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Self-consistency (SC) is a widely used test-time inference technique for improving performance in chain-of-thought reasoning. It involves generating multiple responses, or samples from a large language model (LLM) and selecting the most…

Machine Learning · Computer Science 2025-11-18 Austin Feng , Marius Alonso , Ambroise Odonnat

This paper proposes a method for visually explaining the decision-making process of video recognition networks with a temporal extension of occlusion sensitivity analysis, called Adaptive Occlusion Sensitivity Analysis (AOSA). The key idea…

Computer Vision and Pattern Recognition · Computer Science 2023-08-21 Tomoki Uchiyama , Naoya Sogi , Satoshi Iizuka , Koichiro Niinuma , Kazuhiro Fukui

Multi-modality pre-training paradigm that aligns protein sequences and biological descriptions has learned general protein representations and achieved promising performance in various downstream applications. However, these works were…

Machine Learning · Computer Science 2024-12-31 Hanjing Zhou , Mingze Yin , Wei Wu , Mingyang Li , Kun Fu , Jintai Chen , Jian Wu , Zheng Wang

Consider the convex hull of a collection of disjoint open discs with radii $1/2$. The boundary of the convex hull consists of a finite number of line segments and arcs. Randomly choose a point in one of the arcs in the boundary so that the…

Probability · Mathematics 2025-08-13 Krzysztof Burdzy

Soft Actor Critic (SAC) algorithms show remarkable performance in complex simulated environments. A key element of SAC networks is entropy regularization, which prevents the SAC actor from optimizing against fine grained features,…

Machine Learning · Computer Science 2020-06-23 Miguel Campo , Zhengxing Chen , Luke Kung , Kittipat Virochsiri , Jianyu Wang

Visual anomaly detection is essential in industrial manufacturing, yet traditional methods often rely heavily on extensive normal datasets and task-specific models, limiting their scalability. Recent advancements in large-scale…

Computer Vision and Pattern Recognition · Computer Science 2024-11-20 Zongxiang Hu , Zhaosheng Zhang

Membrane curvature sensing is essential for a diverse range of biological processes. Recent experiments have revealed that a single nanometer-sized septin protein can distinguish between membrane-coated glass beads of one micron and three…

Biological Physics · Physics 2024-07-22 Indrajit Badvaram , Brian A. Camley

Modern wide field radio surveys typically detect millions of objects. Techniques based on machine learning are proving to be useful for classifying large numbers of objects. The self-organizing map (SOM) is an unsupervised machine learning…

A novel scheme is introduced to capture the spatial correlations of consecutive amino acids in naturally occurring proteins. This knowledge-based strategy is able to carry out optimally automated subdivisions of protein fragments into…

Soft Condensed Matter · Physics 2007-05-23 Cristian Micheletti , Flavio Seno , Amos Maritan

The computational analysis of Mass Spectrometry Imaging (MSI) data aims at the identification of interesting mass co-localizations and the visualization of their lateral distribution in the sample, usually a tissue cross section. But as the…

Computer Vision and Pattern Recognition · Computer Science 2020-10-01 Karsten Wüllems , Tim W. Nattkemper

With the application of high-frequency communication and extremely large MIMO (XL-MIMO), the near-field effect has become increasingly apparent. The near-field beam design now requires consideration not only of the angle of arrival (AoA)…

Information Theory · Computer Science 2023-12-18 Xiyuan Liu , Qingqing Wu , Rui Wang , Jun Wu

Representational similarity analysis (RSA) is a multivariate technique to investigate cortical representations of objects or constructs. While avoiding ill-posed matrix inversions that plague multivariate approaches in the presence of many…

Methodology · Statistics 2021-12-03 Roberto Viviani

Protein interaction networks are a promising type of data for studying complex biological systems. However, despite the rich information embedded in these networks, they face important data quality challenges of noise and incompleteness…

Molecular Networks · Quantitative Biology 2012-10-29 Gaurav Pandey , Sahil Manocha , Gowtham Atluri , Vipin Kumar

The precise sequence of aminoacids plays a central role in the tertiary structure of proteins and their functional properties. The Hydrophobic-Polar lattice models have provided valuable insights regarding the energy landscape. We…

Biomolecules · Quantitative Biology 2015-03-30 K. Silpaja Chandrasekar , M. V. Sangaranarayanan

Context: Championed by IBM's vision of autonomic computing paper in 2003, the autonomic computing research field has seen increased research activity over the last 20 years. Several conferences and workshops have been established and have…

Software Engineering · Computer Science 2022-05-03 Terence Wong , Markus Wagner , Christoph Treude

A complex network approach to protein folding is proposed. The graph object is the network of shortcut edges present in a native-state protein (SCN0). Although SCN0s are found via an intuitive message passing algorithm (S. Milgram,…

Molecular Networks · Quantitative Biology 2017-12-15 Susan Khor

Accurate prediction of protein-ligand binding affinity is crucial for rapid and efficient drug development. Recently, the importance of predicting binding affinity has led to increased attention on research that models the three-dimensional…

Machine Learning · Computer Science 2024-07-17 Seungyeon Choi , Sangmin Seo , Sanghyun Park

The question of whether proteins originate from random sequences of amino acids is addressed. A statistical analysis is performed in terms of blocked and random walk values formed by binary hydrophobic assignments of the amino acids along…

chem-ph · Physics 2009-10-28 Anders Irbäck , Carsten Peterson , Frank Potthast

We introduce a novel multiobjective optimization algorithm based on the conformational space annealing (CSA) algorithm, MOCSA. It has three characteristic features: (a) Dominance relationship and distance between solutions in the objective…

Computational Physics · Physics 2012-09-05 Sangjin Sim , Juyong Lee , Jooyoung Lee

Protein structural classification (PSC) is a supervised problem of assigning proteins into pre-defined structural (e.g., CATH or SCOPe) classes based on the proteins' sequence or 3D structural features. We recently proposed PSC approaches…

Molecular Networks · Quantitative Biology 2021-05-18 Khalique Newaz , Jacob Piland , Patricia L. Clark , Scott J. Emrich , Jun Li , Tijana Milenkovic