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We investigate conductance and conductance fluctuations of two transmembrane proteins, bacteriorhodopsin and proteorhodopsin, belonging to the family of protein light receptors. These proteins are widely diffused in aqueous environments,…

Soft Condensed Matter · Physics 2013-05-27 E. Alfinito , J. Pousset , L. Reggiani

When moving from native to light activated bacteriorhodopsin, modification of charge transport consisting of an increase of conductance is correlated to the protein conformational change. A theoretical model based on a map of the protein…

Quantitative Methods · Quantitative Biology 2011-02-17 Eleonora Alfinito , Lino Reggiani

Using numerical modeling we study emergence of structure and structure-related nonlinear conduction properties in the self-assembled nanoparticle films. Particularly, we show how different nanoparticle networks emerge within assembly…

Soft Condensed Matter · Physics 2010-10-07 Milovan Suvakov , Bosiljka Tadic

Current voltage (I-V) characteristics in proteins can be sensitive to conformational change induced by an external stimulus (photon, odour, etc.). This sensitivity can be used in medical and industrial applications besides shedding new…

Soft Condensed Matter · Physics 2015-05-28 Eleonora Alfinito , Jean-Francois Millithaler , Lino Reggiani

We investigate a particular phase transition between two different tunneling regimes, direct and injection (Fowler-Nordheim), experimentally observed in the current-voltage characteristics of the light receptor bacteriorhodopsin (bR). Here,…

Statistical Mechanics · Physics 2012-04-17 E. Alfinito , J. F. Millithaler , L. Reggiani

The effect of fluctuations on the conductivity of ion channels is investigated. It is shown that modulation of the potential barrier at the selectivity site due to electrostatic amplification of charge fluctuations at the channel mouth…

Biological Physics · Physics 2009-11-13 D. G. Luchinsky , R. Tindjong , I. Kaufman , P. V. E. McClintock , R. S. Eisenberg

We report a theoretical/computational approach for modeling the current-voltage characteristics of sensing proteins. The modeling is applied to a couple of transmembrane proteins, bacteriorhodopsin and proteorhodopsin, sensitive to visible…

Biological Physics · Physics 2014-02-04 E Alfinito , J Pousset , L Reggiani

Bacteria meticulously regulate their intracellular ion concentrations and create ionic concentration gradients across the bacterial membrane. These ionic concentration gradients provide free energy for many cellular processes and are…

Applied Physics · Physics 2022-07-05 Yichao Yang , Hagen Gress , Kamil L. Ekinci

The fluctuations of the charge on an electrode contain information on the microscopic correlations within the adjacent fluid and their effect on the electronic properties of the interface. We investigate these fluctuations using molecular…

The energetic properties of electron transport in mesoscopic and nanoscale conductors is of large current interest. Here we theoretically investigate the possibility of probing fluctuations of charge and heat currents as well as their mixed…

Mesoscale and Nanoscale Physics · Physics 2018-08-15 Nastaran Dashti , Maciej Misiorny , Peter Samuelsson , Janine Splettstoesser

The transport of molecules through biological and synthetic nanopores is governed by multiple stochastic processes that lead to noisy, fluctuating currents. Disentangling the characteristics of different noise-generating mechanisms is…

Soft Condensed Matter · Physics 2024-10-03 Stuart F. Knowles , Eleanor K. R. Mackay , Alice L. Thorneywork

We have investigated the transport and noise properties of submicron YBCO bicrystal grain-boundary junctions prepared using electron beam lithography. The junctions show an increased conductance for low voltages reminiscent of Josephson…

Superconductivity · Physics 2009-10-31 F. Herbstritt , T. Kemen , L. Alff , A. Marx , R. Gross

Various charge migration mechanisms in the DNA are studied within the framework of the Peyrard-Bishop-Holstein model which has been widely used to address charge dynamics in this macromolecule. To analyze these mechanisms we consider…

Biological Physics · Physics 2022-09-14 R. P. A. Lima , A. V. Malyshev

We analyze the transport properties of a semiconductor based bilayer system under non-equilibrium conditions with special emphasis on the charge transfer statistics in the regime dominated by the exciton transport. We consider two different…

Mesoscale and Nanoscale Physics · Physics 2013-08-06 H. Soller , A. Komnik

We study fluctuations of particle absorption by a three-dimensional domain with multiple absorbing patches. The domain is in contact with a gas of interacting diffusing particles. This problem is motivated by living cell sensing via…

Statistical Mechanics · Physics 2017-06-28 Tal Agranov , Baruch Meerson

The frequency-dependent spectrum of current fluctuations through nano-scale channels is studied using analytical and computational techniques. Using a stochastic Nernst-Planck description and neglecting the interactions between the ions…

Statistical Mechanics · Physics 2018-04-04 Mira Zorkot , Ramin Golestanian

We present a stochastic approach for charge transport in transistors. In this approach, the electron and hole densities are governed by diffusion-reaction stochastic differential equations satisfying local detailed balance and the electric…

Statistical Mechanics · Physics 2021-02-08 Jiayin Gu , Pierre Gaspard

We analyze charge tunneling statistics and current noise in a superconducting single-electron transistor in a regime where the Josephson-quasiparticle cycle is the dominant mechanism of transport. Due to the interplay between Coulomb…

Mesoscale and Nanoscale Physics · Physics 2009-11-07 Mahn-Soo Choi , Francesco Plastina , Rosario Fazio

Ion transport in biological and synthetic nanochannels is characterized by such phenomena as ion current fluctuations, rectification, and pumping. Recently, it has been shown that the nanofabricated synthetic pores could be considered as…

Chemical Physics · Physics 2009-11-11 I. D. Kosinska

Recently, a growing interest has been addressed to the electrical properties of bacteriorhodopsin (bR), a protein belonging to the transmembrane protein family. To take into account the structure-dependent nature of the current, in a…

Soft Condensed Matter · Physics 2015-03-06 E. Alfinito , L. Reggiani
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