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A methodology is proposed to automatically detect significant symbol associations in genomic databases. A new statistical test is proposed to assess the significance of a group of symbols when found in several genesets of a given database.…

Genomics · Quantitative Biology 2013-09-11 Bernard Ycart , Frédéric Pont , Jean-Jacques Fournié

Dynamical behaviour of discrete dynamical systems has been investigated extensively in the past few decades. However, in several applications, long term memory plays an important role in the evolution of dynamical variables. The definition…

Dynamical Systems · Mathematics 2022-08-30 Sumit S. Pakhare , Varsha Daftardar-Gejji , Dilip S. Badwaik , Amey Deshpande , Prashant M. Gade

Criteria for piecewise linear circle homeomorphisms to be conjugate to a rigid rotation, $x\to x+\omega~({\rm mod}~1)$, with rational rotation number $\omega$ are given. The consequences of the existence of such maps in families of maps is…

Dynamical Systems · Mathematics 2025-05-21 Paul Glendinning , Siyuan Ma , James Montaldi

We prove a sufficient condition for synchronization for coupled one-dimensional maps and estimate the size of the window of parameters where synchronization takes place. It is shown that coupled systems on graphs with positive eigenvalues…

Chaotic Dynamics · Physics 2015-02-26 Georgi S. Medvedev , Xuezhi Tang

Graphs are ubiquitous data structures for representing interactions between entities. With an emphasis on the use of graphs to represent chemical molecules, we explore the task of learning to generate graphs that conform to a distribution…

Machine Learning · Computer Science 2019-03-08 Qi Liu , Miltiadis Allamanis , Marc Brockschmidt , Alexander L. Gaunt

Due to the deterministic nature of chaotic systems, fluctuations in their trajectories arise solely from the choice of initial conditions. Some of these dynamical fluctuations may lead to extremely unlikely scenarios. Understanding the…

Statistical Mechanics · Physics 2025-07-23 Yllari K. González-Koda , Ricardo Gutiérrez , Carlos Pérez-Espigares

We present a data structure called a history graph that offers a practical basis for the analysis of genome evolution. It conceptually simplifies the study of parsimonious evolutionary histories by representing both substitutions and double…

Genomics · Quantitative Biology 2014-05-13 Benedict Paten , Daniel R. Zerbino , Glenn Hickey , David Haussler

We obtain exact analytical results for lattices of maps with couplings that decay with distance as $r^{-\alpha}$. We analyze the effect of the coupling range on the system dynamics through the Lyapunov spectrum. For lattices whose elements…

Chaotic Dynamics · Physics 2009-11-10 C. Anteneodo , S. E. de S. Pinto , A. M. Batista , R. L. Viana

Mean value and cross-covariance function of chaotic binary sequences are evaluated for chaotic maps with specific properties. We also take into account the effect of fixed- and floating-point representations on statistical properties of…

Chaotic Dynamics · Physics 2008-05-29 Bogdan Cristea

We investigate spatio-temporal dynamics of a 2D ensemble of nonlocally coupled chaotic cubic maps in a bistability regime. In particular, we perform a detailed study on the transition "coherence -- incoherence" for varying coupling strength…

Motivated by empirical observations of algebraic duplicated sequence length distributions in a broad range of natural genomes, we analytically formulate and solve a class of simple discrete duplication/substitution models that generate…

Mathematical Physics · Physics 2013-10-30 M. V. Koroteev , J. Miller

Multipulse sequences based on Carr-Purcell decoupling are frequently used for narrow-band signal detection in single spin magnetometry. We have analyzed the behavior of multipulse sensing sequences under real-world conditions, including…

Quantum Physics · Physics 2015-05-07 M. Loretz , J. M. Boss , T. Rosskopf , H. J. Mamin , D. Rugar , C. L. Degen

Labeled infinite trees provide combinatorial interpretations for many integer sequences generated by nested recurrence relations. Typically, such sequences are monotone increasing. Several of these sequences also have straightforward…

Combinatorics · Mathematics 2022-11-07 Nathan Fox

High-dimensional sample correlation matrices are a crucial class of random matrices in multivariate statistical analysis. The central limit theorem (CLT) provides a theoretical foundation for statistical inference. In this paper, assuming…

Statistics Theory · Mathematics 2024-08-30 Weijiang Chen , Shurong Zheng , Tingting Zou

This paper presents a probabilistic approach for DNA sequence analysis. A DNA sequence consists of an arrangement of the four nucleotides A, C, T and G and different representation schemes are presented according to a probability measure…

Quantitative Methods · Quantitative Biology 2010-02-12 Amrita Priyam , B. M. Karan , G. Sahoo

Recent studies in ecology and epidemiology indicate that it is important to include spatial heterogeneity, synchronization and seasonality in the theoretical models. In this work, spatial heterogeneity is introduced via coupled map lattices…

Statistical Mechanics · Physics 2007-05-23 E. Ahmed , A. S. Hegazi , A. S. Elgazzar , H. M. Yehia

Graph neural networks (GNNs) demonstrate great performance in compound property and activity prediction due to their capability to efficiently learn complex molecular graph structures. However, two main limitations persist including…

Biomolecules · Quantitative Biology 2023-10-10 Apakorn Kengkanna , Masahito Ohue

To understand the nature of a cell, one needs to understand the structure of its genome. For this purpose, experimental techniques such as Hi-C detecting chromosomal contacts are used to probe the three-dimensional genomic structure. These…

Quantitative Methods · Quantitative Biology 2019-09-23 Andreas Hofmann , Fatema Zahra Rashid , Frédéric Crémazy , Remus T. Dame , Dieter W. Heermann

We study iteration maps of recurrence relations arising from mutation periodic quivers of arbitrary period. Combining tools from cluster algebra theory and (pre)symplectic geometry, we show that these cluster iteration maps can be reduced…

Symplectic Geometry · Mathematics 2013-07-02 Inês Cruz , M. Esmeralda Sousa-Dias

Dynamical systems with a coupled cell network structure can display synchronous solutions, spectral degeneracies and anomalous bifurcation behavior. We explain these phenomena here for homogeneous networks, by showing that every homogeneous…

Dynamical Systems · Mathematics 2013-04-05 Bob Rink , Jan Sanders