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The $c$-approximate Near Neighbor problem in high dimensional spaces has been mainly addressed by Locality Sensitive Hashing (LSH), which offers polynomial dependence on the dimension, query time sublinear in the size of the dataset, and…

Computational Geometry · Computer Science 2016-12-23 Georgia Avarikioti , Ioannis Z. Emiris , Ioannis Psarros , Georgios Samaras

To obtain an electron-density map from a macromolecular crystal the phase-problem needs to be solved, which often involves the use of heavy-atom derivative crystals and concomitantly the determination of the heavy atom substructure. This is…

Biomolecules · Quantitative Biology 2018-08-20 Bjørn Panyella Pedersen , Pontus Gourdon , Xiangyu Liu , Jesper Lykkegaard Karlsen , Poul Nissen

We address protein structure prediction in the 3D Hydrophobic-Polar lattice model through two novel deep learning architectures. For proteins under 36 residues, our hybrid reservoir-based model combines fixed random projections with…

Machine Learning · Computer Science 2024-12-31 Giovanny Espitia , Yui Tik Pang , James C. Gumbart

We present an efficient algorithm to recover the three dimensional structure of a protein from its contact map representation. First we show that when a physically realizable map is used as target, our method generates a structure whose…

Soft Condensed Matter · Physics 2008-02-03 Michele Vendruscolo , Edo Kussell , Eytan Domany

Point cloud data, as the representation of three-dimensional spatial information, is a fundamental piece of information in various domains where indexing and querying these point clouds efficiently is crucial for tasks such as object…

Data Structures and Algorithms · Computer Science 2025-02-19 Ruben Laso , Miguel Yermo

Among many solutions to the high-dimensional approximate nearest neighbor (ANN) search problem, locality sensitive hashing (LSH) is known for its sub-linear query time and robust theoretical guarantee on query accuracy. Traditional LSH…

Databases · Computer Science 2022-07-21 Yao Tian , Xi Zhao , Xiaofang Zhou

Motivation Protein fold recognition is an important problem in structural bioinformatics. Almost all traditional fold recognition methods use sequence (homology) comparison to indirectly predict the fold of a tar get protein based on the…

Machine Learning · Computer Science 2017-06-06 Jie Hou , Badri Adhikari , Jianlin Cheng

Quantum search algorithms are considered in the context of protein sequence comparison in biocomputing. Given a sample protein sequence of length m (i.e m residues), the problem considered is to find an optimal match in a large database…

Quantum Physics · Physics 2009-11-06 Lloyd C. L. Hollenberg

Table structure recognition is a challenging task due to the various structures and complicated cell spanning relations. Previous methods handled the problem starting from elements in different granularities (rows/columns, text regions),…

Computer Vision and Pattern Recognition · Computer Science 2022-04-21 Liang Qiao , Zaisheng Li , Zhanzhan Cheng , Peng Zhang , Shiliang Pu , Yi Niu , Wenqi Ren , Wenming Tan , Fei Wu

This chapter gives a graceful introduction to problem of protein three- dimensional structure prediction, and focuses on how to make structural sense out of a single input sequence with unknown structure, the 'query' or 'target' sequence.…

Biomolecules · Quantitative Biology 2017-12-04 Sanne Abeln , Jaap Heringa , K. Anton Feenstra

Due to the compelling efficiency in retrieval and storage, similarity-preserving hashing has been widely applied to approximate nearest neighbor search in large-scale image retrieval. However, existing methods have poor performance in…

Multimedia · Computer Science 2020-04-27 Xingbo Liu , Xiushan Nie , Qi Dai , Yupan Huang , Yilong Yin

Analysis of the sequence-structure relationship in RNA molecules are essential to evolutionary studies but also to concrete applications such as error-correction methodologies in sequencing technologies. The prohibitive sizes of the…

Quantitative Methods · Quantitative Biology 2013-05-31 Vladimir Reinharz , Yann Ponty , Jérôme Waldispühl

Locality-sensitive hashing (LSH) has emerged as the dominant algorithmic technique for similarity search with strong performance guarantees in high-dimensional spaces. A drawback of traditional LSH schemes is that they may have \emph{false…

Databases · Computer Science 2016-08-22 Ninh Pham , Rasmus Pagh

IP lookup via Longest Prefix Match (LPM) is critical for packet forwarding. Unfortunately, conventional lookup algorithms are inefficient for IPv6 Forwarding Information Bases (FIBs), which are characterized by a set of long prefixes with…

Data Structures and Algorithms · Computer Science 2026-04-29 Zhihao Zhang , Lanzheng Liu , Chen Chen , Huiba Li , Jiwu Shu , Windsor Hsu , Yiming Zhang

The use of automatic methods, often referred to as Neural Architecture Search (NAS), in designing neural network architectures has recently drawn considerable attention. In this work, we present an efficient NAS approach, named HM- NAS,…

Machine Learning · Computer Science 2019-09-10 Shen Yan , Biyi Fang , Faen Zhang , Yu Zheng , Xiao Zeng , Hui Xu , Mi Zhang

In this paper, we address the problem of searching for semantically similar images from a large database. We present a compact coding approach, supervised quantization. Our approach simultaneously learns feature selection that linearly…

Computer Vision and Pattern Recognition · Computer Science 2019-02-05 Xiaojuan Wang , Ting Zhang , Guo-Jun Q , Jinhui Tang , Jingdong Wang

The abilities of modern large language models (LLMs) in solving natural language processing, complex reasoning, sentiment analysis and other tasks have been extraordinary which has prompted their extensive adoption. Unfortunately, these…

Artificial Intelligence · Computer Science 2024-05-29 Anthony Sarah , Sharath Nittur Sridhar , Maciej Szankin , Sairam Sundaresan

By using a mixture model for the density distribution of the three pseudobond angles formed by $C_\alpha$ atoms of four consecutive residues, the local structural states are discretized as 17 conformational letters of a protein structural…

Biomolecules · Quantitative Biology 2007-05-23 Wei-Mou Zheng , Xin Liu

Nearest neighbor search aims to obtain the samples in the database with the smallest distances from them to the queries, which is a basic task in a range of fields, including computer vision and data mining. Hashing is one of the most…

Computer Vision and Pattern Recognition · Computer Science 2022-04-26 Xiao Luo , Haixin Wang , Daqing Wu , Chong Chen , Minghua Deng , Jianqiang Huang , Xian-Sheng Hua

Due to the growth of geo-tagged images, recent web and mobile applications provide search capabilities for images that are similar to a given query image and simultaneously within a given geographical area. In this paper, we focus on…

Databases · Computer Science 2017-02-20 Abdullah Alfarrarjeh , Cyrus Shahabi