Related papers: Self-Organized Criticality: A Magic Wand for Prote…
Recent advancements in the synthesis of anisotropic macromolecules and nanoparticles have spurred an immense interest in theoretical and computational studies of self-assembly. The cornerstone of such studies is the role of shape in…
Protein folding -- the problem of predicting the spatial structure of a protein given its sequence of amino-acids -- has attracted considerable research effort in biochemistry in recent decades. In this work, we explore the potential of…
The three dimensional structure of a protein is an outcome of the interactions of its constituent amino acids in 3D space. Considering the amino acids as nodes and the interactions among them as edges we have constructed and analyzed…
Self-Organized Criticality is the emergence of long-ranged spatio-temporal correlations in non-equilibrium steady states of slowly driven systems without fine tuning of any control parameter. Sandpiles were proposed as prototypical examples…
This paper studies referring video object segmentation (RVOS) by boosting video-level visual-linguistic alignment. Recent approaches model the RVOS task as a sequence prediction problem and perform multi-modal interaction as well as…
Signatures of self-organized criticality (SOC) have recently been observed in an ultracold atomic gas under continuous laser excitation to strongly-interacting Rydberg states [S. Helmrich et al., Nature, 577, 481--486 (2020)]. This creates…
This paper presents Orthogonal Subspace Clustering (OSC), an innovative method for high-dimensional data clustering. We first establish a theoretical theorem proving that high-dimensional data can be decomposed into orthogonal subspaces in…
We review the development of thermodynamic protein hydropathic scaling theory, starting from backgrounds in mathematics and statistical mechanics, and leading to biomedical applications. Darwinian evolution has organized each protein family…
Automatic registration of multimodal remote sensing data (e.g., optical, LiDAR, SAR) is a challenging task due to the significant non-linear radiometric differences between these data. To address this problem, this paper proposes a novel…
Motivation: Protein sequence world is discrete as 20 amino acids (AA) while its structure world is continuous, though can be discretized into structural alphabets (SA). In order to reveal the relationship between sequence and structure, it…
A multitude of measures have been proposed to quantify the similarity between protein 3-D structure. Among these measures, contact map overlap (CMO) maximization deserved sustained attention during past decade because it offers a fine…
Each and every biological function in living organism happens as a result of protein-protein interactions.The diseases are no exception to this. Identifying one or more proteins for a particular disease and then designing a suitable…
The 2024 Nobel Prize in Chemistry was awarded in part for protein structure prediction using AlphaFold2, an artificial intelligence/machine learning (AI/ML) model trained on vast amounts of sequence and 3D structure data. AlphaFold2 and…
The principle of self-organization has acquired a fundamental significance in the newly emerging field of computational philosophy. Self-organizing systems have been described in various domains in science and philosophy including physics,…
Online social dynamics based on human endeavours exhibit prominent complexity in the emergence of new features embodied in the appearance of collective social values. The vast amount of empirical data collected at various websites provides…
Lawrence (2001)found computer science articles that were openly accessible (OA) on the Web were cited more. We replicated this in physics. We tested 1,307,038 articles published across 12 years (1992-2003) in 10 disciplines (Biology,…
This paper investigates the application of the transformer architecture in protein folding, as exemplified by DeepMind's AlphaFold project, and its implications for the understanding of so-called large language models. The prevailing…
Circular permutation connects the N and C termini of a protein and concurrently cleaves elsewhere in the chain, providing an important mechanism for generating novel protein fold and functions. However, their in genomes is unknown because…
Semantic correspondence remains a challenging task for establishing correspondences between a pair of images with the same category or similar scenes due to the large intra-class appearance. In this paper, we introduce a novel problem…
Many of the concepts which are at the basis of the development associated with a quantitative treatment of the variety of phenomena associated with the spontaneous breaking of gauge symmetry in nuclei have been instrumental in connection…