks share a latent cluster structure in their target parameters but exhibit heterogeneous, potentially infinite-dimensional nuisance components. Such heterogeneity…

Machine Learning · Statistics 2026-05-05 Hanxiao Chen , Debarghya Mukherjee

Optimal treatment rules can improve health outcomes on average by assigning a treatment associated with the most desirable outcome to each individual. Due to an unknown data generation mechanism, it is appealing to use flexible models to…

Methodology · Statistics 2023-11-21 Lingjie Shen , Gijs Geleijnse , Maurits Kaptein

We study the design of adaptive, sequential experiments for unbiased average treatment effect (ATE) estimation in the design-based potential outcomes setting. Our goal is to develop adaptive designs offering sublinear Neyman regret, meaning…

Methodology · Statistics 2025-02-25 Georgy Noarov , Riccardo Fogliato , Martin Bertran , Aaron Roth

While experimental design often focuses on selecting the single best alternative from a finite set (e.g., in ranking and selection or best-arm identification), many pure-exploration problems pursue richer goals. Given a specific goal,…

Machine Learning · Statistics 2025-05-28 Chao Qin , Wei You

Randomized experiments (often known as "A/B tests") are widely used to evaluate product and service innovations. We study how to allocate limited experimentation resources across M concurrent experiments in an experiment-rich regime.…

Methodology · Statistics 2026-03-19 Fenghua Yang , Dae Woong Ham , Stefanus Jasin

In the problem of domain adaptation for binary classification, the learner is presented with labeled examples from a source domain, and must correctly classify unlabeled examples from a target domain, which may differ from the source.…

Machine Learning · Statistics 2019-03-01 Clayton Scott

This paper proposes a novel criterion for the allocation of patients in Phase~I dose-escalation clinical trials aiming to find the maximum tolerated dose (MTD). Conventionally, using a model-based approach the next patient is allocated to…

Methodology · Statistics 2018-07-17 Pavel Mozgunov , Thomas Jaki